Clinical trials: Neurological Disease
Stroke, Ambulation Difficulty
Effect of Functional Electric Stimulation for Recovery of Dorsiflexion After Stroke
The purpose of this project is to investigate the effect of functional electrical stimulation (FES) for recovery of dorsiflexion after stroke.
- Conditions
- Stroke, Ambulation Difficulty, Hemiplegia
- Trial name
- NCT04945395
- Testing
- FES and Conventional training, AFO and Conventional training
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Danderyd Hospital
Delirium
Ramelteon Prevention of Delirium - RCT
Delirium is a common morbid condition in hospitalized adults. Treatment of delirium has been unsatisfactory and prevention is the preferred goal.
- Trial name
- NCT02564939
- Testing
- ramelteon
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Hartford Hospital
Stroke
Effects of Whole Body Vibration in People With Chronic Stroke
The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone health, physical fitness and neuromotor performance in patients with chronic stroke.
- Trial name
- NCT00937339
- Testing
- Whole body vibration therapy, Exercise on the vibration platform with the device turned off
- Where
- China
- Volunteers
- 82 people
- Sponsor
- The Hong Kong Polytechnic University
Cardiovascular Disease, Stroke
Heart Outcomes Prevention Evaluation-3
Heart disease and stroke are major causes of death and disability worldwide and are largely preventable. Cholesterol and blood pressure are major cardiovascular risk factors.
- Trial name
- HOPE-3 (NCT00468923)
- Testing
- Candesartan/HCT, Rosuvastatin
- Where
- Canada
- Volunteers
- 12,705 people, healthy volunteers welcome
- Sponsor
- Population Health Research Institute
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Gastric Cancer (GC), Stomach Neoplasms
TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial)
The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS) works to help people recover faster after laparoscopic surgery for stomach cancer.
- Trial name
- NCT07714980
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 13 sites in China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Spinal Muscular Atrophy (SMA)
A Study of the Safety and Preliminary Efficacy of NKG001 in Pediatric Patients With Type 1 or Type 2 Spinal Muscular Atrophy
This study is a single-center, open-label, single-arm, non-randomized, single-dose, dose-escalation investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, and preliminary efficacy of NKG001 Injection…
- Trial name
- NCT07617779
- Testing
- NKG001
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Nikegen Pharmaceutical (Hangzhou) Company Limited
Cerebral Palsy (CP)
Metacognitive Strategy Training Intervention for Transition-Age Youth With Cerebral Palsy
This exploratory randomized controlled trial will examine the feasibility and preliminary effects of a remote PREP intervention compared to an attention control for transition-age youth with cerebral palsy and their caregivers.
- Trial name
- NCT07424079
- Testing
- Pathways and Resources for Engagement and Participation, Attention Control Condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Missouri-Columbia
Schizophrenia, Mania
Aripiprazole Pharmacokinetics (PK) and Tolerability Study in Children and Adolescents
The purpose of this trial is to assess the safety, tolerability and pharmacokinetics of aripiprazole tablets following oral administration to children and adolescents.
- Trial name
- NCT00102479
- Testing
- Aripiprazole
- Volunteers
- 21 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Migraine Disorders
tDCS for the Treatment of Migraine
The aim of this study is to evaluate an optimized protocol of tDCS that normalize the lack of habituation and efficiency of inhibitory cortical circuits in migraine patients.
- Trial name
- NCT02562196
- Testing
- tdcs
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Delirium
Prophylactic Olanzapine Versus Placebo for Prevention of Postoperative Delirium After Joint Replacement Surgery
In this study we wanted to determine if perioperative administration of olanzapine prior to knee or hip replacement surgery in high risk patients would prevent the onset of postoperative delirium.
- Trial name
- NCT00699946
- Testing
- olanzapine
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Stroke, Sabacute Stroke
Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke
The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilitation, on motor recovery…
- Trial name
- BILAX (NCT06906588)
- Testing
- Experimental, Control
- Where
- 3 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Comparative Effects of Vestibular Rehabilitation With and Without Cervical JPS Training in Stroke Patients
Stroke is a neurological disorder that often causes long-term disability and affects an individual's quality of life. Patients suffering from stroke commonly experience difficulties with balance, gait, and sensory integration due…
- Trial name
- NCT07905703
- Testing
- vestibular rehabilitation With conventional PT, vestibular rehabilitation and cervical proprioception training with Conventional Pt
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Management and Technology Lahore
Intracranial Aneurysms
Canadian Study of the MicroVention Flow Re-Direction (FRED) Endoluminal Device Stent System in the Treatment of Intracranial Aneurysms
The study objective is to evaluate the safety and effectiveness of the MicroVention FRED System when used in the treatment of wide-necked intracranial aneurysms.
- Trial name
- CanFRED (NCT02309203)
- Testing
- FRED
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
COPD, Anxiety
Effect of Therapeutic Touch on Sleep Quality and Anxiety in Individuals With Chronic Obstructive Pulmonary Disease
Purpose: The purpose is to determine the effect of therapeutic touch on the sleep quality and anxiety of individuals with chronic obstructive pulmonary disease.
- Conditions
- COPD, Anxiety, Sleep
- Trial name
- NCT04842903
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Abant Izzet Baysal University
Migraine
Interest of Relaxation From Patients With Pain Due to Migraine
The purpose of this study is to determine whether relaxation (autogenic training of Schultz) is effective in treatment for migraine.
- Trial name
- MIGREL (NCT00904527)
- Testing
- relaxation (Schultz)
- Where
- 9 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Locally Advanced Rectal Cancer (LARC)
AI-Based Prediction of Pathological Response in Rectal Cancer Patients Receiving Total Neoadjuvant Therapy
This study aims to better understand how body composition, inflammation, and nutrition affect how rectal cancer responds to treatment.
- Trial name
- CINR-AI (NCT07049627)
- Testing
- Total Neoadjuvant Therapy (TNT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Ankara Etlik City Hospital
Cystic Fibrosis
Sleep in Patients With Cystic Fibrosis
The aim of the study is to identify the parameters that are associated with nocturnal hypoventilation in children and adults with cystic fibrosis.
- Trial name
- Sommeil (NCT00804661)
- Testing
- SENTEC device
- Where
- France
- Volunteers
- 76 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injuries
Use of Neural Functional Electrical Stimulation for the Recovery of Grasping Movements for Patient With Quadriplegia.
Functional electrical stimulation (FES) has been used for decades in rehabilitation centers. Having demonstrated efficacy for prevention of muscle atrophy following spinal cord injury (SCI), FES can also be considered for…
- Trial name
- NCT03721861
- Testing
- Intra-operative neural cuff stimulation
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Clinique Beau Soleil
Acute Sciatica, Lumbar Disc Herniation
Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation
Comparisons of surgical and non-operative treatment of patients with acute sciatica secondary to lumbar intervertebral disc herniation (AS/LDH) have shown no appreciable difference in outcome.
- Trial name
- NCT01552486
- Testing
- Chiropractic Spinal Manipulative Therapy, Usual Care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Vancouver General Hospital
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