Clinical trials: Neurological Condition
Fibromyalgia, Pain, Chronic
Psychobiological Mechanisms Underlying Chronic Pain
Pain is a powerful motivator of behavior and it is more than the perception of nociceptive input. It is a complex experience that comprises different components: sensory discriminative, emotional-motivational and cognitive…
- Conditions
- Fibromyalgia, Pain, Chronic, Chronic Pain, Widespread
- Trial name
- NCT04674670
- Testing
- Bromocriptine Mesylate Capsules, Amisulpride 400 MG
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- susanne becker
Sleep, Sleep Deprivation
Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes
This study aims to investigate the effects of 24-hour acute sleep deprivation on plasma Alzheimer's disease biomarkers and multi-omics in individuals with different APOE genotypes, to elucidate the potential role of acute sleep…
- Trial name
- NCT07085754
- Testing
- Sleep Deprivation
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuhui Qiu
Healthy
A Comparison of Two Different Methods to Reduce Intramusculer Injection Pain
When the literature is reviewed, there are few studies evaluating cold spray or ShotBlocker in reducing pain associated with IM injection.
- Trial name
- NCT04634942
- Testing
- Cryos REF 0971 Cold Spray, ShotBlocker BIONIX Press Firmly USA
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Inonu University
Muscle Wasting, Protein Intake
Effects of Ketones on Muscle Wasting During Caloric Restriction in Lean Females
Because of these anabolic properties of ketone bodies and the fact that ketone bodies prevent muscle protein breakdown for gluconeogenesis during energetic stress, ketone bodies can be a promising strategy to prevent or treat…
- Conditions
- Muscle Wasting, Protein Intake, Ketosis, Caloric Restriction
- Trial name
- NCT04744142
- Testing
- Ketone supplementation, Increased protein intake
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fear and Anxiety
The Effect of Virtual Reality on Pain, Anxiety, and Fear During Burn Dressing in Children
This research was conducted to determine the effect of VR on the pain, anxiety, and fear levels experienced by patients during burn dressing.
- Trial name
- NCT05032586
- Testing
- wearing virtual reality headsets
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain, Hyperalgesia
Reducing Nocebo Effects on Pressure Pain
Nocebo effects are known to adversely affect the experience of various physical symptoms, such as pain and itch. Nocebo effects can be induced by associative learning mechanisms of classical conditioning.
- Trial name
- NCT05284383
- Testing
- Closed-label nocebo conditioning, Closed-label counterconditioning, Open-label counterconditioning
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Leiden University
Pain, Postoperative
Effects of Lavender Oil on Postoperative Pain, Sleep Quality and Mood
This project will evaluate the integration of lavender essential oil in surgical patients during the perioperative and postoperative phase of care. The study will assess patients' pain, sleep quality, and mood.
- Trial name
- NCT03093454
- Testing
- Lavender Essential Oil
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Scott Hollenbeck, MD
Pain, Postoperative
Low Dose Caudal VS Dorsal Penile Nerve Block for Postoperative Analgesia After Circumcision
in order to eliminate fear and anxiety. Regional techniques are more effective than systemic opioids, non steroidal anti-inflammatory drugs, and acetaminophen for postoperative analgesia in circumcision, The most preferred…
- Trial name
- NCT05342259
- Testing
- Caudal nerve block /neuroaxial, Dorsal penile nerve block, Combined caudal and dorsal penile nerve block
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vasalgia, Headache
The Effect of Sphenopalatine Ganglion Block on Headache and Vasalgia
The purpose of this study is to evaluate the effect of sphenopalatine ganglion block (SPG block) on headache and veisalgia (hangover) the day after attending the metal festival Copenhell.
- Conditions
- Vasalgia, Headache, Hangover
- Trial name
- NCT07060586
- Testing
- Sphenopalatine Ganglion Block
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Osteoporosis, Sarcopenia
The Effect of 6 Months of Local Vibration Training in Institutionalized Elderly
This randomized controlled intervention study in institutionalized elderly investigates the effect of 6 months of local vibration therapy applied on the thigh and hip on muscle strength, muscle mass, bone density, and…
- Trial name
- NCT01499186
- Testing
- Local Vibration
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Virtual Reality
The Effect of Virtual Reality on Fear, Pain and Anxiety in Children Undergoing Circumcision
The aim of this study is to investigate the effect of virtual reality and cartoons and games on the anxiety, fear and post-procedural pain levels of children aged 7-12 years who will undergo circumcision.
- Trial name
- NCT06622369
- Testing
- Virtual Reality-Game group, Virtual Reality-Cartoon-video group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Post Operative Pain
Pre-incision Versus Lapaorscopic-assisted Transversus Abdominis Plane (TAP) and Rectus Sheath Block for Post-Cholecystectomy Pain
The goal of this clinical trial is to compare pre-incision vs laparoscopic assisted Transversus abdominis plane and rectus sheath block in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05856682
- Testing
- Laparoscopic-assisted TAP block(LATAP) and Rectus Sheath block
- Where
- Pakistan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Postural Imbalance, Gait, Unsteady
A Device for Screening of Fall Risk in the Elderly
This study evaluates the screening accuracy of a device (OAK) in assessing fall risk in the elderly, compared to the assessment provided by the Algorithm for Fall Risk Assessment of the Centers for Disease Control and Prevention…
- Trial name
- NCT02655796
- Testing
- OAK
- Where
- Italy
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
Muscle and Bone in Patients with Diabetes Mellitus and Neuropathy
The goal of this observational study is to evaluate muscle fiber type composition in people with type 2 diabetes mellitus (T2DM) with a common complication of T2DM: diabetic peripheral neuropathy (DNP), specifically diabetic…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy, Sarcopenia
- Trial name
- SVT-DNP (NCT06519942)
- Testing
- Blood sampling, Electromyoneurography (EMNG), Muscle biopsy
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Preterm Birth
Hammock Positioning's Influence on the Electromyographic Activity in the Flexor Muscles in Newborn Preterm
The individual who is born premature, in addition to a CNS still in accelerated training suffers early loss of intrauterine restraint, conditions that promote hypotonia characteristic of premature birth.
- Trial name
- NCT02621996
- Testing
- hammock, containment nest
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Cervical Pain
Instrument-assisted Soft Tissue Mobilization and Kinesiotape Application in Individuals With Chronic Neck Pain.
Chronic neck pain causes errors in joint position sense. There are studies in the literature suggesting that instrument-assisted soft tissue mobilization and Kinesiotape applications improve the joint position sense.
- Trial name
- NCT04765670
- Testing
- Instrument Assisted Soft Tissue Mobilization, Kinesiotape Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Movement Disorders, Muscle Tenderness
Verbal Cueing vs Constraint-Led Approach for Teaching the Kettlebell Swing
The purpose of this study is to determine which method is most effective for teaching the kettlebell swing: verbal cueing, physical constraints, or a combination of the two.
- Trial name
- NCT05560269
- Testing
- Verbal coaching vs. Constraint based coaching
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Post Operative Pain
Comparison Between Bupivacaine and Bupivacaine With Dexmedetomidine in Caudal Block for Post Operative Pain Control
The aim of this study is to compare the duration of analgesia, sedation, and intra and postoperative hemodynamics. This drug is recently available in Pakistan.
- Trial name
- NCT05919173
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution, Bupivacaine Hydrochloride 0.25% Injection plus Dexmedetomidine 1 microgram/kg body weight
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Tinnitus, Subjective
Advanced Neurofeedback for Tinnitus
This study investigates neurofeedback as a potential treatment for chronic tinnitus. Neurofeedback is a non-invasive method that aims to regulate brain activity and may help reduce tinnitus symptoms and the distress associated…
- Trial name
- ANTARES (NCT07830069)
- Testing
- Neurofeedback
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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