Clinical trials: Neurological Condition
Vaginal Packing Following Laparoscopic Sacrocolpopexy, Pelvic Organ Prolapse
Vaginal Packing After Laparoscopic Sacrocolpopexy
Vaginal packing is used routinely following vaginal reconstructive surgery, however, no recommendation regarding vaginal packing after laparoscopic sacrocolpopexy exists.
- Trial name
- NCT02943525
- Testing
- vaginal packing
- Where
- Czechia
- Volunteers
- 253 people
- Sponsor
- Charles University, Czech Republic
Neurological Diseases or Conditions, Stroke, Acute
COVID-19 Prevalence and Cognitive Deficits in Neurological Patients
The purpose is to investigate the COVID-19 prevalence, associated morbidity and long-term cognitive deficits in consecutive patients presenting with acute neurological symptoms
- Conditions
- Neurological Diseases or Conditions, Stroke, Acute, Seizure Disorder
- Trial name
- Neuro-Covid (NCT04377425)
- Testing
- COVID-19 swap test PCR
- Where
- 4 sites in Denmark
- Sponsor
- Aarhus University Hospital
Critical Illness, Sedation Complication
Sedation, ANalgesia and Delirium MANagement in Intensive Care Unit
Patients with acute severe health problems often need to be admitted to specialised hospital wards called Intensive Care Units (ICUs) where they can receive emergency treatment such as mechanical ventilation to support their…
- Conditions
- Critical Illness, Sedation Complication, Intensive Care Unit Delirium, Analgesia
- Trial name
- SAnDMAN (NCT05027217)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 3,421 people
- Sponsor
- University of Oxford
Pain, Chronic
Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients
This project examines the efficacy and feasibility of contingency management (CM), delivered using a novel, fully automated CM app (DynamiCare Rewards), to promote daily self-monitoring of pain symptom severity and related…
- Trial name
- ProMPT (NCT03962491)
- Testing
- Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Virginia Commonwealth University
Analgesia
Analgesic Protocol With Gabapentin Dexmedetomidine For Postoperative Pain Managment
Assessment of quality of post mastectomy analgesic protocol of Gabapentin and Dexmedetomedine in a placebo-controlled study
- Trial name
- NCT04976374
- Testing
- Dexmedetomidine and Gabapentin, Saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Low Back Pain, Facet Joint Pain
Ultrasound-Guided Thermocoagulation of Medial Nerve Branch in Lumbar Facet Joints Pain.
We propose here to evaluate the precision of lumbar thermocoagulation performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position.
- Conditions
- Low Back Pain, Facet Joint Pain, Facet Syndrome of Lumbar Spine, Chronic Low Back Pain
- Trial name
- NCT03564418
- Testing
- Ultrasound-Guided Thermocoagulation of Lumbar facet joints, Fluoroscopy-Guided Thermocoagulation of Lumbar facet joints
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Erasme University Hospital
Peripheral Arterial Occlusive Disease
Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream
The aim of this study is to assess, in patients scheduled for femoropopliteal bypass, the benefit of a double peripheral nerve block (femoral + sciatic) with levobupivacaine and clonidine in a single dose, performed before…
- Trial name
- BLOC-FEMPOP (NCT01785693)
- Testing
- levobupivacaine, clonidine
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Clermont-Ferrand
Low Back Pain, Sleep Disruption
Effects of Mattress Firmness on Pain in Patients With Chronic Low-Back Pain
The primary study objective is to determine whether mattress firmness affects pain in patients with chronic low-back pain. We hypothesize that mattresses that differ in their firmness and support should have a varying effect on…
- Trial name
- NCT01044121
- Testing
- Mattress Firmness
- Volunteers
- 40 people
- Sponsor
- Sleep To Live Institute
Surgical Wound, Post Operative Pain
Effect of Preemptive Etoricoxib and Dexamethasone on Wound Healing and Clinical Parameters After Third Molar Surgery
The goal of this clinical trial is to compare preemptive single-dose selective cyclooxygenase 2 (COX-2) inhibitor - etoricoxib and dexamethasone use in systemically healthy patients during the surgical extraction of impacted…
- Trial name
- NCT05791721
- Testing
- Etoricoxib 90 Mg Oral Tablet, Dexamethasone 4mg
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Aortic Aneurysm, Thoracoabdominal
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic aneurysms represent the most common and dangerous aortic diseases. Although conventional aortic repair techniques cure the disease, there is a high risk of paraplegia particularly in extensive thoracoabdominal aneurysms…
- Trial name
- PAPAartis (NCT03434314)
- Testing
- Minimally-Invasive Segmental Artery Coil-Embolization
- Where
- 29 sites in Austria, France and 7 more
- Volunteers
- 500 people
- Sponsor
- University of Leipzig
Tinnitus
Treatment Evaluation of Neuromodulation for Tinnitus - Stage A2
This is a four arm, patient subtyping and parameter optimisation study for a neuromodulation treatment for tinnitus.
- Trial name
- TENT-A2 (NCT03530306)
- Testing
- PS1-PS4, PS6-PS10, PS7-PS4
- Where
- Ireland
- Volunteers
- 191 people
- Sponsor
- Neuromod Devices Ltd.
Pain
Effectiveness of TU and MRT to Release Trigger Points to Increase RoM and Pain Relief in Upper TT
To find out the Effectiveness of Therapeutic Ultrasound and Myofascial Release Technique to Release Trigger Points to Increase Range of Motion and Pain Relief in Upper Trapezius Tightness
- Trial name
- NCT05854004
- Testing
- Therapeutic Ultrasound, Myofascial Release Technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Superior University
Post-surgical Pain, Pain, Acute
Utility of CYP2D6 Genotyping to Improve the Efficacy and Safety of Tramadol
Randomized clinical trial to evaluate the utility of CYP2D6 genotyping to improve the efficacy and safety of tramadol in the treatment of acute postoperative pain.
- Conditions
- Post-surgical Pain, Pain, Acute, Postoperative Pain
- Trial name
- Tradol-PriME (NCT05657704)
- Testing
- The patients in experimental group will be genotyped before surgery and treatment will be prescribed according to the CYP2D6 phenotype
- Where
- 8 sites in Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Failed Back Surgery Syndrome
Effect of Catheter Type on Efficacy of Percutaneous Caudal Adhesolysis
The approach toward FBSS involves conservative management that consists of physical therapy and medication which aims to optimize gait and posture and can improve muscle strength and physical function
- Trial name
- NCT06051149
- Testing
- caudal adhesolysis using RACZ Catheter, caudal adhesiolysis using NAVI Catheter
- Volunteers
- 78 people
- Sponsor
- Assiut University
Postpartum Disorder
The Effect of Back Massage Applied to Mothers in the Early Postpartum Period on Parameters
In the literature, there are separate studies on massage, comfort, anxiety, and physiological parameters for massage practice, but there are no studies that measure the physiological parameters of comfort, pain, anxiety, blood…
- Trial name
- NCT06200649
- Testing
- massage
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ordu University
Mitochondrial Diseases, Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
The KHENEREXT Study
This is an open-label, multi-centre study in subjects with a genetically confirmed mitochondrial deoxyribonucleic acid (DNA) transfer ribonucleic acid (tRNA)Leu(UUR) m.3243A>G mutation who completed study KH176-202.
- Conditions
- Mitochondrial Diseases, Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation, Maternally Inherited Diabetes and Deafness (MIDD), Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS)
- Trial name
- NCT04604548
- Testing
- Oral administration of 100 mg KH176 twice daily
- Where
- 4 sites in Denmark, Germany and 2 more
- Volunteers
- 11 people
- Sponsor
- Khondrion BV
Stroke
Telerehabilitation for Post-Stroke Hand Function
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke.
- Trial name
- NCT07792655
- Testing
- Technology-Supported Hand Training, Pamphlet-Supported Hand Activity
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Tissue Pain
Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
This study involves imaging the skin movements of surface tissue on the back. A clinician will perform assessment and intervention procedures manually, using manual and light movements of stretch and compression.
- Trial name
- OptMeasSkin (NCT06390085)
- Testing
- Soft tissue manipulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Temporomandibular Disorder, Myofascial Pain
CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Orofacial Pain, CBD
- Trial name
- NCT05562635
- Testing
- 5% polymer gel with CBD application, 10% polymer gel with CBD application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Sarcopenia
Ankle Assistance and Resistance in Older Adults
The goal of this research protocol is to improve mobility in older individuals through advances in wearable assistive devices by focusing on two specific aims.
- Trial name
- NCT06284525
- Testing
- Ankle resistance and biofeedback
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
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