Clinical trials: Neurological Diseases
Diabetes Mellitus, Diabetic Foot
Identification of Biomarkers for the Study of the Diabetic Foot and Evolution.
The European Working Group on Sarcopenia in the Elderly1 defines sarcopenia as a disorder of the progressive and generalized musculoskeletal system [1], which is associated with the increase and probability of adverse outcomes…
- Conditions
- Diabetes Mellitus, Diabetic Foot, Sarcopenia, Neuropathy, Diabetic
- Trial name
- SCFOOT (NCT05783700)
- Testing
- BIOIMPEDANCEMETRY
- Volunteers
- 300 people
- Sponsor
- Esther Soler
Preoperative Anxiety, Postoperative Delirium
The Effect of Preoperative Anxiety on Postoperative Delirium in Children
Investigation of the effect of preoperative anxiety on postoperative delirium in children who will undergo circumcision operation
- Trial name
- NCT04009200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Diskapi Training and Research Hospital
Chronic Pain, Post-traumatic Stress Disorder (PTSD)
Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans
The ANCHOR study is testing a novel, non-invasive brain stimulation program designed specifically for Veterans experiencing concurrent post-traumatic stress disorder (PTSD) and chronic pain.
- Trial name
- ANCHOR (NCT07192536)
- Testing
- Transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Legion Veterans Village Research Foundation
Gastroparesis
Needs Assessment Evaluating Quality of Life Issues for Gastroparesis Patients and Caregivers
The project will involve conducting a Needs Assessment for Gastroparesis patients and their caregivers with the goal of identifying quality of life issues associated with this disease.
- Trial name
- NCT01329211
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Florida
Benign Paroxysmal Positional Vertigo, BPPV
The Accuracy of Manual BPPV Diagnostics When Using VNG Goggles.
The aim is to investigate the accuracy of manual diagnostics of benign paroxysmal positional vertigo (BPPV) by comparing it to BPPV diagnostics in mechanical rotational chair (TRV chair).
- Conditions
- Benign Paroxysmal Positional Vertigo, BPPV, Vertigo, Vestibular Disorder
- Trial name
- NCT05846711
- Testing
- BPPV diagnostic, TRV chair, VNG goggles
- Where
- Denmark
- Volunteers
- 215 people
- Sponsor
- Aalborg University Hospital
Spinal Anesthesia, Intracranial Pressure Change
Effect of Spinal Needle Type on Optic Nerve Sheath Diameter
The optic nerve sheath is a continuation of the dura mater, extending along the subarachnoid space surrounding the optic nerve. Consequently, changes in intracranial pressure cause an augmentation or contraction in the diameter…
- Conditions
- Spinal Anesthesia, Intracranial Pressure Change, Optic Nerve Sheath Diameter, Orthopedic Surgery
- Trial name
- NCT06497634
- Testing
- 25 PP, 25 Q, 27 Q
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Bagcilar Training and Research Hospital
Neck Pain
Distance Learning and Neck Problems During Pandemic Period
For people who use computers a lot, Work-related musculoskeletal disorders of the neck are a common problem . It is generally agreed that the etiology of work-related neck disorders is multidimensional which is associated with…
- Trial name
- NCT04925999
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Misr University for Science and Technology
Low Vision, Retinitis Pigmentosa
Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision
Purpose: To validate a newly developed battery of performance-based tests of visual function to be presented using virtual reality.
- Conditions
- Low Vision, Retinitis Pigmentosa, Stargardt Disease 1, Stargardt Disease 3
- Trial name
- NCT04281732
- Testing
- Virtual Reality Headset based tests
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen's University, Belfast
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Liver Cirrhosis, Hepatocellular Carcinoma
Relevance of Sarcopenia in Advanced Liver Disease
Patients with established liver cirrhosis, or end-stage liver disease (ESLD), are at high risk of developing liver cancer (hepatic carcinoma; HCC), portal hypertension, and sarcopenia, all which lead to significant morbidity and…
- Conditions
- Liver Cirrhosis, Hepatocellular Carcinoma, Sarcopenia, Portal Hypertension
- Trial name
- ACCESS-ESLD (NCT05502198)
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Pain, Procedural, Pain, Postoperative
The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Removal of chest tubes after coronary artery bypass graft (CABG) surgery can cause severe pain and anxiety, which may negatively affect the recovery process.
- Conditions
- Pain, Procedural, Pain, Postoperative, Coronary Artery Bypass Surgery, Chest Tubes
- Trial name
- CABG (NCT06217263)
- Testing
- Vibration device, Vibration device&Cold application pack
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Fracture
Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department
The goal of this clinical trial is to learn if buprenorphine can treat pain in older adults who have broken bones. The main questions it aims to answer are: Is buprenorphine as effective as opioids to treat pain? Are there less…
- Trial name
- NCT07430345
- Testing
- Buprenorphine 0.15 MG, Hydromorphone 0.25 mg IV
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The Cooper Health System
Abdomen, Acute, Other Acute Pain
Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department
The purpose of this study is to compare the safety and effectiveness of intravenous low dose ketamine (LDK) to the industry standard of morphine (MOR) in regards to controlling acute pain in the emergency department.
- Conditions
- Abdomen, Acute, Other Acute Pain, Flank Pain, Back Pain
- Trial name
- NCT01538745
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brooke Army Medical Center
Traumatic Brain Injury
Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury
The global objective of this study is to establish the safety and investigate the potential treatment effect of an intravenous infusion of HB-adMSCs (Hope Biosciences adipose-derived mesenchymal stem cells) on brain structure…
- Trial name
- NCT05951777
- Testing
- Autologous HB-adMSCs, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Hope Biosciences LLC
Post Operative Pain, Postoperative Nausea and Vomiting
Postoperative Analgesia in Hip Arthroplasty
The goal of this clinical trial is to compare the analgesic effectiveness of two blocks in hip arthroplasty. The main question it aims to answer is -Which block is more efficient? Researchers will compare the suprainguinal fascia…
- Conditions
- Post Operative Pain, Postoperative Nausea and Vomiting, Hip Osteoarthritis
- Trial name
- NCT07153575
- Testing
- suprainguinal fascia iliaca block, Pericapsular nerve group (PENG) block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Breast Cancer, Postoperative Pain
Liposomal Bupivacaine in Implant Based Breast Reconstruction
Objectives: 1. To evaluate the effect of liposomal bupivacaine on postoperative pain levels. 2. To evaluate the effect of liposomal bupivacaine on postoperative opioid consumption and opioid related adverse events. 3.
- Trial name
- NCT02659501
- Testing
- Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Loma Linda University
Primary Progressive Aphasia, Repetitive Transcranical Magnetic Stimulation
rTMS Treatment of Primary Progressive Aphasia
Primary Progressive Aphasia (PPA) is a neurodegenerative disease in which language function is gradually and progressively impaired.
- Trial name
- NCT04431401
- Testing
- Magstim rTMS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Temporomandibular Joint Disorders, Dizziness
Investigation of the Aural Symptoms and Dizziness in Patients With Temporomandibular Joint Disorders
120 male and female patients aged between 18-65 years who apply to the outpatient clinic and diagnosed with TMD will be included in the study.
- Conditions
- Temporomandibular Joint Disorders, Dizziness, Tinnitus
- Trial name
- NCT05402228
- Testing
- temporomandbular joint disorders
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment
This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the subject, study partner, and site investigator, as well as…
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegenerative Disease, Hereditary
- Trial name
- NCT06177028
- Testing
- Lenalidomide 10 mg
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Hearing Loss
Littlears Auditory Questionnaire: Validation Study in CI Children
The LittlEARS Auditory Questionnaire is designed to assess the development of the auditory behavior in children during the first two (hearing) years.
- Trial name
- LittlEars (NCT00785707)
- Where
- 5 sites in United States
- Volunteers
- 31 people
- Sponsor
- Med-El Corporation
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