Clinical trials: Neurological Condition
Pain
Incidence of Flare-ups and Apical Healing After Single-visit or Two-visits Treatment.
Aim to compare Incidence of flare-ups and apical healing after single-visit or two-visits treatment of teeth with necrotic pulp and apical periodontitis after a two-year control period.
- Trial name
- FlareUp (NCT02815189)
- Testing
- Ibuprofen for post operative pain, Acetaminophen 325 mg for Flare up
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Analgesia, Epidural, Instrumental Delivery
The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)
The objective of the study: to assess the impact of a proactive policy of offering EA at the start of labour as compared to a restrictive policy or care as usual.
- Conditions
- Analgesia, Epidural, Instrumental Delivery, Maternal Outcome, Neonatal Outcome
- Trial name
- TREAT (NCT01261689)
- Testing
- Ropivacaine/ Sufentanil according to local hospital protocol, Care-as usual pain treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Nerve Pain
Objective Assessment of Sensory Nerve Fiber Sensitivity
This pilot study utilizes a unique technology to determine nerve fiber sensitivity. This will allow us to determine whether this method and device can discern changes in pain intensity and type, which is predicated on differing…
- Trial name
- NCT03596489
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Julia Finkel
Care Giving Burden, Dementia
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia.
- Conditions
- Care Giving Burden, Dementia, Chronic Pain, Pain Management
- Trial name
- PACE-app (NCT07032350)
- Testing
- Web-based pain management support tool, Usual Pain Management Care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Spinal Cord Injury
Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury
The purpose of this study is to determine whether the novel treatment of transcranial direct current stimulation (tDCS) could decrease the pain perception of those with spinal cord injury.
- Trial name
- NCT01112774
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Cavernous Malformation, Cerebral, Cavernous Angioma
Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy
Cerebral cavernous malformation (CCM)-related epilepsy (CRE) impairs the quality of life in patients with CCM. Patients could not always achieve seizure freedom after surgical resection of the lesion, suggesting an inadequate…
- Conditions
- Cavernous Malformation, Cerebral, Cavernous Angioma, Cavernous Hemangioma, Cavernous Hemangioma of Brain
- Trial name
- CRESS (NCT04076449)
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- yuanli Zhao
Hearing Loss
Effect of Hearing Aid Labeling on Speech Understanding Measures
New and experienced hearing aid users will be fit with two hearing devices. One will be labeled as an OTC (Over-The-Counter) device, the other will be labeled as a Prescriptive (i.e. professionally fit) device.
- Trial name
- NCT05274178
- Testing
- Audeo P hearing aid labeled as "Prescriptive", Audeo P hearing aid labeled as "OTC"
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Postural Instability, Dentistry
Posture and Prevention: Evaluating an Exercise Program for Dental Students
Musculoskeletal disorders (MSDs) are a major public health concern, involving inflammatory and degenerative issues in muscles, tendons, joints, and nerves.
- Conditions
- Postural Instability, Dentistry, Musculoskeletal
- Trial name
- Evaluation (NCT06933485)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Post Operative Pain, Chronic Apical Periodontitis of Pulpal Origin
The Effect of Using Reciprocal Files Alone and With Different Files on Postoperative Pain
This study aims to investigate the effects of using the Wave One Gold file alone and in combination with different files on postoperative pain in patients with asymptomatic apical periodontitis.
- Trial name
- NCT06833515
- Testing
- one flare+wave one gold glider+wave one gold, wave one gold glider+wave one gold, wave one gold
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Harran University
Tibial Fractures, Fibula Fracture
Effect of Palmitoylethanolamide on Reducing Opioid Consumption for Below Knee Fracture Fixation
Palmitoylethanolamide (PEA), a non-psychoactive cannabis compound derived from peanuts, egg yolks, and soybeans, is an Endogenous FA Amide produced in the body as a biological response and a repair mechanism in chronic…
- Conditions
- Tibial Fractures, Fibula Fracture, Knee Fracture
- Trial name
- NCT05317676
- Testing
- Palmitoylethanolamide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Pain, Regulation, Self
Multisensory Integration and Pain Perception
Pain is a predominant disruption of well-being among humans. Feeling pain is a multimodal sensory experience where information is collected and processed from various senses such as sight and touch.
- Trial name
- NCT03471689
- Testing
- Mindfulness meditation, Positive reappraisal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hysterosalpingography-Related Pain
Pain Control During Hysterosalpingography: A Three-Arm Randomized Trial
Hysterosalpingography (HSG) is commonly performed during infertility evaluation and may cause pain during cervical manipulation, uterine distension, and contrast-medium injection.
- Trial name
- HSG-PAIN (NCT07792668)
- Testing
- Indomethacin 100Mg Suppository, Lidocaine %2 ampoule
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Coronary Angiography (CAG), Anxiety
Effect of VR Glasses and Stress Ball on Anxiety in Coronary Angiography Patients
This randomized controlled trial aimed to evaluate the effects of virtual reality (VR) glasses and the use of a stress ball on anxiety, pain, and satisfaction levels in patients undergoing coronary angiography.
- Conditions
- Coronary Angiography (CAG), Anxiety, Pain
- Trial name
- NCT07087990
- Testing
- Virtual Reality Glasses, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Pain
The Effect Of White Noise And Therapeutic Touch On Pain And Physiological Parameters In Premature Infants
Newborns hospitalized with some respiratory problems in the clinic are taken to noninvasive mechanical ventilation support and vascular access is required for some treatments to be applied to these newborns.
- Trial name
- NCT05395208
- Testing
- Therapeutic touch group accompanied by white noise
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Okan University
Emergence Delirium
Effects of Remifentanil Infusion on Emergence Delirium After Dental Surgery in Children
In this study, the investigators tried to show the effect of remifentanil on emergence delirium caused by sevoflurane used in general anesthesia.We planned a retrospective study. We formed two groups of 80 participants.
- Trial name
- NCT04300374
- Testing
- The Paediatric Anaesthesia Emergence Delirium scale assesment which was recorded postoperatively
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Voice Disorders, Muscle Tension Dysphonia
A Study to Evaluate Effects of Gargle Phonation in Voice
The purpose of this study is to assess subjects with muscle tension dysphonia for perceived effort and acoustic effects of gargle phonation compared to baseline and a sham water swallow.
- Conditions
- Voice Disorders, Muscle Tension Dysphonia, Speech Therapy
- Trial name
- NCT04766658
- Testing
- Gargle Phonation, Water swallow
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain
Study of Pain Processing in Experienced Yoga Practitioners
Background: Different people perceive the same pain differently. Mood, attention, stress, and personality affect how we feel pain.
- Trial name
- NCT02055235
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Amblyopia, Child
Early Vision Screening in High-risk Children
To evaluate the effect of early vision screening with automated photorefraction device in high risk children
- Trial name
- NCT02678468
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema
Cool vs Room-temperature Artificial Tears
Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort.
- Conditions
- Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema, Exudative Age-Related Macular Degeneration, Unspecified Eye, Cystoid Macular Edema
- Trial name
- NCT05832996
- Testing
- Refresh Plus Preservative-free Lubricant Eye Drops
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Apathy, Mild Cognitive Impairment
Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment
Apathy, a profound loss of initiative and motivation, is often seen in older Veterans with memory problems. Apathy leads to serious health problems, increases dependency, and caregiver burden.
- Conditions
- Apathy, Mild Cognitive Impairment, Transcranial Magnetic Stimulation, Loneliness
- Trial name
- TAMCI (NCT03590327)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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