Clinical trials: Neurological Condition
Chronic Pain, Osteo Arthritis Knee
rTMS for Relieving Chronic OA Pain
In this study the investigators aim to examine the effects of Transcranial Magnetic Stimulation (TMS) on hippocampal network connectivity and pain levels in individuals with pain due to knee osteoarthritis.
- Trial name
- NCT05097729
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Sponsor
- Northwestern University
Tourette Syndrome
Behavioral Therapy for Tourette Syndrome
This research is being done to determine whether a home-based behavioral therapy can be successfully used to treat tics in children with Tourette syndrome (TS).
- Trial name
- BTTS:HBTA (NCT03019731)
- Testing
- Therapist-directed Behavioral Therapy, Home-based DVD Therapy
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Johns Hopkins University
Low Back Pain, Recurrent
Effectiveness of a Pain Neuroscience Education Programme on Physical Activity in Patients With Chronic Low Back Pain
Proposing ways to effectively counter chronic low back pain through non-drug intervention is a major public health issue due to the prevalence and health costs of this condition.
- Trial name
- END-LC (NCT05840302)
- Testing
- Activity monitor, Questionnaire
- Where
- France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Montpellier
Arthritis, Rheumatoid, Pain
Chronic Pain in Rheumatoid Arthritis
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis.
- Trial name
- CPIRA-2 (NCT05038553)
- Testing
- No intervention
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Northwestern University
Spondylolysis
Effects of Low-intensity Pulsed Ultrasound on Pain and Functional Disability in Patients With Lumbar Spondylolysis
Low-intensity pulsed ultrasound (LIPUS) is effective in accelerating the healing of fractures, reduction in costs to the state, reduction in the numbers of those patients who progress from out-patient care to long term care who…
- Trial name
- NCT04814979
- Testing
- Low-intensity pulsed ultrasound (LIPUS), Routine physical therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Lahore
Stroke
Effects of tDCS on Quadriceps Strength After Stroke
Previous studies show that one session of tDCS allow to improve muscle strength in hemiparetic patients in anodal condition. We test a new electrods configuration : a anodale stimulation opposite to the cortical representation…
- Trial name
- tDCS(HE) (NCT02109796)
- Testing
- transcranial Direct current stimulation
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Pain
A Trial of SHR0410 Injection for the Treatment of Pain After Endoscopic Surgery of the Lower Abdominal
The study is being conducted to evaluate the efficacy and safety of SHR0410 injection for the treatment of pain after endoscopic surgery of the lower abdominal.
- Trial name
- NCT04852003
- Testing
- SHR0410 Injection, Morphine
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Headache
Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)
The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect.
- Trial name
- NCT04707586
- Testing
- Cold Application
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yasemin Kalkan Uğurlu
Hearing Loss
Internet Auditory Rehabilitation: Follow-up to Adult Hearing Screening
The purpose of this study is to see if a newly developed program called "I Manage my hearing loss" (iManage) will increase the number of individuals who visit an audiologist after failing a hearing screening.
- Trial name
- NCT04122183
- Testing
- iManage (my hearing loss)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Louisville
Chronic Pain
Effects of a Patient Driven Assessment Process With Complex Pain Patients
The objective of this study is to engage patients with chronic pain and other key stakeholders in an iterative process of pilot-testing a validated patient generated instrument, the Measure Yourself Medical Outcome Profile…
- Trial name
- PDAP (NCT02746354)
- Testing
- The MySupport tool
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kaiser Permanente
Postoperative Pain
Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects
Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now.
- Trial name
- NCT03058354
- Testing
- Propofol, general anaesthesia
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Brain Injury, Chronic
Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury
The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on long-term symptoms after brain injury.
- Trial name
- HYBOBI2 (NCT01986205)
- Testing
- Hyperbaric Oxygen, Minimal pressure air
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Lindell Weaver
Hepatectomy, Analgesia, Epidural
Bupivacaine Levels in Liver Resection Patients
Bupivacaine is a local anesthetic commonly used to manage postoperative pain. Liver resection patients typically have an epidural catheter placed preoperatively through which they receive a continuous infusion of bupivacaine and…
- Trial name
- NCT03145805
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Jessica Burjorjee, MD, FRCPC
Developmental Language Disorder
Syntactic Intervention for Cantonese-speaking Children With DLD
The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD).
- Trial name
- NCT06954194
- Testing
- Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Hereditary Spastic Paraplegia, Neurodegenerative Diseases
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders.
- Conditions
- Hereditary Spastic Paraplegia, Neurodegenerative Diseases, Pediatric Disorder, Spasticity, Muscle
- Trial name
- NCT05354622
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Ocular Conditions Resulting in Visual Impairment
Low Vision Patients' Preference for Colored Filters and Illumination for Near Reading Determined by the LuxIQ/2
The effect of tinted filters and illumination on the visual performance of patients with low vision (i.e., individuals with reduced vision that is uncorrectable with glasses, surgery or treatments) has been a topic of research…
- Trial name
- NCT03192722
- Testing
- Colored near reading glasses, Lighting as determined by LuxIQ/2 or OttLite Cobra
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Nova Southeastern University
Carotid Artery Disease, Stroke
Natural History of Carotid Atherosclerosis
A prospective study of 700 patients with coronary artery disease will undergo non invasive evaluation of their carotid arteries by ultrasound and microwave radiometry.
- Conditions
- Carotid Artery Disease, Stroke, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT01521351
- Where
- Greece
- Volunteers
- 700 people
- Sponsor
- National and Kapodistrian University of Athens
Breakthrough Pain, Pain Due to Certain Specified Procedures
Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment
This study aims to assess self reported procedural pain compared with background pain and evaluate pain intensity differences across six standard procedures.
- Conditions
- Breakthrough Pain, Pain Due to Certain Specified Procedures, Pain, Cancer
- Trial name
- NCT02437929
- Testing
- Mobilization, Positioning, Personal Hygiene Care
- Where
- Italy
- Volunteers
- 1,079 people
- Sponsor
- Antea Foundation
Postoperative Pain
Dexamethasone or Clonidine as Adjuncts to Ropivacaine for Caudal Analgesia on Analgesia Duration in Children
Comparing the duration of pain relief from caudal analgesia when adjuncts like dexamethasone, clonidine, or saline (salt water) are added to ropivacaine.
- Trial name
- NCT02773602
- Testing
- Dexamethasone, Clonidine, Normal Saline
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
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