Clinical trials: Neurological Diseases
Vision, Low
Project Magnify - A Comparison of Two Strategies to Improve Reading Ability
The purpose of Project Magnify is to determine which of the two current strategies (large print versus optical aids) for helping visually impaired students improve their reading abilities works better.
- Trial name
- NCT00366392
- Testing
- Optical Aids
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Taste Disorders, Orthodontic Appliance Complication
Evaluation of Taste Sensation Changes During Fixed Orthodontic Treatment
The aim of this study is to determine the changes in taste perception that may occur before and after the initiation of treatment in patients undergoing fixed orthodontic treatment.
- Conditions
- Taste Disorders, Orthodontic Appliance Complication, Malocclusion
- Trial name
- TASTEFIXED (NCT06989736)
- Testing
- Taste Test
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Biruni University
Gingival Recession, Mucogingival Surgery
Effects of Low-Level Laser Therapy and Hyaluronic Acid After Free Gingival Graft
The goal of this randomized clinical trial was to learn whether low-level laser therapy or hyaluronic acid application improves healing after free gingival graft surgery in adults with insufficient keratinized gingival tissue in…
- Trial name
- NCT07751211
- Testing
- Topical Hyaluronic Acid Gel, Low-Level Laser Therapy, Free Gingival Graft Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Altinbas University
Thoracotomy, Thoracoscopy
Physiopathologic Study of Induced by Thoracotomy / Thoracoscopy Neuropathy Mechanism
Pulmonary surgery, performed routinely by thoracotomy or thoracoscopy, can cause significant and frequent chronic postoperative pain, most often neuropathic.
- Trial name
- NITT (NCT05307471)
- Testing
- Thoracotomy/scopy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Clermont-Ferrand
Back Pain
BACk Pain in Elders in Norway (BACE-N)
An international Consortium (BACk pain in Elders: BACE) was established in 2008 in order to create standardised methodology for large cohort studies and share data on the burden of back pain in older people.
- Trial name
- BACE-N (NCT04261309)
- Testing
- Usual care
- Where
- Norway
- Volunteers
- 452 people
- Sponsor
- Oslo Metropolitan University
Hearing Loss, Sensorineural, Cognitive Impairment
Administration Method of Cognitive Screening in Older Individuals With Hearing Loss
The objectives of the current project aim to determine whether a more controlled amplification method or a visual administration has an effect on hearing impaired older individuals' cognitive test scores.
- Trial name
- NCT03402932
- Testing
- Auditory amplified, Visual, Auditory unamplified
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Thoracic Aneurysm
Effectiveness of Acetazolamide in Reducing Paralysis of the Leg in Patients Undergoing Aortic Aneurysm Surgery Surgery
The aorta is a large vessel that carries blood away from the heart. Sometimes it becomes dilated (swells) and this is known as 'aneurysm'. It may cause either dissection (splitting of the wall) or rupture (bursting).
- Trial name
- AZATAAR (NCT01889498)
- Testing
- Acetazolamide
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth
Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care
The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the…
- Conditions
- Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth, Cerebral Palsy, Neurological Disorder
- Trial name
- NCT06643598
- Testing
- Abecedarian Approach
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Wisconsin, Madison
Hyperalgesia
Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol
Opioid Induced Hyperalgesia (OIH) is an entity than has been demonstrated in healthy volunteers and in animal models. Is defined as an increase in the perception to painful stimuli, increasing the opioid requirements and…
- Trial name
- NCT02934763
- Testing
- Propranolol, Saline
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Muscle Weakness
Maximal Strength Training in Patients Undergoing Total Hip Arthroplasty
Conventional rehabilitation after total hip arthroplasty (THA) does not seem to restore muscular strength or walking speed. Three-5 years after surgery patients are still not fully rehabilitated.
- Trial name
- NCT02498093
- Testing
- Maximal strength training, conventional rehabilitation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Visual Perceptual Weakness (Disorder), Cerebral Visual Impairment
iVision - Development of a Game-based Therapy for Children With Cerebral Visual Impairment
The objective of the present study is to develop a therapeutic, adaptive, and enjoyable game that will be used by children with CVI between the mental age of 3 and 12 years.
- Trial name
- iVision (NCT04051983)
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Analgesia, Surgery
Transversus Abdominis Plane Block Compared to Local Anesthetic Wound Infiltration in Gynecologic Oncology Surgery
This study is being done to see if preoperative transversus abdominis plane (TAP) analgesia will provide similar postoperative pain control, hospital length of stay, and postoperative outcomes compared to surgeon-initiated wound…
- Trial name
- NCT06213454
- Testing
- TAP Anesthesia, Surgeon-Initiated Local Anesthetic
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Wisconsin, Madison
Migraine
Validation of a Questionnaire for Allodynia in Migraine.
Migraine is very frequent (15% of the general population). During attacks, many subjects with migraine have allodynia (pain induced by normally non-painful stimuli), photophobia (hypersensitivity to light), phonophobia…
- Trial name
- Q-MIGAL (NCT04580641)
- Testing
- Questionnaire
- Where
- 14 sites in France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Coronary Artery Disease
Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Binodenoson (an experimental drug) and adenosine (an FDA-approved drug that is currently used by doctors) are used to increase blood flow to the heart just like when a person exercises on a treadmill.
- Trial name
- VISION-302 (NCT00944294)
- Testing
- binodenoson, adenosine
- Volunteers
- 419 people
- Sponsor
- Pfizer
Spinal Cord Injuries
Immediate Effects of Stepping Training Using External Feedback in Spinal Cord Injury Patients
Does stepping training with or without external feedback change functional ability of ambulatory patients with iSCI immediately after training? Are there significant differences between the immediate effects of stepping training…
- Trial name
- NCT03875066
- Testing
- Stepping training without feedback, Stepping training with feedback
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Khon Kaen University
Fragile X Syndrome (FXS)
Novel Clinical Target in Fragile X Syndrome
Fragile X syndrome (FXS) is the most common genetic cause of autism spectrum disorder (ASD). The investigators wish to examine brain distribution of sigma-1 receptors in young adult males with FXS using 18F-FTC-146 PET.
- Trial name
- NCT04314856
- Testing
- 18F-FTC-146
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Guido A. Davidzon, MD, SM
Neuropathic Pain, Complex Regional Pain Syndromes (CRPS)
Sub-threshold DRG Stimulation vs Sham in Established Responders
The goal of this clinical trial is to learn if sub-threshold dorsal root ganglion (DRG) stimulation provides pain relief beyond placebo in adults with chronic neuropathic pain who already have an implanted DRG stimulator.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndromes (CRPS), Causalgia, Chronic Pain
- Trial name
- DRG-SHAM (NCT07170722)
- Testing
- Subtreshhold DRG-S
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Lumbar Radiculopathy
Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy.
Lumber radiculopathy, also known as sciatica, is a condition that causes pain in the lower back and legs due to irritation or compression of the spinal nerves. group between 20 and 50 years old.
- Trial name
- NCT06339931
- Testing
- SMWLM combined Spinal traction with belt, SMWLM combined spinal traction without belt
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Shoulder Pain
Non-interventional Study Evaluating the Management of Pain Using a Technique Developed and Commonly Used by the Center, in Patients Who Underwent Arthroscopic Surgery of the Shoulder in the Outpatient Setting.
Shoulder surgery is performed usually under interscalene block considered as a gold standard. This anesthesia is well suited for hospitalized patients but not for outpatients.
- Trial name
- BSS-CHIR (NCT04189731)
- Where
- France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Limoges
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