Clinical trials: Neurological Diseases
Child Behavior, Pain
The Effect of Therapeutic Play on Children's Pain and Fear and Parents and Students' Satisfaction Levels
This study aims to determine the effects of playing with therapeutic toys made by nursing students on children's fear and pain levels towards treatment and the satisfaction levels of student nurses and parents.
- Conditions
- Child Behavior, Pain, Anxiety, Anxiety and Fear
- Trial name
- NCT06593002
- Testing
- Therapeutic play
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selcuk University
Cardiac Arrest
Seizure Detection Using SEDline During Therapeutic Hypothermia in Cardiac Arrest Victims
Current guidelines recommend the use of sedatives and neuromuscular blocking agents to avoid shivering during therapeutic hypothermia in cardiac arrest victims.
- Trial name
- NCT01946802
- Testing
- Frontal 4 channel EEG
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Gil Joon Suh
Diabetic Peripheral Neuropathy
Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy.
The aim of this study is to determine comparative effects of balance and resisted training on pain and balance in patients with daibetic peripheral neuropathy.
- Trial name
- NCT06303453
- Testing
- Balance exercises, Resisted exercises
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Low Back Pain, Spondylolisthesis
Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device
Lumbar spinal fusion is commonly performed as a "last resort" in patients with chronic low back pain caused by degenerative changes and instability of the spine.
- Conditions
- Low Back Pain, Spondylolisthesis, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT00095095
- Testing
- Lumbar Interbody Fusion
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 102 people
- Sponsor
- Medtronic Spinal and Biologics
Musculoskeletal Pain, Neck Pain
Pain Modulatory Profiles in Massage for Individuals With Neck Pain
One in ten adults experience widespread pain. Neck pain, for example, is a prevalent condition with a high rate of recurrence that affects between 10.4% and 21.3% of the population annually.
- Trial name
- NCT03534739
- Testing
- Pain Inducing Massage, Light Touch Massage, Coldpressor
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Florida
Analgesia
Ultrasound Guided Thoracic ESPB for Post Mastectomy Pain Control, Comparing 2 Dosing Regimens of Lidocaine With Different Drug Volumes
The investigators compare 2 different drug regimens using 2 different volumes of lidocaine with the same drug content (i.e. different concentrations) as regards efficacy of post operative analgesia following mastectomy surgery
- Trial name
- NCT05514977
- Testing
- Erector spine plane block
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
Emergence Delirium
Namsos Anaesthesia Children Outcome Study
Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital.
- Trial name
- NACOS (NCT04292457)
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in Norway
- Volunteers
- 761 people
- Sponsor
- Helse Nord-Trøndelag HF
CerebroSpinal Fluid (CSF) Leak
NoSeal Trial: Comparing Sealants Versus No Sealant for Preventing CSF Leak After Endonasal Skull Base Surgery
Postoperative cerebrospinal fluid (CSF) leak is a significant complication of endoscopic endonasal approaches (EEA) to the skull base.
- Trial name
- NoSeal (NCT07216157)
- Testing
- Standard multilayer closure without sealant, Fibrin sealant application, Synthetic polyethylene glycol-based sealant
- Where
- Poland
- Volunteers
- 225 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Neck Pain, Shoulder Pain
Superficial Cervical Plexus Block for Neck and Shoulder Pain
Myofascial pain is an important cause of neck pain or neck and shoulder pain. Neck shoulder pain is a common socioeconomic problem that negatively affects the quality of life.
- Trial name
- NCT03210181
- Testing
- Superficial cervical plexus block
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Occupational Diseases, Muscle Pain
Musculoskeletal Problems and Strategies Developed by Physiotherapists to Cope With Them
The aim of this study is to investigate whether there is a difference in areas such as occupational musculoskeletal injuries and strategies developed by physiotherapists working in different fields, burnout and occupational…
- Trial name
- NCT06006481
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Herpes Zoster, Neuralgia
Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is to assess the efficacy, safety and tolerability of NGX 4010 applied for 60 minutes for the treatment of PHN.
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00068081
- Testing
- Capsaicin Dermal Patch
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- NeurogesX
Alzheimer's Disease, Dementia
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease
Donepezil hydrochloride (Aricept) has been approved to treat symptoms associated with mild to moderate Alzheimer's disease (AD).
- Trial name
- NCT00096473
- Testing
- Donepezil hydrochloride
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 229 people
- Sponsor
- Eisai Inc.
Kidney Cancer, Melanoma (Skin)
Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases
RATIONALE: Cryoablation kills cancer cells by freezing them. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells.
- Conditions
- Kidney Cancer, Melanoma (Skin), Metastatic Cancer, Pain
- Trial name
- NCT00540969
- Testing
- cryosurgery, radiation therapy
- Where
- 7 sites in United States
- Volunteers
- 3 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Visual Analogue Pain Scale, Pain Measurement
Efficacy of Radiofrequency Nucleoplasty and Targeted Disc Decompression in Lumbar Radiculopathy
The aim of this study is to compare early and long term efficacy of lumbar radiofrequency nucleoplasty and targeted disc decompression in patients with lumbar radiculopathy who failed previous conventional therapy.
- Trial name
- RFNaTDD (NCT02025283)
- Testing
- Group Decompression or Group Nucleoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Ankara University
Subacromial Pain Syndrome, Rotator Cuff Related Shoulder Pain
Predictive Model for PENS Response in Subacromial Pain Syndrome
Subacromial pain syndrome (SPS) is one of the most common causes of shoulder pain, leading to significant disability and socioeconomic burden.
- Trial name
- NCT07063641
- Testing
- Percutaneous Electrical Nerve Stimulation (PENS)
- Volunteers
- 269 people
- Sponsor
- Néstor Requejo Salinas
Autoimmune Disease, Neurologic Autoimmune Disease
Autologous Stem Cell Transplant for Neurologic Autoimmune Diseases
This phase II trial studies the side effects and how well carmustine, etoposide, cytarabine and melphalan together with antithymocyte globulin before a stem cell transplant works in treating patients with autoimmune neurologic…
- Conditions
- Autoimmune Disease, Neurologic Autoimmune Disease, Autologous Transplant Autoimmune, Multiple Sclerosis Transplant
- Trial name
- NCT00716066
- Testing
- Anti-Thymocyte Globulin, Autologous Hematopoietic Stem Cell Transplantation, Carmustine
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Fred Hutchinson Cancer Center
End Stage Renal Disease, Olfactory Disorders
Helping Olfaction and Nutrition On Renal Replacement
This clinical trial examines whether nasal theophylline administration can improve olfaction and nutrition in hemodialysis patients.
- Trial name
- HONORR (NCT02479451)
- Testing
- Theophylline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Opioid Use Disorder, Opioid Dependence
Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients
The purpose of this study is to examine whether buprenorphine can be at least as effective as other opioid medications in relieving chronic pain in patients who suffer from dependence on their opioid medications, while patients…
- Conditions
- Opioid Use Disorder, Opioid Dependence, Chronic Pain
- Trial name
- NCT01841931
- Testing
- Buprenorphine/Naloxone
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Theresa Jacob, PhD, MPH
Dyslexia, Speech Therapy
Comparative Impact of Protocolized Management, Intensive Rehabilitation Versus Long-term Classic Rehabilitation of Dyslexic Children.
Dyslexia is characterized by difficulties with accurate and/or fluent word recognition and by poor spelling and decoding abilities. In France, dyslexia is a public health disorder.
- Conditions
- Dyslexia, Speech Therapy, Children, Only
- Trial name
- INTENS-DYS (NCT05383937)
- Testing
- Speech Therapy INTENS-DYS
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hunter Syndrome, Mucopolysaccharidosis II
Biomarkers for Hunter Syndrome
International, multicenter, observational, longitudinal study to establish Hunter Syndrom biomarker/s and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s
- Conditions
- Hunter Syndrome, Mucopolysaccharidosis II, Hunter's Syndrome, Mild Form, Hunter's Canal Syndrome
- Trial name
- BioHunter (NCT01330277)
- Where
- 4 sites in Mexico
- Volunteers
- 11 people
- Sponsor
- CENTOGENE GmbH Rostock
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