Clinical trials: Neurological Complication
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova
Premature, Pneumonia
Respiratory Physiotherapy Change Premature Pain With Pneumonia
Objective to evaluate the effects of vibration techniques and acceleration of expiratory flow on pain parameters in preterm infants diagnosed with pneumonia hospitalized in the Intensive Care Unit and Neonatal Intermediate Care…
- Conditions
- Premature, Pneumonia, Pain, Physiotherapy
- Trial name
- RPCPPWP (NCT03027206)
- Testing
- Vibration technique, Acceleration of expiratory flow
- Volunteers
- 28 people
- Sponsor
- Amazon University
Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute
The Use of a Comfort Tote to Improve Recovery in Pediatric and Adolescent Patients After Surgery
The goal of this clinical trial is to learn if the use of Comfort Tote can treat pain and anxiety in adolescents with idiopathic scoliosis undergoing posterior spinal fusion. The study aims to answer two questions: 1.
- Conditions
- Adolescent Idiopathic Scoliosis, Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- NCT07632833
- Testing
- The Therapeutic Comfort Tote, The Modified Comfort Tote
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Postoperative Nausea and Vomiting, Postoperative Pain
Acupuncture for Postoperative Nausea, Vomiting and Pain in Children: The Implication of Parental Attitudes
Postoperative nausea and vomiting (PONV) remain a significant challenge in our practice. However, pharmaceutical prophylaxis is only partially effective and can imply unpleasant adverse effects.
- Trial name
- NCT01729052
- Testing
- Acupuncture
- Volunteers
- 282 people
- Sponsor
- University of Tromso
Sarcopenia, Cancer
Effect of Oral Protein Supplementation on Postoperative Complications in Elderly Sarcopenic Cancerous Patients
Sarcopenia is a condition of reduced skeletal muscle associated with aging. It leads to poor outcome and increased risk of postoperative complications.
- Trial name
- NCT04306562
- Testing
- enteral nutrition supplement
- Where
- Thailand
- Volunteers
- 5 people
- Sponsor
- Siriraj Hospital
Surgery, Pain, Postoperative
Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy
Local intra-articular injection of anesthetics (LIA) is increasingly used during knee arthroscopy for pain relief. The LIA can only be performed at the end of surgery as the knee joint is continuously flushed during the…
- Conditions
- Surgery, Pain, Postoperative, Nausea, Postoperative, Opioid Use
- Trial name
- NCT03599427
- Testing
- systemic lidocaine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Knee Replacement, Total, Pain, Postoperative
Function, Pain, and Alignment Following Knee Replacement for the Treatment of Osteoarthritis
There are many factors that can influence patient satisfaction and patient related outcomes following total knee replacement including the surgical alignment of the joint components.
- Conditions
- Knee Replacement, Total, Pain, Postoperative, Functional Independence
- Trial name
- NCT05490186
- Testing
- Total Knee Replacement
- Where
- Canada
- Volunteers
- 261 people
- Sponsor
- North York General Hospital
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Postoperative Pain
Assessment of Postoperative Pain Following Root Canal Obturation of Permanent Mature Teeth Using Three Different Obturation Techniques: A Randomized Clinical Trial
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of…
- Trial name
- NCT07863622
- Testing
- Cold Lateral condensation technique, Vibration thermo-dynamic technique, Injection of thermo-plasticized gutta-percha
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Pain Postoperative
Foraminal Enlargement and Postoperative Pain.
The purpose of this study is to determine whether enlarging the apical foramen causes postoperative pain in teeth with necrotic pulp and apical periodontitis.
- Trial name
- NCT02770053
- Testing
- Foraminal enlargement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Postoperative Pain
Parental Self-Efficacy for Child Autonomy and Postoperative Pain in Children Undergoing Minor Surgery
This study aims to examine the relationship between parental self-efficacy in supporting child autonomy and postoperative pain levels in children undergoing minor surgical procedures.
- Trial name
- PSE-PAIN-MS (NCT07381673)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Agri Ibrahim Cecen University
Knee Replacement, Postoperative Pain
Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty
The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods.
- Conditions
- Knee Replacement, Postoperative Pain, Opioid Use
- Trial name
- NCT04314505
- Testing
- Opioid-Sparing Protocol, Opioid-Based Patient Controlled Analgesia
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pain, Postoperative
Dexmedetomidine Reduce Postoperative Pain of C-section
The purpose of this study was to make sure whether the infiltration of dexmedetomidine around the uterus can reduce the pain of cesarean section surgery.Studies have shown that the use of local anesthetic infiltration around the…
- Trial name
- NCT05622656
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Post Operative Pain
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by…
- Trial name
- NCT06349772
- Testing
- Zynrelef, Exparel
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Ambulatory Surgery, Laparoscopy
Implementation of 23 Hour Surgery Model in a Tertiary Hospital
Extended day surgery or 23 h surgery (23-hour surgery) is a surgical model where patients arrive to the hospital from home at the day of surgery, are operated and recover in a 23 h surgery unit.
- Conditions
- Ambulatory Surgery, Laparoscopy, Shoulder Impingement Syndrome, Ovarian Cysts
- Trial name
- Herko (NCT04142203)
- Testing
- 23 h surgery
- Where
- Finland
- Volunteers
- 993 people
- Sponsor
- Kuopio University Hospital
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Inguinal Herniorrhaphy, Pain, Postoperative
Post-Operative Analgesic Effects of Local Wound Infiltration With Ketorolac After Inguinal Herniorrhaphy
Inguinal hernia is one of the most common diseases worldwide, including Thailand. Patients who underwent treatment of inguinal hernia (herniorrhaphy) found surgical site pain.There are many procedures to relieve pain after…
- Trial name
- NCT03534505
- Testing
- Ketorolac group, Bupivacaine group
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Failed Back Surgery Syndrome
A Novel Approach in Spinal Cord Stimulation: a Combination of Burst and Tonic Waveforms.
Spinal Cord Stimulation (SCS) has been a well-established treatment for chronic neuropathic pain in Failed Back Surgery Syndrome with associated legs and/or low back pain.
- Trial name
- NCT03201705
- Testing
- Burst + Tonic
- Volunteers
- 10 people
- Sponsor
- Massimo Innamorato
Brain Tumor, Brain Metastases
Re-craniotomy and Complications After Elective Neurosurgery
This study is a prospective cohort study to find the incidence of re-craniotomy and predictive factors. The secondary outcomes are to find the incidence of major non-neurological complications and predictive factors.
- Conditions
- Brain Tumor, Brain Metastases, Brain Cancer, Brain Neoplasms
- Trial name
- NCT03910556
- Testing
- Propofol
- Volunteers
- 439 people
- Sponsor
- Chiang Mai University