Clinical trials: Neurological Disease
Pain, Chronic Pain
Decreasing Long-term Opioid Use in Cancer Survivors
This is a feasibility pilot trial assessing a behavioral intervention for chronic pain among disease-free cancer survivors to decrease long-term opioid dependence.
- Conditions
- Pain, Chronic Pain, Cancer Pain, Survivorship
- Trial name
- NCT05067556
- Testing
- Acceptance and Commitment Therapy for chronic pain (ACT-CP)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Hearing Loss
Validating the Hum Test
The sensitivity and specificity of the Hum Test is being investigated in it's ability to detect conductive hearing loss. The hum test is simply elicited by asking the subject to hum to him or herself for a few seconds at both a…
- Trial name
- NCT02740322
- Testing
- Hum Test, Weber Test, Audiogram
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Abdominal Pain, Abdominal Cramps
A Study on Intestinal Gas Symptoms to Evaluate the Effects of Gas Defense in Otherwise Healthy Adult
This is a randomized, double-blind, placebo-controlled trial to determine the safety and efficacy of Digestive Advantage™ Gas Defense formula, a probiotic dietary supplement.
- Conditions
- Abdominal Pain, Abdominal Cramps, Flatulence
- Trial name
- NCT00881322
- Testing
- BC-130 (Gas Defense)
- Where
- 2 sites in United States, Dominican Republic
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Miami Research Associates
Pressure Ulcer, Spinal Cord Injuries
Use of Adhesive Elastic Taping for the Therapy of Medium/Severe Pressure Ulcers in Spinal Cord Injured Patients
All patients with a significant deficiency of skin sensitivity and reduced mobility are potentially at risk of Pressure Ulcers (PUs), in particular the persons affected by Spinal Cord Injury (SCI), also due to their frequent…
- Trial name
- NCT03220451
- Testing
- Adhesive elastic taping
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Montecatone Rehabilitation Institute S.p.A.
Sleep Initiation and Maintenance Disorders
15-Day Repeated-Dose Study With SB-649868 And Its Interaction With CYP3A4 Isoenzyme In Healthy Male Subjects.
Subjects will be screened within 28 days, Simvastatin dose and single SB-649868 dose 10 and 7 days prior to repeat dosing respectively, 15 days SB-649868 repeat dosing with safety and cognition function tests.
- Trial name
- NCT00495729
- Testing
- SB-649868, Simvastatin
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Burnout, Insomnia
Improving the Mental Health and Well Being of Healthcare Providers Through the Transcendental Meditation Technique
The level of stress-related disorders experienced by Healthcare Providers (HCPs) has increased due to the recent COVID-19 Pandemic, impacting patient care and provider shortages.
- Conditions
- Burnout, Insomnia, Well Being
- Trial name
- NCT05239429
- Testing
- Transcendental Meditation Technique
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical and Cosmetic Research
Ischemic Stroke
Remote Ischemic Conditioning for Motor Recovery After Acute Ischemic Stroke
The most recent treatment for stroke rehabilitation is to combine physical training with other therapies to enhance or accelerate recovery.The hypothesis of this study is that remote ischemic conditioning (RIC) might have a…
- Trial name
- NCT05263531
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ji Xunming,MD,PhD
Gait Disorders, Neurologic, Parkinson Disease
Adaptive SCS for Treatment of Gait Disturbance in PD
Spinal cord stimulation (SCS) has been suggested by several research for treating PD gait disturbance. However, the side effects induced by body position change cannot fully addressed by conventional SCS.
- Trial name
- NCT04538131
- Testing
- sensor-driven position-adaptive SCS, conventional SCS
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Ruijin Hospital
Neurocognitive Disorders, Alzheimer Disease
Integration of Health Information Technology and Promotion of Personhood in Family-Centered Dementia Care
Alzheimer's disease and related dementias (ADRD) are leading causes of disability and often result in communication deficits of the person with dementia (PWD) that can complicate ADRD caregiving and clinical care.
- Conditions
- Neurocognitive Disorders, Alzheimer Disease, Caregiver
- Trial name
- NCT04571502
- Testing
- My PATI ( Person Assisted Touchscreen Interface)
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Florida International University
Ischemic Stroke
Predictors and Prognostic Factors on the Acute Ischemic Stroke
Through 5 years continuous observation of acute ischemic stroke patients in Neurology Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, clinical data about emergency treatment…
- Trial name
- NCT03122002
- Testing
- Drug Therapy, Routine Blood Test and Image Scan, Intravascular therapy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Tongji Hospital
Aging, Healthy Aging
Biological Effects in Consumers of Resveratrol-enriched Wine
The objective of this clinical trial is to compare the health conditions of the participating population before and after an intervention with Resveratrol enriched wine. The main questions it aims to answer are: 1.
- Conditions
- Aging, Healthy Aging, Sarcopenia, Obesity
- Trial name
- NCT05981053
- Testing
- Wine enriched with Resveratrol
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Alzheimer Disease
Efficacy and Safety of Curcumin Formulation in Alzheimer's Disease
Curcumin is shown to impact several different pathways of neuroprotection, however clinical trials have not shown positive results, due to the poor bioavailability of curcumin.
- Trial name
- NCT01001637
- Testing
- Curcumin Formulation
- Where
- India
- Volunteers
- 26 people
- Sponsor
- Jaslok Hospital and Research Centre
Stroke, Urinary Incontinence
Effect of Pelvic Floor Muscle Training in Stroke
Aim: To evaluate the long term effect of pelvic floor muscle training in women with urinary incontinence after ischemic stroke measured by quality of life paramters.
- Trial name
- NCT00258037
- Testing
- Pelvic Floor Muscle training
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Safety Issues, Effect of Drugs
The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells
To study the safety and effect of autologous umbilical cord blood stem cells for treatment brain injury
- Trial name
- NCT03696745
- Testing
- autologous umbilical cord blood stem cells, 0.9% Sodium-chloride
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Non-fluent Aphasia, Glioma
High-frequency nrTMS on the Contralateral Broca Mirror Area for Glioma Patients With Early Postoperative Aphasia
The goal of this randomized clinical controlled trial is to determine whether the application of high frequency neuronavigated repetitive transcranial magnetic stimulation (nrTMS) on the contralateral of Broca's area can…
- Trial name
- NCT05788445
- Testing
- nrTMS treatment
- Volunteers
- 48 people
- Sponsor
- Beijing Neurosurgical Institute
Polio
Pakistan Short Interval mOPV1 Compared With Standard Interval mOPV1 and bOPV 1,3
Globally, polio cases have decreased by over 99% since 1988. However, wild poliovirus cases continue in Pakistan. Conflict and lack of access to children due to on-going insecurity in tribal areas present special challenges in…
- Trial name
- SIAD (NCT01586572)
- Testing
- mOPV1, bOPV 1,3
- Where
- 2 sites in Pakistan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Genetic Disorder, Prader-Willi Syndrome
Retrospective Observational Study on Efficacy and Safety of Norditropin® in Children With Prader-Willi Syndrome
This study is conducted in Europe. The aim of this observational study is to collect data from children with Prader-Willi Syndrome, who have been treated off-label with Norditropin® for more than 12 months to seek approval for…
- Trial name
- NCT00705172
- Testing
- somatropin
- Where
- 3 sites in Denmark, Germany and 1 more
- Volunteers
- 41 people
- Sponsor
- Novo Nordisk A/S
Body Mass Index Quantitative Trait Locus 5 Disorder, Tangier Disease
Effect of High Protein Diet on Adiponectin and Inflammation Among Overweight and Obese Children
The investigators aimed to determine the effects of HP diet on adiponectin and inflammatory factors among overweight and obese children.
- Trial name
- NCT01886495
- Testing
- nutrition intervention
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Stroke
Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit…
- Trial name
- REACT-AVC (NCT07254195)
- Testing
- Telerehabilitation program using the MindMotion GO device
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
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