Clinical trials: Neurological Diseases
Stroke
Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability…
- Trial name
- PREVICTUS (NCT06805929)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele Roma
Aneurysmal Subarachnoid Hemorrhage
The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage
The purpose of this phase II study is to further assess the safety of tiopronin in aneurysmal subarachnoid hemorrhage(aSAH) patients in order to obtain preliminary data on the efficacy of tiopronin versus placebo in reducing…
- Trial name
- NCT01095731
- Testing
- Tiopronin
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- E. Sander Connolly
Surgery, Delirium - Postoperative
VR-Based Cognitive Stimulation Games for Delirium Prevention
This trial aims to evaluate the feasibility, safety, and acceptability of a virtual reality (VR)-based cognitive stimulation game to reduce postoperative delirium among older surgical patients at high risk due to pre-existing…
- Conditions
- Surgery, Delirium - Postoperative, Delirium
- Trial name
- NCT07641153
- Testing
- Virtual Reality Software, Virtual Reality movies, Nurse led control arm
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- The Methodist Hospital Research Institute
Facial Palsy
Self-guided Psychosocial Intervention for Facial Palsy
Facial palsy affects between 23 to 35 people per 100,000. As well as affecting an individual's appearance, it also can lead to difficulties with: eating, drinking, speaking, eyelid closure, pain and taste.
- Trial name
- NCT03943953
- Testing
- Information and Therapy Guides
- Where
- United Kingdom
- Volunteers
- 97 people
- Sponsor
- Oxford University Hospitals NHS Trust
Pain, Erythema
Compression Treatment of Superficial Vein Thrombosis
Leg compression is considered the basic treatment for superficial vein thrombosis (SVT). However, its use is more or less based on subjective experience while scientific evidence for its efficacy is lacking.
- Conditions
- Pain, Erythema, Thrombus Length, Quality of Life
- Trial name
- NCT01976637
- Testing
- no compression, compression
- Volunteers
- 80 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation (AF), Atrial Flutter
Head-to-Head (H2H) Comparison of Ambulatory Cardiac ECG Monitors in Japan
The goal of this clinical trial is to compare the yield of clinically actionable arrhythmias through the end of indicated wear duration in Zio monitor and Heartnote patch ECG devices.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Supraventricular Tachycardia (SVT), Ventricular Tachycardia (VT)
- Trial name
- Japan H2H (NCT07870837)
- Testing
- Application of ambulatory cardiac monitor
- Where
- 4 sites in Japan
- Volunteers
- 130 people
- Sponsor
- iRhythm Technologies, Inc.
Pain
HKT-500 in Adult Patients With Shoulder Pain
The objective of this study is to determine the efficacy of HKT-500 in subjects with acute shoulder pain
- Trial name
- Pain (NCT00680472)
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 35 sites in United States
- Volunteers
- 368 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Head and Neck Cancer, Oral Mucositis
The Effect of Hydrogen Water in Oral Mucositis in Head and Neck Cancer Patients After Therapy
Inpatients or outpatients diagnosed with head and neck cancer who met the inclusion and exclusion criteria were referred to the co-investigator(Dr. Chih-Jen Huang and Dr.
- Conditions
- Head and Neck Cancer, Oral Mucositis, Pain, Quality of Life
- Trial name
- NCT05913895
- Testing
- hydrogen water
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Shoulder Pain
Effectiveness of Pain Neuroscience Education vs Biomedical Education for Patients Undergoing Surgery for Shoulder Pain
BACKGROUND Shoulder pain is the third most common musculoskeletal disorder observed in primary care consultations after low back and neck pain.
- Trial name
- NCT02960477
- Testing
- Pain Neuroscience education, Biomedical Education
- Volunteers
- 84 people
- Sponsor
- University of Malaga
Traumatic Brain Injury, Brain Concussion
Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury
The main aim of this study is to evaluate the effect of vestibular rehabilitation and balance training on patients with dizziness and balance problems after traumatic brain injury.
- Conditions
- Traumatic Brain Injury, Brain Concussion, Head Injury, Dizziness
- Trial name
- VRTBI2012 (NCT01695577)
- Testing
- Multidisciplinary evaluation and VR, Multidisciplinary evaluation
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Stroke, Motor Disorders
Functional Proprioceptive Stimulation of the Upper Limbs in Stroke Patients
Parallel-group, single-blinded controlled clinical trial. The study involved stroke patients (no more than 3 points on a scale Rankin) dived of the control group and experimental group.
- Conditions
- Stroke, Motor Disorders, Upper Extremity Paresis, Muscle Weakness
- Trial name
- NCT06143475
- Testing
- FPS group, Conventional therapy group
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Analgesia , Open Renal Surgeries
Analgesic Effect of Ultrasound Guided Errector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Open Renal Surgeries.
comparison between the erector spinae block and caudal block with the aid of the of ultra sound in children as regard time of request of rescue analgesia , degree of intra and post operative pain relief , effect of hemodynamic…
- Trial name
- NCT05289401
- Testing
- ultrasound guided blocks
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome
Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome
The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment), to…
- Trial name
- NCT04285281
- Testing
- Gabapentin oral capsules, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 126 people
- Sponsor
- Universidad Europea de Madrid
Cerebral Palsy
Pain Prevalence, Distribution, Effect on Activities of Daily Life in Patients With Adolescent Cerebral Palsy
Pain is the most common secondary condition in patients with CP and the most important factor associated with reduced health-related quality of life. Pain in adolescents with CP is reported approximately 50-75%.
- Trial name
- NCT05013619
- Testing
- Circumstances of pain, Pain Questionnaire, Gross Motor Functional Classification System
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diverticulitis, Colonic
Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked.
- Trial name
- NCT06153030
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Low Back Pain, Radiculopathy
Effectiveness of Ozone Therapy Versus Pulsed Radiofrequency in Low Back Pain With Radiculopathy
Treatment selection for refractory radicular low back pain is frequently made in the absence of direct comparative evidence between competing minimally invasive options.
- Trial name
- NCT07773428
- Testing
- Intradiscal ozone therapy, Pulsed radiofrequency
- Where
- Oman
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Pain, Anxiety
Effect of Different Animal Interventions on Pain and Anxiety Levels Due to Port Catheter Needle Entry
This study was conducted to examine the effect of parrot, fish, and turtle therapies on procedural pain and anxiety levels associated with implantable venous port catheter needle insertion in patients receiving palliative care.
- Trial name
- NCT07238361
- Testing
- Sultan Parrot Therapy (Pet Therapy), Betta Fish Therapy (Pet Therapy), Red-Eared Slider Turtle Therapy (Pet Therapy)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University
Functional Neurological Disorder, Functional Movement Disorder
Efficacy of the Multidisciplinary Treatment to the Quality of Life of With Functional Movement Disorders
Randomized-clinical trial of multidisciplinary approach versus psychoeducation in patients with functional movement disorders: impact to their quality of life and their caregivers' quality of life.
- Trial name
- NCT05634486
- Testing
- Multidisciplinary therapeutic approach (physiotherapy plus cognitive-behavioral therapy)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
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