Clinical trials: Neurological Condition
Elderly, Muscle Loss
Effect of Lactobacillus Paracasei PS23 on Improving Aging and Muscle Loss in the Elderly
This study refers to the supplementation of PS23 in human experiments to help the elderly maintain muscle mass, delay muscle loss, promote physical activity, and delay the occurrence of disability and debilitation in elderly…
- Conditions
- Elderly, Muscle Loss, Depression, Anxiety
- Trial name
- NCT06062472
- Testing
- Probiotics, heat-treated of Lactobacillus paracasei HT-PS23
- Where
- Taiwan
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Chi-Chang Huang
Tinnitus, Hearing Loss
Investigating Disinhibitory Brain Mechanism in Tinnitus and Hearing Loss
Tinnitus, the perception of sound in the absence of an external acoustic stimulus. Tinnitus is often perceived inside the head rather than the ear and is a common condition with a prevalence estimated between 10 and 15% in…
- Trial name
- IGNITE (NCT04862572)
- Testing
- MRI scanning
- Where
- 3 sites in United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Female, Older Adults
Effect of Green Tea Supplementation in Older Adult Women
Introduction: One of the consequences of aging is the decrease in physical performance which can affect the quality of life of older people.
- Conditions
- Female, Older Adults, Sarcopenia
- Trial name
- GTAW (NCT06289439)
- Testing
- Green tea (Camellia sinensis) 1000 mg as extract
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Unilateral Deafness
Evaluation of BiCROS Fitting Benefits
22 candidates for BiCROS hearing aids will be recruited and fitted with a hearing aid and a CROS device. Following a real-world trial, each participant will be tested on a range of outcome measures including speech recognition in…
- Trial name
- NCT05379231
- Testing
- Hearing aid fitting
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Auditory Perception; Abnormal, Hearing Loss, Sensorineural
Listening Effort in Cochlear Implant Users
People with hearing loss experience extra effort when listening, which can lead to severe psychological barriers to communication and social participation.
- Conditions
- Auditory Perception; Abnormal, Hearing Loss, Sensorineural, Hearing Loss
- Trial name
- NCT06516575
- Testing
- sentence manipulations
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Procedural Sedation and Analgesia
Combined Ketamine/Propofol for Emergency Department Procedural Sedation
Introduction Numerous drugs and combinations of drugs are used for procedural sedation and analgesia (PSA) in Emergency Departments, including propofol, ketamine, benzodiazepines, narcotics, barbiturates, and others, but propofol…
- Trial name
- NCT01126957
- Testing
- Ketamine, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Complex Regional Pain Syndrome, Sciatica
[18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica
Chronic pain can result from injured or inflamed nerves, as occurs in people suffering from sciatica and CRPS. These nerve injuries or regions of nerve irritation are often the cause of pain in these conditions, but the current…
- Trial name
- NCT02753101
- Testing
- [18F]-FTC-146
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Osteoporosis, Sarcopenia
Bone Microstructure by Using HR-pQCT in Long Courses After Gastrectomy
Osteoporosis after gastrectomy, which is characterized by both the loss of bone mass and the deterioration of bone architecture, is a serious complication in the long course after gastrectomy.
- Conditions
- Osteoporosis, Sarcopenia, Gastric Cancer
- Trial name
- NCT03251430
- Testing
- gastrectomy
- Where
- Japan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Kobayashi Shinichiro
Spinocerebellar Ataxia Type 3
Identification of Biomarkers in Spinocerebellar Ataxia 3
The purpose of this study is to examine the differences in cerebral spinal fluid (CSF) and blood of patients with spinocerebellar ataxias and healthy volunteers.
- Trial name
- SCA3 (NCT03885167)
- Testing
- Specimen Collection
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sudden Sensorineural Hearing Loss, Tinnitus
The Development of Tinnitus in Patients With SSNHL: Insights From fMRI and Metabolomics
The goal of this clinical trial is to investigate the factors and mechanisms underlying tinnitus generation and chronification in patients with sudden sensorineural hearing loss (SSNHL) .
- Trial name
- NCT06355102
- Testing
- Conventional treatment and care
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Aging, Addiction
Based-virtual Reality Diagnosis for Neuropsychiatric Diseases and Sleep/Wake Disorders
The objective of this research is to develop original virtual reality scenarios and/or new virtual reality equipments to evaluate or diagnose pathologies, such as attention deficit disorders or neuropsychiatric pathologies…
- Conditions
- Aging, Addiction, Attention Deficit Disorder With Hyperactivity, Sleep Disorders
- Trial name
- PHENOVIRTPSY (NCT02544295)
- Testing
- Clinical interview, Virtual reality task
- Where
- France
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Pain, Postoperative
Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy
The investigators will assess how the use of toradol and pregabalin affects return to bowel function and see if there is a difference in length of hospital stay.
- Trial name
- NCT03669081
- Testing
- Ketorolac, Pregabalin, Saline
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Voice Disorders
Testing a Smart Phone App to Enhance Voice Therapy Adherence
The current project is designed as phase 1 study conducted to improve/enhance normal voice. Fifteen Thirty non-treatment seeking individuals, with no identifiable vocal pathology on laryngeal examination, will be randomized to…
- Trial name
- NCT04002336
- Testing
- Traditional Voice therapy, Voice Therapy App
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Vrushali Angadi
Post Operative Pain
Dexamethasone vs Dexmedetomidine in Sphenopalatine Ganglion Block for Rhinoplasty Pain
This study will test the effect of adding dexamethasone versus dexmedetomidine as adjuvants to bupivacaine in sphenopalatine ganglion block used for pain after rhinoplasty
- Trial name
- NCT07380139
- Testing
- Dexamedomedine, Dexamethasone, Bubpivacaine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sarcopenia
Evaluation of Sarcopenia in Women in Different Stages of Life and in Hormonal Therapy or Not
The three-year interventional study has the following objectives: The study aims to assess the prevalence of sarcopenia in menopausal women receiving hormone replacement therapy or not compared with pre-menopausal women.
- Trial name
- NCT06792201
- Testing
- SARC-F, Handgrip test, Chair stand test
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Post-operative Pain, Retreatment
Evaluation of Postoperative Pain After Single Visit Retreatment of Symptomatic and Asymptomatic Teeth
Introduction: The aim of this study comparing the post operative pain after the retreatment of asymptomatic and symptomatic teeth that during single visit treatment with rotary and reciprocal nickel titanium files.
- Conditions
- Post-operative Pain, Retreatment, Symptomatic Periapical Periodontitis, Endodontic Disease
- Trial name
- Endodontics (NCT06357481)
- Testing
- Endodontic Retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Post Operative Pain, Inflammation
Clinical and Biochemical Effects Of Cryotherapy Protocols On Mandibular Premolars With Symptomatic Apical Periodontitis
Pain is the major reason for patients' visits to dental clinics.Medications have side effects. Treatments including cryotherapy have been suggested to prevent these side effects.This study will compare the effect of oral and…
- Trial name
- NCT07138365
- Testing
- oral Cryotherapy, Intra radicular Cryotherapy, cold irrigation
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
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