Clinical trials: Neurological Diseases
Kinesiophobia, Acute Pain
Development of Atılım Kinesiophobia Scale
Background: Kinesiophobia or fear of movement, is defined as an excessive and irrational fear of physical movement to avoid painful injury, harm or re-injury.
- Conditions
- Kinesiophobia, Acute Pain, Chronic Pain, Fear of Movement
- Trial name
- NCT06278012
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Pain, Postoperative, Postoperative Nausea and Vomiting
Anesthetic Premedication With a Cannabis Extract (Cannapremed)
Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- Cannapremed (NCT02283281)
- Testing
- Tetrahydrocannabinol, Dummy oromucosal
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Surgical Wound, Bilateral Total Knee Arthroplasty
Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
This study will compare the effects of closed incision negative pressure dressing vs. standard of care silver dressing on lower limb swelling after bilateral primary total knee arthroplasty.
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases
- Trial name
- ENABLE (NCT04712019)
- Testing
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Where
- 6 sites in United States
- Volunteers
- 10 people
- Sponsor
- Solventum US LLC
Postpoliomyelitis Syndrome
Arm Cycling to Improve Fitness in Polio Survivors
The aim of this study is to investigate the effect of upper limb cardiovascular training on fitness, energy cost of walking, fatigue and pain in polio survivors.
- Trial name
- NCT01271530
- Testing
- Upper Limb Ergometry
- Where
- Ireland
- Volunteers
- 55 people
- Sponsor
- Royal College of Surgeons, Ireland
Chronic Pain, Knee Pain Chronic
HFIT Versus TENS Study for Chronic Low Back and Knee Pain
A high-frequency impulse therapy (HFIT) device (Enso, San Francisco, CA) is a portable device for the treatment of musculoskeletal pain.
- Conditions
- Chronic Pain, Knee Pain Chronic, Back Pain, Low
- Trial name
- NCT05821530
- Testing
- HFIT, TENS, Control
- Where
- United States
- Volunteers
- 325 people
- Sponsor
- Hinge Health, Inc
Pain, Dementia
Systematic Pain Assessment in Nursing Home Residents With Advanced Dementia
It is estimated that 45-80 % of nursing home residents have substantial pain at any given time. Residents with impaired cognition have been found to report chronic pain more often, more frequent and more severe, compared to…
- Conditions
- Pain, Dementia, Quality of Life
- Trial name
- NCT02945865
- Testing
- Pain assessment
- Where
- Norway
- Volunteers
- 112 people
- Sponsor
- Oslo Metropolitan University
Withdrawal Syndrome
Efficacy and Safety of Dexmedetomidine During Weaning From Analgesia and Sedation in PICU (TIP-15-01)
This interventional study evaluates the efficacy of dexmedetomidine during weaning from analgesic and sedative drugs in reducing the occurrence of the withdrawal syndrome in PICU.
- Trial name
- TIP-15-01 (NCT03645603)
- Testing
- Dexmedetomidine
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Intellectual Disability, Developmental Disability
Impact of Competency-Based Training and Technical Assistance Employment Outcomes of Individuals With ID/DD
Currently, there are no national pre-requisites for training to become or to be hired as an ES (Employment Specialist). Staff providing employment services have a broad range of educational and training backgrounds.
- Trial name
- NCT06586827
- Testing
- VCU-RRTC Online Course, Zoom Technical Assistance Sessions (6 total)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Virginia Commonwealth University
Head and Neck Cancer, Oral Cancer
Rehabilitation Outcomes in Head and Neck Survivors
Head and neck cancer is prevalent in Taiwan, and oral cancer is the most common location. Patients with advanced stage of the disease need extensive tumor excision with neck dissection.
- Trial name
- HNC (NCT03206242)
- Testing
- Physiotherapy
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Chang Gung Memorial Hospital
Pain, Pain Management
Ultrasound-guided Interscalene Block Versus Infraspinatus-Teres Minor Plane Block in Shoulder Arthroscopy
This study aims to compare the efficacy and safety of ultrasound-guided Interscalene block (ISB) versus Infraspinatus-Teres minor (ITM) interfacial plane block in shoulder arthroscopic surgery.
- Conditions
- Pain, Pain Management, Pain Management in Postoperative Care
- Trial name
- (ISB)-(ITM) (NCT07016386)
- Testing
- Group A: will receive an ultrasound-guided interscalene block (ISB), Group B:will receive an ultrasound-guided infraspinatus-teres minor (ITM) interfacial plane block
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Stroke
Effect of Neural Constraints on Movement in Stroke
This study investigates the effects of Tizanidine on the voluntary movement controls of the arms of participants who have had a stroke and have not had a stroke by measuring medication-induced changes in upper extremity…
- Trial name
- ENCMS (NCT06666673)
- Testing
- Tizanidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Bypass Graft Surgery
The Effect of Lavender Oil Inhalation on Pain, Anxiety and Sleep Quality After Coronary Artery Bypass Graft
Cardiovascular diseases are among the important health problems due to their increasing frequency and extensity in developed and developing countries.
- Trial name
- NCT05377983
- Testing
- Lavender oil inhalation will be performed by placing two drops of 2% lavender oil on a 5x5 cm sterile gauze cloth and asking the patient to smell it for three to five minutes
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage (ICH)
Sleep to Predict Recovery In Unconscious Patients With Acute Brain Injury
Severe brain injuries can leave people in states where they are unconscious or only partly aware, such as a coma. These conditions are common after injuries like head trauma or bleeding in the brain.
- Trial name
- SPRINT (NCT07794605)
- Where
- 2 sites in United States
- Volunteers
- 230 people
- Sponsor
- Columbia University
Cerebral Palsy
Cerebral Palsy Adult Transition Longitudinal Study
The purpose of this study is to investigate longitudinally, the walking ability of individuals with cerebral palsy who are transitioning into adulthood and to cross-sectionally examine the health status of these individuals in…
- Trial name
- CPAT (NCT02137005)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Colorado, Denver
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Stroke, Ischemic, Balance; Distorted
Effects of Bilateral Versus Unilateral Lower Limb Training on Balance and Gait Parameters in Stroke Patients
To determine the effects of bilateral versus unilateral lower limb training on balance and gait parameters in stroke patients
- Conditions
- Stroke, Ischemic, Balance; Distorted, Gait, Hemiplegic
- Trial name
- NCT05945966
- Testing
- Unilateral training group (UTG), Bilateral training group (BTG).
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Shoulder Pain
Subomohyoid vs Costoclavicular Block in Shoulder Surgery
Postoperative pain is important following arthroscopic shoulder surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.Ultrasound (US)-guided brachial plexus blocks such as…
- Trial name
- NCT05683522
- Testing
- Sub-omohyoidal Plane Block, Cervical Plexus Block, Costoclavicular Block
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Samsun University
Diabetic Peripheral Neuropathy, Neuralgia
A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy
This is a multicenter, randomized, placebo-controlled, parallel group study of EpiCept™ NP-1 Topical Cream (amitriptyline 4%/ketamine 2%) in approximately 200 patients with pain in the lower extremities due to diabetic nerve pain.
- Trial name
- NCT00476151
- Testing
- EpiCept NP-1 (4% Amitriptyline/ 2% Ketamine) Topical Cream
- Where
- India
- Volunteers
- 226 people
- Sponsor
- EpiCept Corporation
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Trigger Point Pain, Myofascial
Efficacy of Dry Needling Treatment in Myofascial Pain Syndrome
The aim of this study is to investigate the short and long-term effects of dry-needling of participants with trigger points in the upper trapezius muscle.
- Trial name
- NCT05066529
- Testing
- dry-needling
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
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