Clinical trials: Neurological Condition
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Pain, Pain Measurement
Relationship of Intra-Epidermal Nerve Fibre Density (IENFD) and Structure to Chronic Post-Mastectomy Pain Syndrome (PMPS)
This is a retrospective, observational study which will utilise the Edinburgh Cancer Research Centre's Tissue Bank to provide samples for IENFD testing in those who have undergone mastectomy surgery for breast cancer.
- Conditions
- Chronic Pain, Pain Measurement, Mastectomy, Postoperative Pain
- Trial name
- NCT02919891
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Vaccination; Complications, Vaccine Adverse Reaction
Effectiveness of CARD for Improving School-Based Immunizations
Vaccination is estimated to have saved more lives in Canada than any other single intervention and is considered one of the most important advances in the prevention of disease.
- Conditions
- Vaccination; Complications, Vaccine Adverse Reaction, Fear
- Trial name
- NCT03966391
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 8,839 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Renal Colic
Acupuncture Versus IV Morphine in the Treatment of Acute Pain in ED
Renal colics are a common cause af acute intense pain in medical emergency settings requiring often the use of high level antalgics (opioid) to relief the patient.
- Trial name
- AcuMoPE (NCT02152410)
- Testing
- acupuncture, Morphine
- Where
- 2 sites in Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Post Operative Pain, Distal Radius Fracture
Low Dose Dexamethasone for Distal Radius Fractures
The addition of the steroid dexamethasone to a single injection of local anesthetic has been shown to significantly prolong the duration of peripheral nerve blockade compared to local anesthetic alone.
- Trial name
- NCT05274113
- Testing
- Dexamethasone 4mg, Ropivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Childbirth, Pain
Mental Training and Childbirth
Labour pain is a challenge to the parturient woman. Pain relief methods during birth are limited and often associated with side effects.
- Trial name
- NCT00914082
- Testing
- Self hypnosis
- Where
- Denmark
- Volunteers
- 1,222 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pain, Neuropathic, Neuropathic Pain
Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects
This study is being conducted to assess the effects of GSK1014802 and a positive control, lidocaine, on tests of peripheral nerve excitability. This will be a double blind, placebo controlled, 4-period cross over study.
- Trial name
- NCT00964288
- Testing
- GSK1014802 low dose, Lidocaine, GSK1014802 high dose
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Biogen
Stuttering, Adult
Information Processing Biases in Adults Who Stutter
The goal of this clinical trial is to examine whether stuttering is associated with a tendency to attend more quickly or for longer durations to threat-related information in the environment (threat-related attention bias).
- Trial name
- NCT06422442
- Testing
- Threat-related stimulus exposure
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Period Pain
Impacts of Static Magnetic Fields on Dysmenorrhea Pain
Study to determine the effectiveness of a certain type of magnet to reduce period pain
- Trial name
- NCT04539691
- Testing
- Magnet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Pain
Correlation of Pain Intensity Measurements in Healthy Volunteers Exposed to Unpleasant Stimuli
Pain is an unpleasant sensory and emotional phenomenon that can be caused by tissue damage or potentially harmful stimuli. Pain is by definition a subjective phenomenon, and everyone experiences it differently, which creates…
- Trial name
- NCT06663761
- Testing
- Stimuli
- Where
- Poland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Dyslexia
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia
The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children. The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard…
- Trial name
- EQUIDYS (NCT02879786)
- Testing
- Posturographic tests, Questionnaire of motion sickness susceptibility
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Shoulder Arthroplasty
Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants
The purpose of this study is to determine whether the use of plain bupivacaine with common adjuvants for interscalene block (ISB) provides non-inferior analgesic results compared to the use of liposomal bupivacaine for ISB, in…
- Trial name
- NCT03845894
- Testing
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injury
Development of a Model of Shoulder Pain Following Spinal Cord Injury
This study will investigate the progression of musculoskeletal (shoulder muscle flexibility, muscle strength, movement coordination, and rotator cuff health) and psychosocial (fear of movement, pain catastrophizing) impairments…
- Trial name
- NCT03137394
- Testing
- Observation
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Drexel University
Sleep Deprivation, Pain
Mechanisms of Sleep Disruption Hyperalgesia
Twenty percent of Americans suffer from chronic pain. Sleep disturbance is similarly prevalent and among the most common and disabling neurobehavioral problems associated with chronic pain.
- Trial name
- ESP2 (NCT01794689)
- Testing
- Morphine, Forced Awakenings, Uninterrupted Sleep
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Spinal Cord Injury, Able Bodied
Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury
Spinal cord injury (SCI) is a highly debilitating pathology, associated with the loss of sensorimotor functions, autonomy and quality of life.
- Conditions
- Spinal Cord Injury, Able Bodied, Traumatic Spinal Cord Injuries, Paraplegia, Spinal
- Trial name
- NCT07732868
- Testing
- Brain-Machine Interface
- Where
- 2 sites in Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- José Gabriel da Silva Figueiredo
Orofacial Pain, Bruxism
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
To evaluate the clinical effectiveness of chlorzoxazone in comparison to orphenadrine Citrate in relieving the orofacial pain in bruxers.
- Trial name
- NCT07109882
- Testing
- Chlorzoxazone, Orphenadrine Citrate
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Post Operative Pain, Nausea and Vomiting, Postoperative
ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery
This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT05805423
- Testing
- bilateral superficial cervical plexus blocks and local wound infiltration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Chest Pain
Low-Risk Chest Pain Echo Study
Pilot study to assess if a bedside point-of-care echocardiogram performed on emergency department patients identified as low-risk chest pain prior to discharge significantly changes patient disposition or follow up instructions.
- Trial name
- NCT05785923
- Testing
- Point-of-Care Echocardiogram
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.
- Conditions
- Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome, Duane Radial Ray Syndrome, Mobius Syndrome
- Trial name
- NCT03059420
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
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