Clinical trials: Neurologic Signs
Aphasia
Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia
This study tests whether weak electrical stimulation of the brain is effective in improving language or reading difficulties occurring after a brain injury or stroke.
- Trial name
- NCT01709383
- Testing
- Transcranial Direct Current Stimulation
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Georgetown University
Ischemic Stroke
Improved Prediction of Recurrent Stroke and Detection of Small Volume Stroke
Rationale: Over 20.000 people suffer an ischemic stroke in the Netherlands each year. Large artery occlusions are easy to identify and can be treated with endovascular clot removal.
- Trial name
- ENCLOSE (NCT04019483)
- Where
- 3 sites in Netherlands
- Volunteers
- 439 people
- Sponsor
- UMC Utrecht
Post Operative Pain
Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)
Both morphine and hydromorphone are pain medications commonly used after surgery. It is thought at the institution that hydromorphone causes less side effects but this has not been studied.
- Trial name
- NCT00385541
- Testing
- Morphine PCA, Hydromorphone PCA
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Spinal Cord Injuries (SCI), Neurogenic Lower Urinary Tract Dysfunction
Radio-frequency (RF) Bladder Monitor
The goal of this pilot feasibility study is to evaluate a wearable microwave (MW)-based bladder monitoring system in adult volunteers and those with spinal cord injury (SCI) who use self-catheterization for bladder management.
- Conditions
- Spinal Cord Injuries (SCI), Neurogenic Lower Urinary Tract Dysfunction, Neurogenic Bladder (NB)
- Trial name
- NCT07639541
- Testing
- Wearable microwave Bladder Monitoring System
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
CVA, Gait, Hemiplegic
Robotic Exoskeleton Assisted Gait Post Stroke
The current investigation takes advantage of both a progressive and adaptive assist-as-needed massed practice and time-sensitive neuroplasticity through exoskeleton assisted walking in order to induce greater recovery-oriented…
- Trial name
- RE-Assist (NCT04309305)
- Testing
- EksoGT™, Ekso Bionics, Berkley, CA, USA, Standard of Care, No Intervention
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Dental Pain, Muscle Sensitivity to Pressure
Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children
To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip
- Conditions
- Dental Pain, Muscle Sensitivity to Pressure, Skin Sensitivity to Electric Stimulation
- Trial name
- NCT01022294
- Testing
- Nitrousoxide-oxygen and atmospheric air, Atmospheric air; nitrousoxide-oxygen
- Where
- Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Degenerative Cervical Spine
A Focused Registry on Anterior Cervical Interbody Spacer ACIS
Degenerative cervical spine conditions lead to chronic neck and arm pain. Surgical treatment may require anterior decompression and fusion, which usually is established with a cage implant.
- Trial name
- ACIS (NCT02016794)
- Where
- 2 sites in Belgium
- Volunteers
- 9 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Parkinson Disease(PD)
Adaptive DBS for PD
The goal of this clinical trial is to evaluate the efficacy and safety of an adaptive deep brain stimulation (aDBS) system for managing Parkinson's disease symptoms.
- Trial name
- SMART-DBS (NCT07635823)
- Testing
- adaptive deep brain stimulation, conventional deep brain stimulation
- Where
- 9 sites in China
- Volunteers
- 60 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Essential Tremor, Dystonia
The Development of a System for Measurement of Tremor
The goal of this clinical trial is to develop a system which can be used to measure movements in people with Essential Tremor (with or without dystonia).
- Trial name
- NCT05956223
- Testing
- Virtual Reality measurement of essential tremor and dystonia
- Where
- Australia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- The Bionics Institute of Australia
Chronic Pain
Health-economic Evaluation of Interventional Pain Management Compared to Pain Rehabilitation
The overall aim of the study is to evaluate interventional pain management. This is done in three steps: 1. To find matched controls to the patients in the study on cost-effectiveness of IPM and compare the results. 2.
- Trial name
- NCT04657159
- Testing
- Pain rehabilitation program
- Where
- 2 sites in Sweden
- Volunteers
- 15,611 people
- Sponsor
- Eques Indolor AB
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Voice Disorders, Gastroesophageal Reflux
Quantifying Effects of Treatment of Pediatric Dysphonia
The diagnosis and management of childhood dysphonia is a significant clinical problem; however, there have been few studies aimed at defining standard assessment methods for pediatric dysphonia.
- Trial name
- NCT00237679
- Testing
- Neuromuscular Electrical Stimulation, Unstimulated
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Attention-Deficit/Hyperactivity Disorder (Combined-subtype)
Effect of Working Memory Training on ADHD Brain Function
There is evidence both that computer-administered cognitive training can improve ADHD working memory deficits and that this type of training in non-ADHD enhances normal working memory ability by altering brain activity in…
- Trial name
- NCT02151396
- Testing
- Working memory training, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Hartford Hospital
Stroke, Ischemic Attack, Transient
Carotid Occlusion Surgery Study
The purpose of this study is to determine if extracranial-intracranial bypass surgery when added to best medical therapy can reduce the subsequent risk of ipsilateral stroke in high-risk patients with recently symptomatic carotid…
- Conditions
- Stroke, Ischemic Attack, Transient, Cerebral Infarction
- Trial name
- COSS (NCT00029146)
- Testing
- extracranial-intracranial bypass surgery, best medical therapy
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- University of North Carolina, Chapel Hill
Diabetic Gastroparesis
Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis
The objective of the study is in subjects with Insulin Treated Diabetes Mellitus type 1 or 2 and gastroparesis: validate radiopaque markers with fluoroscopy with gastric scintigraphy method study the difference of metabolic…
- Trial name
- NCT01557296
- Testing
- dietary treatment: food of small particle size, Validate X-ray diagnostic method., Can the motility be improved
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Hip Fracture, Pain Management
Comparison of the Efficacy of Ultrasound-guided Supra-inguinal Fascia Iliaca and Lumbar Erector Spina Plan Block in Hip Fractures
The aim of our study was to evaluate the efficacy and patient satisfaction level of SI-FIB and lumbar ESPB for positioning and postoperative analgesia during spinal anesthesia in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture, Pain Management, Multimodal Analgesia, Peripheral Nerve Block
- Trial name
- NCT07639762
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Chronic Pain
Analgesia Nociception Index In Pediatric Patients With Chronic Pain
The goal of this observational study is to learn about the analgesia nociceptive index (ANI) is associated with pain sensitivity in patients between the ages of 9-17 who are experiencing chronic pain.
- Trial name
- Chronic pain (NCT07145762)
- Testing
- Interventional Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type2 Diabetes Mellitus
High Protein Effect on Body Composition and Sarcopenia Markers in Older Patients With Type 2 Diabetes Mellitus
This study will investigate the impact of dietary protein intake on progressive muscle loss and functionality (sarcopenia) in older adults with type 2 diabetes mellitus.
- Trial name
- NCT05457088
- Testing
- 1.5 protein, 0.8 protein
- Where
- Greece
- Volunteers
- 25 people
- Sponsor
- National and Kapodistrian University of Athens
Temporomandibular Disorder, Facial Pain
Stabilization Splint Treatment of TMD
The aim of this randomized controlled trial was to assess the efficacy of stabilization splint treatment on TMD-related facial pain and oral health-related quality of life during a one-year follow-up.
- Trial name
- TMD (NCT05240703)
- Testing
- Stabilization splint treatment
- Volunteers
- 80 people
- Sponsor
- University of Oulu
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