Clinical trials: Neurological Condition
Obstructive Sleep Apnea, Snoring
Childhood Adenotonsillectomy Study for Children With OSAS
The purpose of this research is to determine the effect of adenotonsillectomy surgery (removal of tonsils and adenoids) on obstructive sleep apnea syndrome (OSAS) in children.
- Trial name
- CHAT (NCT00560859)
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
- Where
- 6 sites in United States
- Volunteers
- 453 people
- Sponsor
- University of Pennsylvania
Sarcopenia, Sarcopenic Obesity
Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study
This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal).
- Conditions
- Sarcopenia, Sarcopenic Obesity, Frailty
- Trial name
- NCT05918159
- Testing
- Sarcopenia Assessment
- Where
- Portugal
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Universidade do Algarve
Pain, Postoperative
Comparative Assessment of Preoperative Versus Postoperative Submucosal Dexamethasone on Postoperative Complications Following Surgical Extraction of Mandibular Third Molar: Randomized Controlled Trial
The goal of this study is to compare the pain, edema and trismus of pre-operative versus post-operative submucosal dexamethasone in lower third molar surgical extraction done in healthy population.This is comparative study, will…
- Trial name
- NCT06160180
- Testing
- Dexamethasone
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Obesity, Compensated Cirrhosis
OPTIMIzing muScle Preservation in paTients wIth Cirrhosis
Patients with obesity and cirrhosis benefit from weight loss but are prone to sarcopenia (loss of muscle mass, strength, and function).
- Conditions
- Obesity, Compensated Cirrhosis, Sarcopenia
- Trial name
- OPTIMISTIC (NCT05367596)
- Testing
- Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Back Pain
Descriptive Analysis: STarT Back Screening Tool: Cross-sectional Survey & Chart Review
Keele STarT Back SCreening Tool (KSB) is a practical and validated bio-psychosocial questionnaire that stratifies lower back pain patients into 3 risk groups (low, medium, high), with suggested treatment guidelines for each…
- Trial name
- STarT Back (NCT03848988)
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Parker University
Amblyopia
NEIVATECH Virtual Reality-based System for Amblyopia
The NEIVATECH system has been designed to provide binocular vision training to 7-15 year old amblyopic children by discriminating Gabor patches presented with different contrast to each eye as a perceptual learning task.
- Trial name
- NEIVATECH (NCT04819386)
- Testing
- Active vision therapy sessions with the NEIVATECH Virtual Reality-based system
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Increase-Tech
Back Pain, Low, Back Pain
Quality Improvement re: Choosing Wisely Back Pain Measures
As
- Conditions
- Back Pain, Low, Back Pain, Back Pain Lower Back Chronic
- Trial name
- SCV LBP (NCT05413070)
- Testing
- Multimodal approach to QI for Low-Value Care
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Pain
The Effects of Vitamin B6 Supplementation on Pain Thresholds and Tolerance
This clinical trial aims to explore the effect of Vitamin B6 supplementation on pain thresholds and tolerance in healthy adults using thermal and electrical stimulation.
- Trial name
- NCT06415383
- Testing
- Vitamin B6 100 MG
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Reading
Chronic Pain, Pain, Chronic
Virtual Reality - A New Vision on Pain
The purpose of the project is to investigate if the use of virtual reality (VR) technology with pre-programmed proprietary software can provide better treatment for patients with long-term pain conditions.
- Conditions
- Chronic Pain, Pain, Chronic, Musculoskeletal Disorder, Musculoskeletal Pain
- Trial name
- VROP (NCT06045741)
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Sykehuset i Vestfold HF
Hearing Loss
Evaluation of a New mHealth Tympanometer
Children in rural and underserved communities experience a disproportionately high burden of infection-related hearing loss, which is often preventable with timely identification and follow-up care.
- Trial name
- NCT05666505
- Testing
- Prototype mHealth tympanometer, Standard of care commercial tympanometer
- Volunteers
- 39 people
- Sponsor
- University of Arkansas
Pain
Pregabalin and Remifentanil - Analgesia and Ventilation
In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.
- Trial name
- NCT01419405
- Testing
- Pregabalin, Remifentanil, sugar pill, saline infusion
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Trismus
Evolution of Mouth Opening After Mandibular Block
Trismus is an involuntary contracture of the masticatory muscles, blocking the opening of the jaw, first intermittent then permanent and irreducible.
- Trial name
- OBloc (NCT04961554)
- Testing
- loco-regional anesthesia
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Febrile Morbidity, Pain
Post-Operative Treatment With Ketorolac After Abdominal Myomectomy
The purpose of this study is to determine if ketorolac, given after abdominal myomectomy, will decrease the frequency of post-oerative fevers as well as improve post-operative pain management.
- Trial name
- NCT00845754
- Testing
- ketorolac, saline
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ascher-Walsh, Charles, M.D.
Gait Disorders, Neurologic, Stroke
Effectiveness of Multiple Robotic Gait-Devices for Improving Walking Ability in Subacute Stroke Patients
The purpose of this study is to know the effectiveness of different robotic devices for gait rehabilitation in stroke patients
- Conditions
- Gait Disorders, Neurologic, Stroke, Walking
- Trial name
- NCT05811494
- Testing
- Lexo, Lokomat, C-Mill
- Where
- 5 sites in Spain
- Sponsor
- Neuron, Spain
Chronic Shoulder Pain
Adduction and Infraspinatus Activity in Shoulder Pain
The goal of this randomized crossover trial is to determine whether different levels of shoulder adduction pressure during an external rotation exercise change shoulder muscle activity in adults with chronic shoulder pain and…
- Trial name
- ISADER (NCT07765056)
- Testing
- Shoulder External Rotation With 0 mmHg Adduction Pressure, Shoulder External Rotation With 5 mmHg Adduction Pressure, Shoulder External Rotation With 10 mmHg Adduction Pressure
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Chronic Low-back Pain, Self Efficacy
Pain Navigator Tool for Self-management in Back Pain: PATiENCe Trial
This study explores the experience of physiotherapists and patients using the Pain Navigator Tool during outpatient musculoskeletal consultations.
- Conditions
- Chronic Low-back Pain, Self Efficacy, Therapeutic Alliance, Communication
- Trial name
- PATiENCe (NCT04007822)
- Testing
- Pain Navigator Tool
- Where
- United Kingdom
- Sponsor
- Glasgow Caledonian University
Sleep Initiation and Maintenance Disorders
Combined Behavioral/Pharmacological Therapy for Insomnia
This study will determine how sleeping pills can be combined with nondrug treatments to maximize the benefits of therapy for insomnia.
- Trial name
- NCT00044629
- Testing
- Cognitive-Behavioral Therapy for Insomnia, zolpidem tartrate (Ambien)
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Duke University
Pregnancy, Unwanted
Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial
Despite global efforts to decrease discomfort during surgical abortion, pain remains a limiting factor in where and how procedures are performed.
- Trial name
- SALSA (NCT02447029)
- Testing
- vaginal 2% Xylocaine, standard lidocaine paracervical block
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Stanford University
Procedural Pain, Procedural Anxiety
Pain Elimination and Anxiety Control Through Experiential Virtual Reality
The goal of this clinical trial is to determine if active virtual reality is more effective than passive virtual reality and standard of care distraction in decreasing pain in children, from 8 to 21 years old, undergoing…
- Trial name
- NCT06504602
- Testing
- Active Virtual Reality, Passive Virtual Reality
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Stroke, Arm
Enhancing Recovery of Arm Movement in Stroke Patients
Many people who have had a stroke have problems recovering the use of their affected arm and these problems may persist for a long time.
- Conditions
- Stroke, Arm, Paresis
- Trial name
- ENHANCE (NCT02725853)
- Testing
- tDCS, personalized practice, non-personalized practice
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
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