Clinical trials: Neurological; Disorder, Nervous System
Mobility Limitation, Sleep Quality
Use Modular Medical Equipment Vehicle in Mobilization of Patient With Chest Tube
in this study, it was aimed to examine the effect of the modular carrying system on the outcomes of care in the mobilization of patients with a chest tube.
- Conditions
- Mobility Limitation, Sleep Quality, Pain, Comfort
- Trial name
- NCT05081856
- Testing
- mobilization with moduler medical equipment carring vehicle
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Istanbul Medipol University Hospital
Burst Suppression, EEG With Abnormally Slow Frequencies
Reduction of Intraoperative EEG Burst Suppression
Burst suppression (BS) is a not physiological pattern in the electroencephalogram (EEG). BS during general anesthesia is mainly seen as a sign for too deep hypnosis and may increase the risk of postoperative delirium (POD), a…
- Conditions
- Burst Suppression, EEG With Abnormally Slow Frequencies, Postoperative Delirium
- Trial name
- BsR (NCT03775356)
- Testing
- Treatment of hypotension and/or reduction of anesthetics
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- Technical University of Munich
Headache
Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache
The purpose of this study is to determine whether prednisolone is more effective than placebo in the first six days after initiation of medication withdrawal therapy for a medication overuse headache.
- Trial name
- NCT00135122
- Testing
- prednisolone
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sorlandet Hospital HF
Sarcopenia
Effect of Ishige Okamurae Extract on Musculoskeletal Biomarkers in Adults With Relative Sarcopenia
The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of Ishige Okamurae extracts on muscle strength, muscle mass, and muscle function in adults with relative sarcopenia for 12…
- Trial name
- NCT04617951
- Testing
- Ishige Okamurae extracts group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Hearing Loss
Assessment of Novel Measurement and Fitting Methods to Determine Their Reliability, Validity and Application - Sonova2018_34
A methodical evaluation of novel measurement and fitting methods for individualizing CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- NCT03755453
- Testing
- Hearing aid: Phonak Audéo B90-Direct
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Sonova AG
Hypogonadism, Diabetes
Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.
Background: Men≥65 years often produce lower levels of testosterone, meaning there is less testosterone circulating to the tissues of the body.
- Conditions
- Hypogonadism, Diabetes, Sarcopenia, Osteoporosis
- Trial name
- NCT00104572
- Testing
- Androgel (Testosterone Gel), Anastrozole (Aromatase Inhibitor), Calcium Cardone 500mg with vitamin D 400 IU
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Cerebrospinal Fluid Leaks
A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for Treatment
The goal of this randomized controlled trial (RCT) is to compare the efficacy of CT fluoroscopy-guided targeted epidural patching for treatment of imaging-confirmed spinal CSF leaks to that of a simulated procedure without…
- Trial name
- NCT03276975
- Testing
- TISSEEL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Memory Impairment, Sleep Disorder
Improving Patient Memory for Treatment for Mild Cognitive Impairment
The main empirical question to be addressed is: What types of memory support are most potent for patients who are experiencing a mild cognitive impairment (MCI) relative to non-MCI patients?
- Trial name
- NCT05668481
- Testing
- Transdiagnostic sleep and circadian intervention (TranS-C)
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Epilepsy, Status Epilepticus
Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus
Status epilepticus (SE) is an acute and critical form of neurological and systemic diseases involving multiple clinical disciplines, with an annual incidence of (20-73) per 100,000 people and a clinical case fatality rate of 20%.
- Trial name
- NCT06966830
- Testing
- Lacosamide (LCM)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Analgesia
Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery
This study aimed to compare the efficacy of high thoracic-ESPB with shoulder block as analgesic options for arthroscopic shoulder surgery. Primary outcome: 24-hour analgesic consumption.
- Trial name
- NCT06202430
- Testing
- High Thoracic Erector Spinae Plane Block, Shoulder Block
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Spinal Cord Injuries, Spinal Cord Injury Cervical
Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System
This is a single-cohort early feasibility trial to determine whether an investigational device called the Bidirectional Neural Bypass System can lead to the restoration of movement and sensation in the hand and wrist of up to…
- Trial name
- NCT03680872
- Testing
- Bidirectional Neural Bypass System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Chad Bouton
Neurologic Manifestations
Cannulation of the Artery Axiliaris for Extracorporeal Circulation
Comparision of two different cannulation techniques on the neurological outcome in cardiac surcical procedures. Study hypothesis: Cannulation of the axilaris artery can reduce neurolocical side effects.
- Trial name
- NCT01615172
- Testing
- cannulation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Cognitive Impairment, Dementia
Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study
The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with…
- Conditions
- Cognitive Impairment, Dementia, Delirium, Functional Decline
- Trial name
- OASIS (NCT06150339)
- Testing
- OASIS Walking Intervention
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Low Muscle Strength, Malnutrition
Efficacy of Oral Nutritional Supplement in Community-Dwelling Adults Following Acute Care
The study aims to determine the effects of Oral Nutritional Supplement (ONS) added to usual care on body weight compared with usual care alone in community-dwelling adults aged 55 years and older who are at risk of malnutrition…
- Trial name
- NCT07753239
- Testing
- ONS, Standard of Care (SOC)
- Where
- 7 sites in Thailand
- Volunteers
- 304 people
- Sponsor
- Abbott Nutrition
Cluster Headache
High Dose Vitamin D Plus Multivitamin in the Prevention of Cluster Headache
This study intends to investigate the use of high-dose Vitamin D3 plus a multivitamin in the prevention of cluster headache attacks.
- Trial name
- NCT04570475
- Testing
- Vitamin D, multivitamin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cervicogenic Headache, Neck Pain
Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study
This study is designed to collect normative data on cervical isometric strength and range of motion to supplement an existing normative data base.
- Conditions
- Cervicogenic Headache, Neck Pain, Whiplash, Kyphotic and Reversed Cervical Curves
- Trial name
- NCT00510757
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Ephedrine, Norepinephrine
Postoperative Delirium After Intraoperative Ephedrine Versus Norepinephrine
This retrospective study aims to investigate the effects of norepinephrine compared to ephedrine, administered on the day of surgery, on the incidence of postoperative delirium.
- Conditions
- Ephedrine, Norepinephrine, Postoperative Delirium (POD)
- Trial name
- NCT06844201
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 10,000 people
- Sponsor
- Riverside University Health System Medical Center
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Brain Injuries, Multiple Sclerosis
Evaluation of an Acceptance and Commitment Therapy Group for Adjustment Difficulties in Neurological Conditions
With an increase of over 38% in neurological related hospital admissions between 2008-13, there are now over 12.5 million cases of individuals with neurological conditions in the UK.
- Conditions
- Brain Injuries, Multiple Sclerosis, Parkinson Disease, Stroke
- Trial name
- NCT02454465
- Testing
- Acceptance and Commitment Therapy group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Hertfordshire
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.