Clinical trials: Neurological Diseases
Blepharospasm, Focal Dystonia
Brain Stimulation to Treat Blepharospasm or Meige Syndrome
This research study will examine whether magnetic or electrical stimulation of the brain can improve the involuntary closure of the eyelids in patients with blepharospasm or Meige syndrome; conditions that belong to a group of…
- Trial name
- NCT00411255
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cardiac Arrest
Non-invasive Neurological Evaluation During CPR
Cardiac arrest remains a leading cause of death, currently affecting >250,000 Europeans outside the hospital each year. Manual cardiopulmonary resuscitation (CPR) provides between 15 to 30 % of normal blood flow to the heart and…
- Trial name
- Neuro-E-CPR (NCT02684955)
- Testing
- Cerebral spectroscopy, Pupillometry
- Where
- 2 sites in France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Grenoble
Rotator Cuff Syndrome, Rotator Cuff Tears
Profiling the RCRSP Patient: a Pain Phenotype Classification Algorithm
The aim of this study is to collect a sum of different characteristics that have been mentioned previously in people presenting with RCRSP and by clustering them to create a phenotype system which may assist the individualisation…
- Conditions
- Rotator Cuff Syndrome, Rotator Cuff Tears, Rotator Cuff Tendinosis, Rotator Cuff Impingement
- Trial name
- NCT05817578
- Testing
- Quantitative Sensory Testing / Dynamometry / Goniometry
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Disorder of Consciousness
Transcranial Magnetic Stimulation in Patients With Disorders of Consciousness
Transcranial magnetic stimulation involves the use of alternating magnetic fields to stimulate neurons in the brain.To date, several studies have focused on the use of TMS in patients with impaired consciousness.However,its…
- Trial name
- NCT03385278
- Testing
- rTMS
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Coronary Disease, Coronary Artery Disease
SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters
The purpose of the SIROOP Registry is to retrospectively and prospectively collect baseline, clinical and procedural characteristics of patients who have undergone PCI and are treated with either currently available sirolimus or…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis, Coronary Arteriosclerosis
- Trial name
- SIROOP (NCT04988685)
- Testing
- Sirolimus Eluting Balloon
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Luzerner Kantonsspital
Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome
AKU Study - Acupuncture for Aromatase Inhibitor-Induced Musculoskeletal Syndrome
Third-generation aromatase inhibitors (AIs) represent a standard adjuvant endocrine treatment for postmenopausal and high-risk premenopausal women with hormone receptor-positive early breast cancer.
- Conditions
- Aromatase Inhibitor-Associated Musculoskeletal Syndrome, Arthralgia Syndrome, Early Breast Cancer (EBC)
- Trial name
- AKU (NCT07909785)
- Testing
- Manual Acupuncture
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Masaryk Memorial Cancer Institute
Abdomen, Acute, Myocardial Injury
MINS, AKI and Pulmonary Pathology in Patients Undergoing Acute Abdominal Surgery
Explorative study to investigate potential predictors of myocardial injury, acute kidney injury and pulmonary disorder after acute high-risk abdominal surgery.
- Conditions
- Abdomen, Acute, Myocardial Injury, Acute Kidney Injury, Pulmonary Disease
- Trial name
- NCT04681508
- Testing
- Chest CT without contrast enhancement and chest X-ray
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Nordsjaellands Hospital
Syringomyelia, Arnold Chiari Deformity
A Prospective Natural History Study of Patients With Syringomyelia
Background: Syringomyelia is a disorder in which a cyst (syrinx) forms within the spinal cord and causes spinal cord injury, with symptoms worsening over many years, including paralysis, loss of sensation, and chronic pain.
- Trial name
- NCT01150708
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sciatica
Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients
The main purpose of the study is to find the effects of Pilates exercises and neural mobilization techniques on pain, flexibility and quality of life in sciatica patients.
- Trial name
- NCT05959317
- Testing
- Pilates Exercises, Neural dynamic mobilization
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Elderly, Older Adults
The PAINFREE Initiative, a Stepped Wedge Cluster Randomized Trial
The PAINFREE (Improving PAIN control following FRactures; towards an Elder-friendly Emergency department) Initiative is a patient-centered multifaceted intervention which aims to improve pain management in patients 75 years and…
- Conditions
- Elderly, Older Adults, Bone Fracture, Emergency Department
- Trial name
- PAINFREE (NCT03082417)
- Testing
- Implementation
- Where
- Canada
- Volunteers
- 1,375 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain
Acupuncture in the Emergency Department
The investigators will study acupuncture in a pilot, randomized controlled trial (RCT) in the emergency department (ED) of a large, tertiary care hospital, Abbott Northwestern Hospital (ANW).
- Trial name
- NCT02888340
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Allina Health System
Sleep Disorder, Pregnancy Related
Vitamin D and Sleep Disorders in Pregnancy
Lack of sleep and poor sleep quality in pregnant women are associated with maternal depression and cognitive-sensual irregularities.
- Conditions
- Sleep Disorder, Pregnancy Related, Vitamin D Deficiency
- Trial name
- NCT04918368
- Testing
- Behavioral scales were used
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Delirium (POD)
Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery Patients
Postoperative delirium (POD) is a common complication in elderly patients undergoing cardiac surgery and is associated with prolonged hospitalization, increased morbidity, and poor recovery.
- Trial name
- NCT07768150
- Testing
- Dezocine, Normal Saline (NS)
- Where
- 2 sites in China
- Volunteers
- 640 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Ischemic Stroke
Speech and Language Therapy After Stroke
Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.
- Trial name
- NCT00713050
- Testing
- Imitate Therapy
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Chicago
Memory Disorders, Dementia
Maximizing Independence at Home (MIND at Home)
Funded by a unique private philanthropy and public coalition through THE ASSOCIATED: Jewish Community Federation of Baltimore, this project seeks to develop effective ways to deliver dementia care to older adults with memory…
- Trial name
- NCT01283750
- Testing
- care coordination
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Johns Hopkins University
Parkinson Disease, Other Neurological Disorders
Prevalence of Visual Dysfunction in Neurological Disorders
The objective is to determine the prevalence of visual dysfunction in People with Parkinson's Disease (PwP). The investigators will administer the: Visual Impairment in Parkinson's Disease Screen and Revised-Self-Report…
- Conditions
- Parkinson Disease, Other Neurological Disorders, Healthy
- Trial name
- NCT04836715
- Where
- 2 sites in United States
- Volunteers
- 92 people
- Sponsor
- University of Florida
Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms
Mindfulness-Based Education For Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovarian syndrome (PMOS), is the most common endocrinologic disorder to affect women. Despite this, the disease's pathophysiology remains unclear.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms, Stress, Quality of Life
- Trial name
- NCT07718217
- Testing
- Mindfulness-Based Polycystic Ovary Syndrome (PCOS) Education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Knee Osteoarthritis
Comparison of the Efficacy, Tolerability and Safety of actiTENS to Those of Level 2 Analgesic Treatments.
This is a phase 3, multicentre, prospective, single-blind on principal efficacy criterion, 2 parallel groups, randomized, controlled clinical study comparing efficacy and safety of actiTENS versus systemic level 2 analgesics…
- Trial name
- ArthroTENS (NCT03902340)
- Testing
- ActiTENS, Level 2 Analgesic Treatments
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Sublimed
Cardiovascular Diseases
Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina
The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery.
- Trial name
- NITRATE-OCT (NCT02529189)
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Queen Mary University of London
Neck Pain, Patient Education
Effects of Education and Exercise on Pain, Psychosocial Factors, and Upper Limb Function in Non-specific Neck Pain.
Pain neuroscience education is currently one of the techniques being explored in physiotherapy for pain management. The benefits of this technique are gradually becoming evident in various published studies.
- Conditions
- Neck Pain, Patient Education, Exercise Therapy, Fear
- Trial name
- PNE-EXNP (NCT06889389)
- Testing
- Education, Excercise
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Universidad Miguel Hernandez de Elche
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