Clinical trials: Neurological Disease
Tinnitus, Subjective
The Study of Wuling Capsule in Treatment Chronic Tinnitus
To evaluate the effect of psychological/mental factors on the severity of subjective tinnitus, to observe the efficacy and safety of Wuling capsule in the treatment of chronic subjective tinnitus with emotional disorders, and to…
- Trial name
- NCT03674853
- Testing
- Wuling Capsule, Oryzanol
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Xijing Hospital
Bipolar Disorder, Mood Disorder
Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders
This study is designed to evaluate repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for depression. In rTMS, a rapidly changing magnetic field passes through your scalp and skull and generates a small…
- Conditions
- Bipolar Disorder, Mood Disorder, Unipolar Depression
- Trial name
- NCT00001545
- Testing
- Magstim Super Rapid Magnetic Stimulator, Cadwell MES-10
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Mental Health (NIMH)
Meralgia Paresthetica, Chronic Low-back Pain (cLBP)
Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain
This study is designed to compare the effectiveness of two physiotherapy techniques-Dry Needling and the Cyriax Technique-in people suffering from chronic low back pain (CLBP) that radiates to the outer thigh, a condition…
- Trial name
- NCT07089472
- Testing
- Dry Needling Therapy, Cyriax Technique
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Parkinson Disease, Nutritional and Metabolic Diseases
Influence of Glucose on Metabolism and Clinical Symptoms of Patients With Parkinson's Disease
Many patients with Parkinson's Disease (PD) report an increased consumption of fast-acting sugars. This tendency to consume sweet, high-sugar foods occurs in some patients even before the onset of cardinal motor symptoms.
- Conditions
- Parkinson Disease, Nutritional and Metabolic Diseases, Sugar Intake
- Trial name
- PaGlu (NCT05998772)
- Testing
- Oral Glucose Tolerance Test
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Schleswig-Holstein
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Sleep Deficiency and Stroke Outcome
Deficient sleep duration and sleep disturbances - such as insomnia, sleep disordered breathing (SDB) and restless legs syndrome (RLS)- are associated with hypertension and cardio-cerebrovascular morbidity and mortality.
- Conditions
- Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders, Insomnia, Restless Legs Syndrome
- Trial name
- NCT02559739
- Where
- 2 sites in Switzerland
- Volunteers
- 447 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Migraine
Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department
Collectively, evidence shows that a combination of medication and behavioral therapy is most effective for migraine care. The ED is a critical point of contact with the health care system for many migraine patients; in current…
- Trial name
- NCT02945839
- Testing
- Preventative Medication (PM), Enhanced Usual Care, PMR (progressive muscle relaxation therapy)
- Where
- United States
- Sponsor
- NYU Langone Health
Epilepsy
A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning (USF)
Increased computational power has made it possible to implement complex image recognition tasks and machine learning to be implemented in every day usage.
- Trial name
- NCT06705439
- Testing
- Nelli
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Neuro Event Labs Inc.
Parkinson Disease
A Study Evaluating Potential Screening Tools for Detecting Parkinson Disease
This study is designed as a prospective cohort study to test the strategy of combining two biomarkers of parkinsonism, olfaction and brain imaging with a radioactively labeled drug, [123I]β-CIT , in a population of first-degree…
- Trial name
- NCT00387075
- Testing
- [123I]β-CIT and SPECT imaging, [123I]β-CIT
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Alzheimer's Disease
Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease
Efficacy and safety study of ABT-288 in adults with mild-to-moderate Alzheimer's disease.
- Trial name
- NCT01018875
- Testing
- ABT-288, donepezil
- Where
- 21 sites in Russia, Ukraine
- Volunteers
- 242 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Elective Laparoscopic Cholecystectomy
The Effect of Respiratory Exercises on Abdominal Distension in Laparoscopic Cholecystectomy Patients
Laparoscopic cholecystectomy is the first-line treatment for symptomatic gallstones. Pneumoperitoneum is the process of expanding the abdominal cavity during the surgical procedure by introducing CO2 gas into the abdomen to widen…
- Trial name
- NCT06069557
- Testing
- Respiratory exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Pompe Disease
CPAP for Infantile Pompe Disease
Patients with infantile onset Pompe disease will be trained with continuous positive airway pressure to see if hypernasality can be improved.
- Trial name
- NCT02405624
- Testing
- continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Brain Diseases, Vertebral Artery Thrombosis
A PROSPECTIVE, MULTICENTER, SINGLE-ARM TRIAL FOR THE NEW SIZES OF BRIDGE STENTS FOR VERTEBRAL ARTERY STENOSIS: Bridge-MAX
Aprospective, multicentre, single-arm clinical trial in which approximately 36 subjects would be enrolled using the Bridge 4.5 mm and 5.0 mm stent in accordance with the inclusion and exclusion criteria in this protocol.
- Conditions
- Brain Diseases, Vertebral Artery Thrombosis, Vertebral Artery Stenosis
- Trial name
- NCT06186024
- Testing
- Bridge
- Where
- China
- Volunteers
- 36 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Colorectal Cancer
The Effect of Nutrition for the Colorectal Cancer Patients Receiving Chemotherapy-randomized Controlled Study
We use clinical trial to explore the effect of nutrition support in colorectal cancer patients receiving postoperative adjuvant chemotherapy.
- Trial name
- NCT04567459
- Testing
- Premium Amino Acids
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Bardet-Biedl Syndrome, POMC Deficiency
Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway
A trial to compare the weekly and daily formulations of setmelanotide in participants with genetic defects in the melanocortin-4 receptor pathway.
- Trial name
- NCT05194124
- Testing
- Setmelanotide 2 mg, Setmelanotide 2.5 mg, Setmelanotide 3 mg
- Where
- 7 sites in United States, Canada and 4 more
- Volunteers
- 19 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders
Evaluation of the Impact of Multiple Sclerosis and Its Treatments on Women Fertility
CONTEXT A desire for pregnancy is common in young patients with multiple sclerosis (MS). The impact of MS on women fertility is debated, and the impact of disease-modifying therapies (DMTs) on fertility is not well known.
- Conditions
- Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Fertility
- Trial name
- FERTIMUS (NCT07164924)
- Testing
- blood sample to analyse AMH level on the serum
- Where
- 27 sites in France, Martinique
- Volunteers
- 800 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Osteoarthristis
BFR Training and Knee Osteoarthritis
Knee osteoarthritis (KOA) is a chronic, progressive degenerative joint disease characterized by cartilage and bone degeneration, synovial inflammation, and structural changes.
- Trial name
- NCT07590323
- Testing
- Standard Treatment, Pain neuroscience education, Blood flow restriction training
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Hail
Aphasia, Stroke
Exploratory Evaluation of the Digital Therapeutic Device Zenicom for Subacute Stroke Aphasia
Clinical Trial Title A Multicenter, Single-Blind, Prospective, Randomized, Exploratory Clinical Trial to Evaluate the Safety and Efficacy of the Digital Therapeutic Device 'Zenicom' for Improving Aphasia in Patients with Subacute…
- Trial name
- NCT07397923
- Testing
- Zenicog, Conventional Speech Therapy
- Where
- 3 sites in South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Bundang Hospital
Encephalopathy, Developmental Delay and Behavioral Changes
RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
RCT for Intermittent versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
- Conditions
- Encephalopathy, Developmental Delay and Behavioral Changes, Cord Tumor Compression or Instability, Cord Tethering or Malformation
- Trial name
- NCT00515359
- Testing
- Intermittent Propofol Sedation, Continuous Propofol Sedation
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Corewell Health West
Chronic Pain, Musculoskeletal Pain
Equipping Patients Using Interventions for Pain and Depression
This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a…
- Conditions
- Chronic Pain, Musculoskeletal Pain, Depression, Health Equity
- Trial name
- EQUIPD (NCT06500780)
- Testing
- Coaching and Decision Aid
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Indiana University
Stress, Irritable Bowel Syndrome
Evaluating and Treating Potential Research Participants With Digestive Disorders
Background: Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these…
- Conditions
- Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain
- Trial name
- NCT01736280
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
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