Clinical trials: Neurological Condition
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
fNIRS for Disorders of Consciousness
The goal of this observational study is to learn whether functional near-infrared spectroscopy (fNIRS) can measure brain activity in healthy adults and in people with disorders of consciousness (DoC) in the neuro-intensive care…
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State
- Trial name
- NCT07485361
- Testing
- Functional Near-Infrared Spectroscopy Monitoring
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Ehlers-Danlos Syndrome (EDS)
Impact of Ehlers-Danlos Syndrome on Gynaecological Health
Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain.
- Trial name
- GYNESED (NCT07151274)
- Where
- France
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Postoperative Pain, Postoperative Return of Bowel Function
Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Sections
Postoperative discomfort is a frequently seen adverse event after to caesarean operation. Early mobilization and bonding of the mother and her infant are typically impacted by this phenomenon.
- Trial name
- NCT06433713
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trigger Point Pain, Myofascial
Comparison of High Power Pain Threshold Ultrasound and Ischemic Compression Techniques for Treatment of Trigger Points
This study aimed to compare the efficacy of ischemic compression and two different application methods of high power pain threshold ultrasound techniques on latent trigger point treatment.
- Trial name
- NCT04823013
- Testing
- high power pain threshold ultrasound which the dose was kept constant, high power pain threshold ultrasound which the dose reduced to one half, ischemic compression
- Where
- Turkey (Türkiye)
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Gazi University
Unconscious, Inflammation
Volume Kinetics for 20% Albumin in Different Clinical Situations
The study aims to determine the degree of plasma volume expansion and the half-life of the plasma volume expansion when 3 mL/kg of hyperoncotic (20%) albumin if infused over 30 minutes in conscious healthy volunteers, in patients…
- Trial name
- Albumin (NCT02556580)
- Testing
- Albumin 20%
- Where
- 2 sites in Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sodertalje Hospital
Electromyography, Eye-tracking
Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects
The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials.
- Conditions
- Electromyography, Eye-tracking, Facial Palsy
- Trial name
- AQ2MF (NCT05581680)
- Testing
- dental impressions, Simultaneous MoCap and EMG acquisition, Eye-tracking acquisition for pathological subjects
- Where
- France
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Pain
Efficacy of Co-administration of an NSAID With a Dopamine Agonist In Healthy Subjects
Findings from the investigator's lab and others' show the involvement of the brain's mesolimbic circuitry in pain perception and evaluation, as well as during the transition from acute to chronic pain states in both humans and…
- Trial name
- NCT02116790
- Testing
- Naproxen, Sinemet
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Anosmia, Asymptomatic COVID-19
Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19).
- Conditions
- Anosmia, Asymptomatic COVID-19, COVID-19 Respiratory Infection, Influenza
- Trial name
- NCT05040659
- Testing
- AROMHA Longitudinal Smell Test
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pain, Cesarean Section
Intrathecal Hydromorphone for Pain Control After Cesarean Section
The use of intrathecal opioids for analgesia in the setting of cesarean section has become standard obstetric anesthesia practice. Currently, two opioids are commonly used. These opioids are fentanyl and morphine (Duramorph).
- Trial name
- NCT02096003
- Testing
- Intrathecal morphine, Intrathecal hydromorphone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Low Back Pain
Active Management for Low Back Pain for 6 to 8 Year Old Schoolchildren
The objective is to assess the effectiveness of a prevention campaign promoting active management in shifting beliefs in 6 to 8 year old schoolchildren.
- Trial name
- NCT00809640
- Testing
- Education (Back Comic-Book)
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kovacs Foundation
Chronic Low-back Pain
The Effect of Physiotherapy on Chronic Low Back Pain
Demographic data of patients diagnosed with chronic low back pain and planned for medical treatment (n:30) and physical therapy in addition to medical treatment (n:30), as well as before and after treatment; Visual analog scale…
- Trial name
- NCT06234891
- Testing
- Nsaid, Phsiotheraphy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hearing Loss, Unilateral
Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
This feasibility study evaluates whether children with unilateral, moderate to profound sensorineural hearing loss experience an improvement in speech perception, hearing in noise, localization, and quality of life with a…
- Trial name
- CIPUHL (NCT02963974)
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ultrasound Guided Rectus Sheath Block, Pain, Postoperative
Comparison Between Ultra Sound Guided Rectus Sheath Block and Field Block for Midline Hernia Repair
Randomized double blinded controlled clinical trial will be done with a total number of 75 patients will be divided into 3 groups.
- Trial name
- NCT03225313
- Testing
- Bupivacaine Hydrochloride 0.5% Injection Solution_#4, Normal Saline Flush, 0.9% Injectable Solution_#5
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Hypertrophy, Sensation Disorders
Postural Control in Breast Hypertrophy
Principles of motor control suggest that breast hypertrophy can lead to sensoriomotor alterations and impairment in body balance due to postural misalignment.
- Trial name
- NCT01519024
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Pelvic Pain
Infiltrations With Collagen in Episiotomy and Cesarean Scars
One of the causes of pelvic pain is secondary to scarring due to episiotomy or cesarean after delivery.The pain of episiotomies or cesarean scars can be generalized at the level of the perineum, or more specifically at the level…
- Trial name
- NCT04112888
- Testing
- Collagen, Rehabilitation sessions
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Meniscus Tear, Quality of Life
Evaluation Of Pain, Balance, Functional Performance and Quality of Life in Patients With Meniscus Lesions
Meniscal tears are common knee injuries, affecting a wide demographic from young athletes to the elderly population, often resulting from traumatic sports-related incidents or degenerative processes associated with aging.
- Trial name
- NCT06446973
- Testing
- 35 patients with meniscus tear
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Deafness Neurosensory
Real-time Artificial Intelligence-based Speech Enhancement Methods for Hearing Aid Improvement
Individuals with Auditory Neuropathy Spectrum Disorders (ANSD) represent 1-10% of adults with hearing loss. These individuals have little or no benefit from current hearing aids because ANSD is a continuum of hearing impairments…
- Trial name
- REFINED (NCT05985473)
- Testing
- audiological measurements, Objective and subjective audiological measurements, Evaluation of the denoising methods REFINED
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Neuropathic Pain, Cortical Excitability
Analysis of Cortical Excitability in Neuropathic Pain
The purpose of this study is to determine whether patients with neuropathic pain has abnormal excitability in somatosensory cortex and abnormal sensory-motor connections.
- Trial name
- NCT00789347
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Febrile Seizure
Value of Von Willebrand Factor and Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital
Febrile seizures are one of the most common clinical diseases in pediatric neurology. It occurs between 6 months and 6 years of age and occurs in ~2-5% of children.
- Trial name
- NCT05008458
- Testing
- von willebrand factor and copeptin
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
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