Clinical trials: Neurological Examination
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Postmenopausal Syndrome, Muscle Weakness
The Bilateral Deficit Phenomenon, Functional and Dynamometric Assessment in Postmenopausal Women
The bilateral deficit phenomenon (BLD) is defined as an inability of the neuromuscular system to generate maximal force when two homonymous limb operate simultaneously (bilateral contraction) with respect to the force developed…
- Trial name
- NCT02434185
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Low Blood Pressure, Delirium
Vasopressor SAT Study
To assess the impact of daily awakening from sedation on the amount of vasoactive medication required in the ICU. The hypothesis of this proposal is that the amount of vasoactive drug required to maintain an adequate mean…
- Conditions
- Low Blood Pressure, Delirium, Critical Illness
- Trial name
- NCT03182335
- Testing
- sedation awakening trial
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Chicago
Drepanocytosis, Chronic Neurological Deficiency
Transfusion Exchanges and Cognition in Sickle Cell Disease
DREPA-COG is an observational study evaluating the effect of exchange transfusions on cognitive function in adults with severe sickle cell disease (SS or Sβ0).
- Trial name
- DREPA-COG (NCT07168447)
- Where
- 6 sites in France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier St Anne
Cardiovascular Diseases, Cardiovascular Diseases Risk
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Cor360 is an observational study evaluating whether extended wearable electrocardiogram (ECG) data can support broad-spectrum cardiac phenotyping and risk assessment beyond conventional single-purpose ambulatory rhythm…
- Conditions
- Cardiovascular Diseases, Cardiovascular Diseases Risk, Cardiac Conduction System Disease, Bundle/Fascicular Abnormalities
- Trial name
- Cor360 (NCT07775976)
- Testing
- COR Wearable ECG Monitoring, Cor360 Clinician-Facing Decision-Aid Reporting
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Cryopyrin Associated Periodic Syndrome
Adult Outcomes of Children With CAPS
The patients included in this study were followed up in the Internal Medicine and Paediatrics Departments of the Lille CHU, the Paediatric Rheumatology and Immunology Department of the Necker Enfant Malade Hospital in Paris and…
- Trial name
- CAPS (NCT04856540)
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Lille
Diaphragm Elevated, Paresis
FOT Assessment of Hemi-diaphragm Dysfunction After Upper Extremity Nerve Blocks
Upper extremity nerve blocks of the brachial plexus using local anesthetic can inadvertently affect the ipsilateral phrenic nerve and result in hemidiaphragm dysfunction.
- Trial name
- NCT04005235
- Testing
- Thorasys Tremoflo C-100 Airwave Oscillometry System (FOT)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Nova Scotia Health Authority
Bladder Cancer, Flexible Cystoscopy
Assessment Of Bladder Tumors Stage And Grade By Outpatient Flexible Cystoscopy Performed By Urology Resident
This will be a prospective trial comparing the perspective gross morphological of bladder tumor assessment done by outpatient flexible cystoscopy performed by resident, inpatient rigid cystoscopy done by senior staff and their…
- Conditions
- Bladder Cancer, Flexible Cystoscopy, Non-muscle Invasive Bladder Cancer (NMIBC), Pain, Postoperative
- Trial name
- NCT03148158
- Testing
- Cystoscopy
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Retinitis Pigmentosa, Age-related Macular Degeneration
Visual and Functional Assessment in Low Vision Patients
Vision testing is a fundamental part of every optometry and ophthalmology assessment. Traditional vision testing charts are not able to measure vision below a certain level.
- Conditions
- Retinitis Pigmentosa, Age-related Macular Degeneration, Optic Nerve Pathology, Inherited Retinal Dystrophies
- Trial name
- NCT01876147
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Oxford
Neovascular Age-related Macular Degeneration
Study of Innovative Multimodal Imaging Biomarkers to Predict Anatomical Outcome in Naive Patients With wAMD Treated With Brolucizumab.
The purpose of this study was to identify innovative early imaging parameters as predictors of the long-term clinical response to brolucizumab in terms of fluid resolution in patients with wet Age-related Macular Degeneration…
- Trial name
- IMAGINE (NCT04774926)
- Testing
- Brolucizumab
- Where
- 20 sites in Italy
- Volunteers
- 122 people
- Sponsor
- Novartis Pharmaceuticals
Physical Endurance
Isometric Core Muscle Endurance in Healthy Active and Non-active Working Age Populations
Objectives: The purpose of this study was to investigate a possible correlation between core muscle endurance and participants' age in healthy adult population.
- Trial name
- NCT04209335
- Testing
- isometric core muscle endurance testing
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hanna Holmberg
Sarcopenia
Sarcopenia and Combined-modality Exercise
This study examined the effects of combined-modality exercise training (resistance, endurance, flexibility and balance) on muscle mass, muscle function and physical activity in community-dwelling elderly living in Jamaica who had…
- Trial name
- NCT04806152
- Testing
- High intensity exercise, Usual care home exercise
- Where
- Jamaica
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Postoperative Pain
Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain
Investigators will evaluate preamputation cryoanalgesia on pain, mobility, opioid use and general physical and emotional disability using a pilot randomized trial design, to explore the amount and variability of improvement on…
- Trial name
- NCT06284109
- Testing
- Cryoanalgesia
- Where
- United States
- Sponsor
- The Cleveland Clinic
Ventral Hernia, Ventral Incisional Hernia
The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery
Ventral hernia repair is among the most common operations performed in the United States each year, yet the great majority of patients receive no structured rehabilitation for the persistent pain, weakness, and functional loss…
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
- Trial name
- IMPACT (NCT07145099)
- Testing
- PT Group, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Balance Control
Impact of Physical Activities on Balance in Patient With Strabismic Amblyopia
The aim of this study is to determine the effect of physical activities on balance in patient with amblyopia after strabismus surgery.
- Trial name
- NCT06758063
- Testing
- exercises therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid
Myofascial Pain Syndrome (MPS), Neck Pain
Dual Frequency Low-Level Laser Therapy in Myofascial Trigger Points of Upper Trapezius
The goal of this clinical trial is to determine whether dual frequency low-level laser therapy can reduce pain, improve function, and increase neck movement in patients with myofascial trigger points in the upper trapezius…
- Conditions
- Myofascial Pain Syndrome (MPS), Neck Pain, Myofacial Trigger Points
- Trial name
- DF-LLLT-MTP-UT (NCT07137728)
- Testing
- Red Low-Level Laser Therapy, Infrared Low-Level Laser Therapy, Dual Frequency Low-Level Laser Therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Lahore
Derangement; Low Back
Cyriax Manipulation in Lumbar Derangement Syndrome
the objective of the study was to determine the effect of Cyriax manipulation for Pain, range of motion and quality of life in lumbar internal derangement radiculopathy in single physical therapy session.
- Trial name
- NCT04082065
- Testing
- conventional physical therapy, cyriax lumber manipulation group
- Where
- Pakistan
- Volunteers
- 43 people
- Sponsor
- Riphah International University
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Pain, Intractable
Phase III Clinical Trial of Fentanyl Transdermal Matrix Patch, in the Management of Chronic Intractable Pain- Assessment of Effectiveness, Safety and Pharmacokinetics
The purpose of this study is to verify the effectiveness, and safety in Japanese patients with chronic intractable pain after 4-week medication of fentanyl transdermal matrix patches containing either 12.5 mcg/hr, 25 mcg/hr, 50…
- Trial name
- NCT00216684
- Testing
- fentanyl
- Volunteers
- 139 people
- Sponsor
- Janssen Pharmaceutical K.K.
Frailty, Fall
Validation and Application of a Multi-dimentional Frailty Assessment Tool-Cohort Intervention and Follow up
We aim to (1) use a multifaceted, frailty assessment model. (2) use randomized controlled trials to deal with and intervene with cross-field, multi-faceted and intelligent remote management strategies for the elderly with…
- Conditions
- Frailty, Fall, Sarcopenia
- Trial name
- NCT05731167
- Testing
- Multidomain frailty prevention method, Regular follow up
- Where
- Taiwan
- Volunteers
- 216 people
- Sponsor
- National Taiwan University Hospital
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