Clinical trials: Neurological Condition
Piriformis Syndrome
Effects of MET and MFR on Piriformis Syndrome
The aim of this study is to comparatively evaluate the effects of two different manual therapy approaches, Muscle Energy Technique (MET) and Myofascial Release Technique (MFR), on pain threshold, muscle activation patterns, and…
- Trial name
- NCT07769203
- Testing
- Muscle Energy Technique, Myofascial Release Technique, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Igdir University
Stellate Ganglion Block
Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients
Delirium is a common complication in elderly intensive care unit (ICU) patients and is associated with poor clinical outcomes. Circadian rhythm disruption is considered an important contributing factor in delirium development.
- Trial name
- NCT07558642
- Testing
- stellate ganglion block with 0.5% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Antalya Training and Research Hospital
Labor Pain
Intravenous Remifentanil for Labor Analgesia
Labor analgesia is an essential health caring procedure for women. However, epidural analgesia cannot be performed on all subjects for different contraindications, such as lower platelet counter, back infection at the puncture…
- Trial name
- IRELAN (NCT00710086)
- Testing
- Hydromorphone, Remifentanil
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Dry Eye Syndromes, Meige Syndrome
Wumeiwan Jiawei Fang Use in Patients With Blepharospasm
To evaluate the efficacy and safety of Jing Fang Wu Mei Wan Jiawei Fang in the treatment of idiopathic blepharospasm using a clinical randomized controlled trial method.
- Conditions
- Dry Eye Syndromes, Meige Syndrome, Blepharospasm, Hyperactivity
- Trial name
- NCT05618470
- Testing
- Wumeiwan Jiawei Fang, botulinum toxin A
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China Academy of Chinese Medical Sciences
Knee Osteoarthritis
Knee Arthroplasty Pain Coping Skills Training (KASTPain): A Randomized Trial
Patients undergoing knee replacement surgery and who have high levels of pain catastrophizing are at risk for poor outcome. The clinical trial is designed to determine if a pain coping skills training intervention delivered by…
- Trial name
- KASTPain (NCT01620983)
- Testing
- Pain Coping Skills Training, Arthritis Education, Usual Care
- Where
- 5 sites in United States
- Volunteers
- 402 people
- Sponsor
- Virginia Commonwealth University
Postoperative Pain, Acute
Pulsed Shortwave Therapy for Postoperative Analgesia
Pulsed shortwave (radiofrequency) therapy is a possible method of pain control involving the application of electromagnetic energy (also termed pulsed electromagnetic fields).
- Trial name
- NCT05796583
- Testing
- Active Pulsed Shortwave Treatment
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Pain, Stress
Pain and Stress Assessment and ROP Screening
The study will measure the effects of eye exams on markers of stress in the urine. In addition, measurements will be taken to show the effects of stress on brain activity, O2 sats, and blood flow.
- Trial name
- NCT02415205
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Shoulder Pain
Neuroscience Education in Shoulder Pain: Clinical Trial
Objectives: The purpose of this study was to assess the efficacy of a pain neuroscience education programme applied to patients with shoulder pain.
- Trial name
- NCT06739694
- Testing
- PNE, Manual therapy
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Universidad de León
Tendonitis of the Shoulder, Elbow, or Knee
A Pilot Study on the Onset of Action of KTP, 20% in the Treatment of Acute Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee
Open-label study to be conducted at 2 US investigational sites in subjects who have acute tendonitis or bursitis of the shoulder, elbow, or knee.
- Trial name
- KTP (NCT00903994)
- Testing
- Ketoprofen Topical Patch 20%
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- APR Applied Pharma Research s.a.
Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders
Better Sleep in Psychiatric Care - ADHD Pilot Study
Comorbidities, including sleep problems, are common in adult Attention Deficit Hyperactivity Disorder (ADHD). Treatment of choice for insomnia is cognitive behavioral therapy (CBT-i), but evidence is lacking for CBT-i in patients…
- Conditions
- Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders, Sleep Wake Disorders
- Trial name
- BeSiP-ADHD (NCT03852966)
- Testing
- CBT-i/ADHD
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
Posterior Fossa Tumor
Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.
The goal of this clinical trial is to evaluate the effects of ultrasound-guided versus blind greater occipital nerve block (GONB), with or without Dexmedetomidine as an adjuvant, in pediatric patients undergoing posterior fossa…
- Trial name
- NCT07878156
- Testing
- Bupivacaine 0.25%, Dexmedetomidine 1mcg/kg, Blind greater occipital nerve block
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Chronic Pain, Hemophilia
Chronic Pain and Hemophilia
Hemophilia (A and B) are X-linked hereditary bleeding disorders whose severity depends on the level of coagulation factor (FVIII or FIX respectively). Bleeding is mainly from joints (hemarthrosis) and muscles (hematoma).
- Trial name
- HEMODOL (NCT05202951)
- Testing
- questionnaires
- Where
- 10 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anxiety, Depression
A Feasibility Study of a Guided Self-help Programme for Male Offenders Serving a Long-term Prison Sentence
Background: Prisoners have complex mental health needs, and there is a disproportionately higher incidence of mental health problems compared with the general population.
- Trial name
- NCT04746651
- Testing
- Guided Self Help
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Functional Neurological Disorder
Body Signal Integration Training: A Case Series
The goal of this clinical trial is to learn about an intervention package in individuals with Functional Neurological Disorder (FND).
- Trial name
- NCT05941702
- Testing
- Body Signal Integration Training
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Manchester
Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure
Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder Arthroscopy
During shoulder arthroscopy, fluid is pumped into the shoulder to help the surgeon see inside the joint. Some of this fluid can move into the tissues around the shoulder and neck and cause swelling.
- Conditions
- Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure, Neck Soft Tissue Edema
- Trial name
- NCT07852702
- Testing
- Elective Shoulder Arthroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Heat; Excess, Sleep Disorder
Effect of Sleep Debt on Neurophysiological Responses to Heat Exposure
Many people are required to work in stressful situations combining sleep debt and hot environmental conditions. If the effect of sleep debt on cognitive performance is proven, this effect could be increased, during heat exposure…
- Trial name
- ChaSPerf (NCT05181345)
- Testing
- Sleep recording (at home), Heat exposure, Normal sleep
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Low Back Pain
A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy
This is a multi-site feasibility trial of an embedded emergency department (ED) physical therapy care model for low back pain at two EDs in the Northwestern Medicine and University of Utah Health systems.
- Trial name
- FEED-PT (NCT07224945)
- Testing
- Embedded Emergency Department Physical Therapy, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Delirium
International Multicenter Study One Day Prevalence Observational Study for Delirium on ICU
An anonymous international multicenter - clinical survey, one-day observational study.
- Trial name
- IMPROVE-ICU (NCT01278524)
- Where
- Germany
- Volunteers
- 1,002 people
- Sponsor
- Claudia Spies
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