Clinical trials: Neurological Diseases
Long COVID, Sars-CoV-2 Infection
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of…
- Conditions
- Long COVID, Sars-CoV-2 Infection, Coronavirus Infections, COVID-19
- Trial name
- REVERSE-LC (NCT06631287)
- Testing
- Baricitinib
- Where
- 17 sites in United States
- Volunteers
- 550 people
- Sponsor
- Wes Ely
Cancer, Chronic Obstructive Pulmonary Disease (COPD
Detection of Electrodermal Activity in Pain 2
The goal of this study is to investigate the association between self-reported pain and electrodermal activity and to create an algorithm that detects pain and provides timely alarms for rising pain levels in patients with…
- Conditions
- Cancer, Chronic Obstructive Pulmonary Disease (COPD, Pain
- Trial name
- DEEP 2 (NCT06677593)
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Developmental Delay, Disruptive Behavior
Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program
The Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program is a study funded by the National Institutes of Health to explore behavior and developmental problems among young children aging out…
- Trial name
- ACCESS (NCT03260816)
- Testing
- Internet-delivered Parent-Child Interaction Therapy (I-PCIT), Referrals as Usual (RAU)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Florida International University
Maximum Interincisal Opening
Effects of Exercise Therapy Adjuvant Device on Head and Neck Cancer Patients in the Treatment of Cancer Therapy Induced Trismus
Trismus is traditionally considered being a late effect of cancer therapy with functional deficits becoming clear in the first year after completing radiation therapy.
- Trial name
- NCT04740216
- Testing
- exercise therapy plus jaw device, exercise therapy
- Volunteers
- 130 people
- Sponsor
- Taipei Medical University
Patients of Laparoscopic Cholecystectomy
The Effect of Listening to Surah Al-Inshirah on Pain and Anxiety After Laparoscopic Cholecystectomy Surgery
In the postoperative period, good pain and anxiety management is required to minimize complications and ensure recovery. Patients should be evaluated with a holistic approach, taking into account factors such as physical and…
- Trial name
- NCT06042114
- Testing
- Surah Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Seher Tanrıverdi
Postherpetic Neuralgia
New Topical Treatment for Continued Pain After Shingles
Shingles is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chicken pox. Some people experience continued pain even after the shingles rash and blisters have healed; this pain is known as…
- Trial name
- NCT00566904
- Testing
- Epikeia coatings with aspirin, Epikeia coatings with lidocaine, Epikeia coatings alone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Biomedical Development Corporation
Coronary Artery Disease, Acute Myocardial Ischemia
Reduction of Ischemic Myocardium With Ranolazine-Treatment in Patients With Acute Myocardial Ischemia
The aim of the RIMINI-Trial is to examine the effect of Ranolazine on ischemic myocardium in acute myocardial ischemia. A pilot-trial by Venkatamaran et al.
- Trial name
- RIMINI-Pilot (NCT01797484)
- Testing
- Ranolazine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dyspnea, Chest Pain
Contactless Ultrasound Data Acquisition in Emergency Departments to Discriminate the Origin of Dyspnea and Chest Pain
PAnDA-One is a prospective, multicenter, interventional study (10 centers, France) aimed at developing and validating a diagnostic support algorithm based on the ADx-One medical device, which non-invasively acquires thoracic…
- Trial name
- PAnDA-One (NCT07653204)
- Testing
- All patients from both groups will be imaged with airborne ultrasound device
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Austral Diagnostics
Patellofemoral Disorder, Anterior Knee Pain Syndrome
Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Patellofemoral Pain Syndrome
This study compared the effects of patellar taping and electromyographic-biofeedback (EMG-BF) guided isometric quadriceps strengthening at different knee angles in patello-femoral pain syndrome (PFPS).
- Trial name
- NCT05055284
- Testing
- Electromyographic-biofeedback guided (EMG-BF) isometric quadriceps strengthening with patellar taping five days a week for six weeks.
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Majmaah University
General Surgery
The GUARDIAN Pilot Trial
The treatments will be: 1) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg, delayed resumption of chronic antihypertensive medications, and a target ward MAP ≥80 mmHg (tight pressure management)…
- Trial name
- GUARDIAN (NCT04789733)
- Testing
- Tight pressure management, Routine pressure management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Adhesive Capsulitis, Shoulder
Effectiveness of Focal Vibration in Shoulder Pathology
We hypothesize that focal vibration therapy will reduce pain, increase the mobilization of the glenohumeral joint, and will improve functionality in patients with adhesive capsulitis.
- Trial name
- FVinAC (NCT05214547)
- Testing
- Focal VibrationTherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bitlis Eren University
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Rotator Cuff-related Shoulder Pain, Shoulder Pain
Personalised Education Versus Usual Physiotherapy for Acute Rotator Cuff-Related Shoulder Pain
Rotator cuff-related shoulder pain (RCRSP) is one of the most common musculoskeletal disorders presenting in primary care. It is frequently associated with persistent pain, disability, healthcare utilisation and work absenteeism.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Pain, Shoulder Disability
- Trial name
- SHOULD-ER (NCT07859891)
- Testing
- Personalised, Multimodal Educational Intervention, Usual Physiotherapy Care
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Vaccination; Complications, Vaccine Adverse Reaction
Effectiveness of CARD for Improving School-Based Immunizations
Vaccination is estimated to have saved more lives in Canada than any other single intervention and is considered one of the most important advances in the prevention of disease.
- Conditions
- Vaccination; Complications, Vaccine Adverse Reaction, Fear
- Trial name
- NCT03966391
- Testing
- Multi-faceted knowledge translation intervention
- Where
- Canada
- Volunteers
- 8,839 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Analgesia, Breathing
Pain and Abdominal Breathing Exercises
Postoperative evaluation of patients who did and did not do preoperative abdominal breathing exercises.
- Trial name
- NCT05334160
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Tokat Gaziosmanpasa University
Childbirth, Pain
Mental Training and Childbirth
Labour pain is a challenge to the parturient woman. Pain relief methods during birth are limited and often associated with side effects.
- Trial name
- NCT00914082
- Testing
- Self hypnosis
- Where
- Denmark
- Volunteers
- 1,222 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoarthritis
Local Infiltration Analgesia or Intrathecal Morphine in Total Knee Arthroplasty
The purpose of this study is to determine whether local infiltration analgesia is more effective than intrathecal morphine in reducing postoperative pain in total knee arthroplasty.
- Trial name
- NCT00992082
- Testing
- ropivacaine, ketorolac and epinephrine, morphine
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Opioid-Related Disorders, Neuralgia
Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection
Using combination of opioid analgesics and analgesics with different mechanism of action the investigators can decrease the consumption of opioid analgesics and their side effects.
- Trial name
- NCT02616523
- Testing
- Dexmedetomidine, Lidocaine, Fentanyl
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Myofascial Pain Syndrome
Focused Shockwave Therapy for Neck and Shoulder Myofascial Pain
Myofascial pain syndrome of the neck and shoulder is a common condition characterized by persistent muscle pain, tenderness, stiffness, and limitations in daily activities.
- Trial name
- NCT07660523
- Testing
- Second-Generation Focused Extracorporeal Shockwave Therapy, Home-Based Neck Exercise Program
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
Cerebral Palsy
Functional Electrical Stimulation (FES) for Upper Extremity Hemiplegia in Children With Cerebral Palsy
The proposed pilot study seeks to explore the effectiveness of Functional Electrical Stimulation (FES) to improve upper limb function in children and youth (aged 6 to 18 years) with hemiplegic cerebral palsy, as measured by the…
- Trial name
- NCT03016923
- Testing
- FES Therapy
- Volunteers
- 3 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
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