Clinical trials: Neurological Development
Diet, Mediterranean, Pregnancy Related
Intervention Based on the Mediterranean Diet During Pregnancy and the First Two Years for the Improvement of Neurological Development
The main objective is to evaluate the effect of the Mediterranean diet during pregnancy and the first two years of the child\'s life on the child\'s neurodevelopment and behavior (externalizing and…
- Conditions
- Diet, Mediterranean, Pregnancy Related, Child Development, Infant Behaviour
- Trial name
- CONMED (NCT06614413)
- Testing
- Neurodevelopment and behaviour assesment 2 years old
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Intellectual Disability, Developmental Delay
Establishing the Clinical Utility of First StepDx PLUS and NextStepDx PLUS Study
The study uses a randomized controlled study design of pediatric neurologists and developmental pediatricians and front-line (primary care) pediatricians to determine if use of FirstStepDx PLUS and Next StepDx PLUS are associated…
- Trial name
- NCT02414438
- Testing
- FirstStepDX PLUS and NextStepDX PLUS Webinar, FirstStepDX PLUS and NextStepDX PLUS Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Opioid-Related Disorders, Substance-Related Disorders
Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000255
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Behavior Problem, Developmental Delay
Stamford Group Family Nurture Intervention
The purpose of this current study is to investigate the efficacy of a group model of Family Nurture Intervention in ameliorating behavioral problems in preschool-aged children.
- Conditions
- Behavior Problem, Developmental Delay, Emotional Disturbances, Family Conflict
- Trial name
- NCT03442439
- Testing
- Nutrition and Play Intervention, Family Nurture Intervention
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
Maternal Depression
Reducing Risk After an Adverse Pregnancy Outcome
This application to the Boston University Medical Center Institutional Review Board outlines a research plan devoted to identifying and managing maternal depression in Early Intervention (EI).
- Trial name
- NCT01182363
- Testing
- Project Solve Education
- Where
- 4 sites in United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Sleep Apnea, Sleep-Disordered Breathing
The Meaning of Dopaminergic Pathway in Sleep Breathing Disorders.
The participants in the study will be adult patients with suspected sleep-disordered breathing. A one-night polysomnography will be performed using the NOXA1 device (NOX Medical, Reykjavík, Iceland).
- Trial name
- NCT05890911
- Testing
- Polysomnography, Blood dopamine level measurement, Genetical test
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Chronic Pain
Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids
There are nearly one million veterans being treated with long-term opioid therapy (LTOT) for chronic pain. Numerous short and long-term harms associated with LTOT and mounting evidence suggest they have modest or no benefit.
- Trial name
- NCT04746833
- Testing
- SUMMIT, control
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Musculoskeletal Diseases, Work-Related Condition
Work-related MusculoSkeletal Disorders Questionnaire
Development and validation of a multi-factor and self-perceived risk assessment questionnaire, specifically referred to WMSDs-related pain and risk factors
- Trial name
- WMSD (NCT04192604)
- Testing
- WMSDsQ
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Prediction of High-risk Populations for Sarcopenia
Evaluation of a Sarcopenia Prediction Model and Development and Effectiveness of a Nursing Guidance Mobile App
We evaluated a model for the prediction of high-risk populations for sarcopenia in home settings, developed a sarcopenia nursing guidance mobile application, and assessed the effectiveness of this application in influencing…
- Trial name
- NCT05363033
- Testing
- sarcopenia nursing guidance mobile application was developed
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Memory Impairment, Age-related Cognitive Decline
Development of an Innovative Health Ingredient From Marine By-products for the Healthy Aging
This interventional, randomised, placebo-controlled and double-blind study aims to evaluate the effect of a dietary supplementation with a blue fish hydrolysate derived from marine by-products, containing peptides and n-3…
- Trial name
- BRAINBOOSTER (NCT04910399)
- Testing
- Blue fish hydrolysate
- Where
- 2 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Abyss Ingredients
Problem Behavior, Developmental Delay
Problem Behavior Assessment and Intervention in IDEA Part C Services
The purpose of this study is to evaluate the effect of function-based assessment and intervention to reduce problem behavior in children with developmental disability or delay in the context of IDEA Part C services.
- Conditions
- Problem Behavior, Developmental Delay, Developmental Disability
- Trial name
- NCT06771284
- Testing
- Function-based assessment and intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Visual Impairment
Development and Validation of an Automated Self-administered Visual Acuity System
Visual acuity tests, commonly conducted in clinics and used for health screenings, are becoming more in demand due to an aging population.
- Trial name
- AutoVA (NCT06540001)
- Testing
- Automated visual acuity
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Pain, Postoperative
Fentanyl Ultra Low Doses Effects on the Nociceptive Threshold
Exaggerated pain and hyperalgesia are major issues after surgery and can lead to chronic pain. Opioid are parts of pain sensitization processes but remain absolutely necessary in the intraoperative period.
- Trial name
- FENTANULD (NCT00454259)
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Metabolic Disease, Neurological and Mental Health Conditions
Singapore PREconception Study of Long-Term Maternal and Child Outcomes
We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes…
- Conditions
- Metabolic Disease, Neurological and Mental Health Conditions, Genetics Predisposition, Skin Condition
- Trial name
- S-PRESTO (NCT03531658)
- Where
- Singapore
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Developmental Delay, Preterm Children
Home-based Visual-motor Training Program on Kindergarteners
The study aims to investigate the feasibility and effectiveness of the traditional and computerized home-based visual-motor training programs on at-risk kindergarteners.
- Trial name
- NCT05605977
- Testing
- Traditional visual-motor training program, Computerized visual-motor training program
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Frailty Syndrome, Sarcopenia
Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults
This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in…
- Trial name
- FEXO-FRAIL (NCT07133581)
- Testing
- FEXO (Fun Exercise for Older Adults)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Developmental Delay
Comparing Two Protocols to Improve Reflex Integration and Functional Performance
The goal of this quantitative experimental study is to compare two occupational therapy interventions intended to improve functional skills.
- Trial name
- NCT05825248
- Testing
- Fine and gross motor treatment only, Reflex integration + fine and gross motor treatment
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Salus University