Clinical trials: Neurologic Symptoms
Pain
Effect of Dry Needling on Myofascial Trigger Point
Myofascial trigger point is one of the most common causes of musculoskeletal disorders. Myofascial trigger point in upper trapezius has been reported as a symptom in patients with neck and upper thoracic pain.
- Trial name
- NCT02107456
- Testing
- Dry Needling
- Where
- Iran
- Volunteers
- 33 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Hearing Impairment
Clinical Evaluation of the Nuance Audio Hearing Aid in Adults With Mild to Moderate Hearing Difficulties
The research will produce clinical effectiveness performance metrics using standardised procedures of the Nuance Audio hearing device.
- Trial name
- NCT07100522
- Testing
- Hearing aid in spectacle frame form factor, hearing aid
- Where
- Australia
- Volunteers
- 21 people
- Sponsor
- Luxottica Group S.p.A.
Sarcopenia, Muscle Weakness
Effects of Mobility Dose in Surgical Intensive Care Unit Patients
The primary aim of this study is to assess if the mobility dose that patients receive in the surgical intensive care unit (SICU) predicts adverse discharge disposition (primary endpoint), and muscle wasting diagnosed by bedside…
- Conditions
- Sarcopenia, Muscle Weakness, Critical Illness
- Trial name
- MQS (NCT03196960)
- Where
- 3 sites in United States, Germany and 1 more
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Drug-Resistant Epilepsy, Focal-Onset Seizures
Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy
The purpose of the study is to evaluate the long-term safety and tolerability of Padsevonil administered at individualized doses as adjunctive treatment for subjects with drug-resistant epilepsy.
- Trial name
- NCT03370120
- Testing
- Padsevonil
- Where
- 156 sites in United States, Australia and 25 more
- Volunteers
- 406 people
- Sponsor
- UCB Biopharma SRL
Postoperative Pain, Cholecystectomy, Laparoscopic
M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve…
- Trial name
- NCT07403682
- Testing
- Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA), erector spinae plane block (ESPB)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Transcutaneous, Pulsed Radiofrequency
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
The aim of the present study is to compare the analgesic efficacy of combined transcutaneous pulsed radiofrequency plus genicular nerve block with bupivacaine plus corticosteroid versus intraarticular Hyaluronic acid injections…
- Conditions
- Transcutaneous, Pulsed Radiofrequency, Genicular Nerve Block, Intraarticular
- Trial name
- NCT06710782
- Testing
- Hyaluronic acid, Transcutaneous pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Opioid Consumption, Incidence of Nausea and Vomiting
TAP Block for Open Radical Prostatectomy.
This is a prospective, double blind, randomized study is proposed in patients undergoing open radical prostatectomy: its objective is to establish whether continuous bilateral TAP blocks would provide adequate perioperative…
- Conditions
- Opioid Consumption, Incidence of Nausea and Vomiting, Postoperative Pain, Assessment of Recovery
- Trial name
- NCT01157546
- Testing
- Normal saline via TAP catheters, Lidocaine via TAP catheters
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Postoperative Pain, Sternotomy Pain
Comparison of Erector Spinae Plane Block (ESPB) With the Combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) in the Management of Postoperative Sternotomy Pain in Patients Undergoing Cardiac Surgery Via Sternotomy
This study aims to compare the effectiveness of two regional anesthesia techniques in managing pain for participants undergoing cardiac surgery via sternotomy.
- Conditions
- Postoperative Pain, Sternotomy Pain, Acute Pain, Cardiac Surgery
- Trial name
- NCT07472296
- Testing
- Erector spinae plane block (ESPB), Superficial Parasternal Intercostal Plane Block (SPIPB), Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Traumatic Brain Injury, Post-traumatic Stress Disorder
Improving Sleep in Veterans With the Polytrauma Clinical Triad
The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain.
- Conditions
- Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
- Trial name
- LIONv2 (NCT06477796)
- Testing
- Morning Bright Light Therapy, Negative Ion Generator
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Cerebrospinal Fluid Leak
The EVICEL® Neurosurgery Phase III Study
The objective of this study is to evaluate the safety and efficacy of EVICEL® Fibrin Sealant (Human) for use as an adjunct to sutured dural repair in cranial surgery.
- Trial name
- NCT02457546
- Testing
- EVICEL Fibrin Sealant, Hydrogel sealant
- Where
- 26 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Ethicon, Inc.
Aging, Foot Muscle Dysfunction
Effects of Rehabilitative Exergame Training on Foot Muscle Activity, Balance, and Mobility in Older Adults
This study is designed as a randomized controlled trial. A total of 40 healthy older adults residing in private and public nursing homes and rehabilitation centers in Mersin will be enrolled.
- Conditions
- Aging, Foot Muscle Dysfunction, Sarcopenia, Age-Related Muscle Weakness
- Trial name
- EXG-FOOT (NCT07357662)
- Testing
- Exergame-based Balance and Foot Muscle Training, Conventional Functional Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tarsus University
Hyperacusis
Role of Exposure in Hyperacusis
This study focuses on patients with a primary complaint of hyperacusis. Hyperacusis has been defined as 'abnormally reduced tolerance to sound'.
- Trial name
- NCT04705246
- Testing
- Psychoeducation
- Volunteers
- 5 people
- Sponsor
- University Hospital, Antwerp
COVID-19, Headache Disorders
Impact of COVID-19 Pandemic on Headache Evaluations in the Pediatric Emergency Department
Background: To evaluate the impact of COVID-19 on evaluations in the pediatric emergency department (ED) because of headache as main symptom.
- Conditions
- COVID-19, Headache Disorders, Emergency Service, Hospital
- Trial name
- NCT06295003
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Pain
Safety/Efficacy Study of Oxycodone HCl/Niacin to Treat Pain After Bunionectomy
The purpose of this study is to determine whether oxycodone HCl and niacin are effective in the treatment of pain following bunionectomy surgery.
- Trial name
- NCT00654069
- Testing
- Acurox 5/30 mg, Acurox 7.5/30
- Volunteers
- 405 people
- Sponsor
- Acura Pharmaceuticals Inc.
Bertolotti's Syndrome, Lower Back Pain
Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers
The purpose of this study is to collect lumbar rotations, velocity, and accelerations, along with pain scores using a novel dynamic VAS device, from twenty (20) Bertolotti Syndrome patients and twenty (20) non-Bertolotti low back…
- Trial name
- NCT06225583
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Ketamine-Induced Mood Disorder
The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Optimal multimodal opioid-sparing analgesic technique is considered as one of the most important Enhanced recovery pathways (ERPs) or enhanced recovery after surgery (ERAS) interventions that mitigate the undesirable effects of…
- Trial name
- NCT05474183
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Pain
Effects of Simvastatin in the Prevention of Pain Experienced After Tooth Extraction
Atraumatic extraction of maxillary premolar teeth (on the Right, left side) was done; Subsequently, the patients were randomly divided into two equal groups: A group (Extraction + filled with a Simvastatin solution impregnated…
- Trial name
- NCT04406883
- Testing
- Extraction + filled with Simvastatin solution impregnated gelatin sponge
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Bell's Palsy
Mirror Therapy vs Mime Therapy in Bell's Palsy
This randomized controlled trial aims to compare the effectiveness of mirror book therapy and mime therapy in patients with Bell's palsy.
- Trial name
- NCT07716683
- Testing
- Mirror Book Therapy, Mime Therapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore
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