Clinical trials: Neurological Diseases
Neurological Complications, Mitral Valve Insufficiency
Magnetic Resonance Imaging for Cerebral Embolization During Minimal Invasive Mitral Valve Surgery
The purpose of this study is to prospectively evaluate major and minor neurologic events in patients undergoing right mini-thoracotomy mitral valve surgery and to compare different aortic clamping techniques; specifically, the…
- Trial name
- NCT02818166
- Testing
- Mitral valve surgery
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
Bipolar Disorder, Mania
Safety and Efficacy Study of Lithium in Bipolar Disorder
The purpose of this study is to determine whether Lithium is safe and effective in the treatment of Bipolar I Disorder subjects with symptoms of acute mania.
- Trial name
- NCT00422331
- Testing
- Lithium Carbonate Capsule
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- JDS Pharmaceuticals
Dementia Alzheimers
Surface EMG to Measure Paratonia in Dementia
Rationale: A prominent and degenerative motor symptom of dementia is paratonia that heavily affects quality of life. However, paratonia is poorly recognized and the diagnosis yet relies on subjective evaluation by caregivers.
- Trial name
- NCT05606445
- Testing
- Elbow movement
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Pain, Postoperative
Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy
Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation.
- Trial name
- NCT06186895
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Helwan University
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Musculoskeletal Pain, Musculoskeletal Injury
Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery
Work-related musculoskeletal pain and injury is a growing concern in surgery. Vaginal surgery has unique ergonomic risks, but no studies have addressed the potential for an exercise regimen to reduce physical strain by vaginal…
- Trial name
- SCORE (NCT06525701)
- Testing
- Execise Group, Control Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Loyola University
Labor Pain, Yoga
Nada Yoga Music Therapy for Pain and Anxiety in Labor
This study was designed as a randomized controlled trial. Based on the power analysis (Cohen's d = 0.80, α = 0.05, power = 80%), a total of 52 pregnant women were included, with 26 participants in the intervention group and 26 in…
- Conditions
- Labor Pain, Yoga, Music Therapy
- Trial name
- NCT07392112
- Testing
- Nada Yoga music therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sinop University
Epileptic Seizure, Creatine Kinase
Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected Seizure
Defining the origin of a seizure remains a difficult diagnosis. The presence of witness is not systematic, the clinical examination can be little contributory, and the delay recommended by the FSN is often surpassed for the…
- Conditions
- Epileptic Seizure, Creatine Kinase, Lactate, Epileptic Generalized Tonic-clonic Seizure
- Trial name
- NCT03163719
- Testing
- CK and Lactate dosages
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Ataxia, Cerebellar
tDCS Associated With Locomotor Training on Functional Mobility of Cerebellar Ataxia
Cerebellar ataxia is a neurologic symptom caused by a damage or a dysfunction in cerebellum and results in loss of coordination, balance and postural control.
- Trial name
- NCT03703830
- Testing
- Cerebellar transcranial direct current stimulation, Treadmill locomotor training, Cerebello-spinal direct current stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Hearing Loss
Clinical Trial Evaluating Outcomes of Self-Fit and Professionally Fit Hearing Aids
Approximately 48 million people in the United States have hearing loss or hearing difficulties in noisy environments. Whisper.ai Inc has previously brought to market a commercial hearing aid system that reduces background noise…
- Trial name
- NCT05527730
- Testing
- Comparison of PRO-FIT or SELF-FIT fitting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Whisper.ai
Charles Bonnet Syndrome
Neuroscience of Charles Bonnet Syndrome
Charles Bonnet Syndrome (CBS) is a condition in which people experience complex visual hallucinations, such as 'Acrobats balancing on bicycles' or 'Spiders crossing meals'.
- Trial name
- NCT04777630
- Testing
- None, neuroimaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Oxford
Cancer, Neurological Injury
Protein Top-up Acceptability Study for Patients With Increased Protein Needs
The aim of this prospective, single-arm intervention study is to evaluate the acceptability (compliance, gastrointestinal tolerance, and palatability) to a low calorie, low volume, ready to use, high protein liquid in patients…
- Conditions
- Cancer, Neurological Injury, Respiratory Disease, Stroke
- Trial name
- NCT04607330
- Testing
- High protein liquid
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Nutricia UK Ltd
Bipolar Disorder
A Study on the Safety and Efficacy of Topiramate in the Treatment of Patients With Bipolar I Disorder
The primary purpose of this study is to evaluate the safety and efficacy of topiramate compared with placebo in the treatment of acute manic or mixed episodes in patients with Bipolar I Disorder.
- Trial name
- NCT00035230
- Testing
- Topiramate
- Volunteers
- 338 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder
Mental And Speech Developmental Delay Autism Spectrum-Type Behavioral Disorder
FAMILY SYSTEM CITADEL 2060.METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085 Systemic work with brain neurons through training modules at the border of sleep in clinical, psychological and strategic logic.
- Conditions
- Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
- Trial name
- NCT07670000
- Testing
- Audio fairy tales
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Natalia Poluektova
Amputation, Traumatic, Pain, Phantom
Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)
In Ukraine, since the beginning of the full-scale war on February 24, 2022, a large number of individuals have lost a limb(s). Many of these amputees cannot access appropriate care in terms of pain management and rehabilitation.
- Conditions
- Amputation, Traumatic, Pain, Phantom, Pain, Acute, Pain, Chronic
- Trial name
- PAMELA (NCT06604507)
- Testing
- non-pharmacological app
- Where
- 5 sites in Ukraine
- Volunteers
- 200 people
- Sponsor
- Winfried Meißner
COVID-19, Olfactory Disorder
Efficacy of Gabapentin for Post-Covid-19 Olfactory Dysfunction
This study will investigate the efficacy of oral gabapentin in olfactory improvement following Covid-19- associated olfactory dysfunction. This is a randomized, double-blinded, placebo-controlled trial.
- Conditions
- COVID-19, Olfactory Disorder, Anosmia, Hyposmia
- Trial name
- GRACE (NCT05184192)
- Testing
- Gabapentin gelatin capsules 300mg
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Washington University School of Medicine
Behavior Disturbance, Muscle Hypotonia
Effect of Massage Therapy in a Multisensory Environment for Intellectual Disabilities
The aim of this study is to evaluate the effectiveness of multisensory environment (MSE) and/or massage therapy (MT) in residents with severe and profound intellectual disabilities (ID) who received massage therapy in MSE…
- Trial name
- MT-MSE (NCT02120820)
- Testing
- Multisensory environment (MSE), Massage therapy (MT), Control group
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The Hong Kong Polytechnic University
Low Back Pain, Spondylolisthesis
Slump Sitting X-ray of the Lumbar Spine Is Better Than Conventional Flexion View
This is a prospective, single-blinded, randomized-controlled study comparing a new method (slump-sitting) with the conventional method (forward erect bending) of performing lumbar spine flexion X-rays.
- Trial name
- NCT02547324
- Testing
- Slump sitting, Forward bending
- Volunteers
- 60 people
- Sponsor
- National University Hospital, Singapore
Spastic Paraplegia
Cognitive Disorders in Hereditary Spastic Paraplegia Type 4
Hereditary spastic paraplegia type 4 is the most frequent mutation of hereditary spastic paraplegias. It is commonly described as pure, with progressive weakness of the lower limbs, pyramidal syndrome and vesico-sphincter…
- Trial name
- SPG-TEP (NCT06260982)
- Testing
- 18-FDG-PET
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Systemic Sclerosis (SSc), Scleroderma
Investigation of Respiratory Muscle Sarcopenia in Patients With Systemic Sclerosis
The aim of this study was to investigate respiratory muscle sarcopenia in individuals with systemic sclerosis. The main question it aims to answer is: What is the prevalence of respiratory muscle sarcopenia in patients with…
- Trial name
- NCT06598982
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Selcuk University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.