Clinical trials: Neurological Complications
Postoperative Pain
Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies
TAPA is a new analgesic block technique that involves the injection of local anesthetics into the thoracoabdominal nerves using a perichondrial approach.
- Trial name
- NCT06116409
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain, Postoperative
Analgesic Effect of Three-point Transversus Abdominis Plane Block Compared With Continuous Epidural Infusion for Post-laparoscopic Nephrectomy
This study aimed to compare the efficacy three-point Transversus Abdominis Plane (TAP) blocks with continuous epidural infusion for alleviating pain post-laparoscopic nephrectomy
- Trial name
- NCT03154463
- Testing
- TAP Blocks, continuous epidural infusion
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Chronic Post Operative Pain
Prevalence and Risk Factors for Postsurgical Pain After the Open Reduction and Internal Fixation of Lower Limbs.
The objective of this study is to specify the demographic and medical factors that most likely constitute a risk of developing CPSP in the patients with lower limb.
- Trial name
- NCT06136663
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
WAGR Syndrome, Wilm's Tumor
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions
This study will explore conditions caused by the absence of certain genes on chromosome 11. These conditions include WAGR syndrome, which is characterized by a kidney tumor called Wilm s tumor, aniridia (absence of the iris of…
- Conditions
- WAGR Syndrome, Wilm's Tumor, Aniridia, Urogenital Abnormalities
- Trial name
- NCT00758108
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Weight, Birth, Premature Birth
Effects of Olfactory and Gustatory Stimulus on the Nutrition of Premature Babies
The objective of this clinical trial is to test the effects of olfactory and taste stimulation with milk or water in premature newborns with a gestational age between 28 and 32 weeks.
- Trial name
- NCT06305052
- Testing
- Milk, Water
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Root Canal Treatment
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
The objective of this research was to identify which of the root canal sealers, AH Plus or WellRootST, yielded more effective outcomes regarding postoperative pain when applied to teeth diagnosed with apical periodontitis.
- Trial name
- NCT07246174
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Postoperative Pain
Effect of Preemptive Intramuscular Diclofenac on Minimal Effective-Dose Bupivacaine Saddle Block for Minor Perianal Surgeries
The research will be carried out in order to test the effect of Intramuscular (IM) Diclofenac, administered as preemptive analgesic with minimal effective dose spinal anesthesia in perianal surgeries, on prolonging the time to…
- Trial name
- NCT04849468
- Testing
- Declofenac, saline
- Where
- Saudi Arabia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Pain, Postoperative
The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Dexamethasone is one of many adjuncts tested to prolong the duration of spinal anesthesia and its analgesic effect. The intent of this, a single-site, double-blinded, randomized controlled trial, is to determine if a single…
- Trial name
- NCT04624360
- Testing
- Dexamethasone
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postoperative Pain
Can the Different Instruments Used ın Root Canal Treatment Have an Effect on Postoperative Pain?
Root canal treatment is a treatment method in which the pulp is irreversibly infected due to caries or trauma or when the pulp loses its vitality.
- Trial name
- NCT05927025
- Testing
- Hand K-files
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hysterectomy, Myomectomy
Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery
Postoperative pain continues to be inadequately managed and is the most common reason for the delay in discharge and unplanned hospital admission after surgery. Opioids remain the mainstay for postoperative analgesia.
- Trial name
- NCT03363425
- Testing
- Lidocaine Iv, Dexmedetomidine, Normal saline
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Postpartum Anxiety, Postpartum Depression
Postpartum Screening for Anxiety and Comorbid Conditions
The goal of this project is to facilitate the design of individualized postpartum anxiety (PPA) screening strategies in British Columbia (BC), Canada.
- Conditions
- Postpartum Anxiety, Postpartum Depression, Postpartum Disorder, Postoperative Pain
- Trial name
- PPA (NCT06242717)
- Where
- Canada
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Postoperative
Post Operative Pain Management for ACL Reconstruction
Health care providers are seeking methods to limit post-operative pain and opioid prescriptions to reduce the burden of the national opioid use epidemic.
- Trial name
- NCT05316168
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone, Infiltration between Popliteal Artery and Capsule of the knee (iPACK)
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Chronic Pain, Pain Measurement
Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Syndrome (PMPS)
This is a retrospective, observational study which will utilise the Edinburgh Cancer Research Centre's Tissue Bank to provide samples for IENFD testing in those who have undergone mastectomy surgery for breast cancer.
- Conditions
- Chronic Pain, Pain Measurement, Mastectomy, Postoperative Pain
- Trial name
- NCT02919891
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Infant Development, Premature
Hammock Position and Kangaroo Care
This study was planned to evaluate the effectiveness of two positions that may have an effect on pain, stress, comfort and physiological parameters in premature infants.
- Trial name
- NCT06436404
- Testing
- Hammock intervention, Kangaroo care intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
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