Clinical trials: Neurological Examination
Inflammation, Aging
Inflammation Control For Elders: ICE Study
This study will be the first to test whether a selected anti-inflammatory agent, methotrexate, reduces inflammation in a human body, improve cognitive and physical function, and reduce pain levels in older adults at risk for…
- Trial name
- ICE (NCT02079948)
- Testing
- Methotrexate + Folic Acid, Functional MRI Experimental Tasks, Muscle Biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Myasthenia Gravis, Neuromuscular Manifestations
Expediting Myasthenia Gravis (MG) Diagnostic Evaluation: A Novel, Proof-of-Concept for Undiagnosed, Symptomatic Patients That Uses Social Media Targeting and Self-Assessment
This is a fully remote, site-less, prospective, observational study enrolling adults in the United States (excluding U.S. territories) with undiagnosed neuromuscular symptoms.
- Conditions
- Myasthenia Gravis, Neuromuscular Manifestations, Neuromuscular Diseases
- Trial name
- NCT06381284
- Testing
- Social media recruitment, Self-Assessment, Follow-up
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- ZS Associates
Neuromuscular Diseases, Neurologic Disorder
Multisystem and Autonomic Complications of NMD on Long-term NIV
This exploratory observational study evaluates autonomic function using measures including heart rate variability in adults with childhood-onset neuromuscular and neurological disorders (NMD) who use non-invasive ventilation…
- Trial name
- NCT04100993
- Testing
- No intervention used
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Healthy
Assessment of Upper Limb Motor Performance Using an Interface With Haptic Feedback
The purpose of the study is to test an evaluation environment based on a device that has the ability to provide the user with tactile (haptic) sensations.
- Trial name
- NCT05819047
- Testing
- Functional test with a haptic device
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Entre Rios
Pain
Pain Management of Intensive Care Unit Patients
The purpose of this study is to evaluate the effect of an algorithm, where ICU patients pain are assessed systematically with valid pain assessment tools and where pain is treated after pain intensity score.
- Trial name
- NCT01599663
- Testing
- Pain management algorithm
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Ostfold Hospital Trust
Inguinal Hernia, Developmental Delay Disorders
Feasibility Study for PANDAS
We have been asked to participate in the Pediatric Anesthesia NeuroDevelopmental Assessment Study (PANDAS), which is a study to compare neurocognitive functions in sibling pairs: one of whom had exposure to anesthesia during…
- Trial name
- NCT00754897
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Children's Hospital of Philadelphia
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Pain
Pain Assessment During General Anesthesia
During general anesthesia, two treatments are used : hypnotic and opioid treatment. Opioid treatment is used for pain assessment.
- Trial name
- DOLANS (NCT01303471)
- Testing
- opioid (remifentanyl)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cerebral Palsy, Motor Dysfunction
Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Children With Cerebral Palsy
The investigators design a Multi-center randomized, control study to evaluate the therapeutic effect of the scalp acupuncture treatment for motor dysfunction in children with cerebral palsy by using the following outcomes: motor…
- Conditions
- Cerebral Palsy, Motor Dysfunction, Acupuncture
- Trial name
- NCT03921281
- Testing
- scalp acupuncture treatment, Rehabilitation Treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Fudan University
Pain Control
Dexamethasone and Etoricoxib for Pain Prevention Following Periodontal Surgery
The purpose of this study is to investigate whether preemptive medication with dexamethasone or etoricoxib provides better pain management and control than placebo following periodontal surgery.
- Trial name
- NCT00970112
- Testing
- Open Flap Debridement
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Intellectual Disabilities (F70-F79), Neurologic Manifestations
Functional Skills Training for Supermarket Shopping Using NFC Technology in People With Intellectual Disabilities
The general objective of the "Compra con-Migo" project is to evaluate the impact of a technological tool based on NFC (Near Field Communication) technology on the development of cognitive and instrumental skills necessary to…
- Trial name
- NCT07659457
- Testing
- App training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidade da Coruña
Acute Post-operative Pain, Cholecystectomy, Laparoscopic
Optimizing Pain Management Following Laparoscopic Cholecystectomy RCT
evaluating the two final steps we added to optimize post laparoscopic cholecystectomy pain management.
- Conditions
- Acute Post-operative Pain, Cholecystectomy, Laparoscopic, Pain Assessment Pain Intensity, Pain Intensity
- Trial name
- Pain (NCT05214157)
- Testing
- active gas aspiration
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Zagazig University
Chronic Low-back Pain
COgNitive FuncTional Therapy+ for Chronic Low Back paIn
This study is a patient-blinded 2-arm randomized controlled trial (RCT) assessing the effectiveness (in the short and long term) as well as total healthcare costs of a CFT+ (a combined physiotherapist/psychologist intervention)…
- Trial name
- CONFeTTI (NCT04399772)
- Testing
- Cognitive Functional Therapy+ pathway, Interdisciplinary pain management pathway
- Where
- Denmark
- Volunteers
- 133 people
- Sponsor
- Odense University Hospital
Movement Disorders, Parkinson's Disease
A Study of Movement Disorders Using the QMAT At-Home Testing Device
Background: Parkinson s disease (PD) affects half a million Americans, causing slow movements, tremors, stiffness, and trouble walking.
- Trial name
- NCT01905839
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Down Syndrome
Correlations Phenotype / Genotype in Down Syndrome
The purpose of this study is to correlate phenotype and genotype of Down syndrome patients in order to identify the biochemical reactions involved in their mental retardation and their other phenotypic characteristics.
- Trial name
- INTREPID (NCT01034280)
- Where
- France
- Volunteers
- 524 people
- Sponsor
- Institut Jerome Lejeune
Neurorehabilitation, Nervous System Diseases
The Use of Modern Technologies in Neurorehabilitation
Early conventional rehabilitation improves the functioning of patients with neurological diseases. However, recovery is not always satisfactory.
- Conditions
- Neurorehabilitation, Nervous System Diseases, Biomedical Enhancement, Physical Activity
- Trial name
- NCT05550987
- Testing
- Rehabilitation program with the use of mechanical vibration using the Vibramoov device and conventional physiotherapy, Rehabilitation program with gait training using the Ekso GT exoskeleton and conventional physiotherapy, Rehabilitation program with the use of gait training with the use of a RoboGait stationary robot and conventional physiotherapy.
- Volunteers
- 120 people
- Sponsor
- University of Rzeszow
Neck Pain
The Effects of Dry Needling on the Superficial Neck Musculature
The term myofascial pain refers to the existence of myofascial trigger points (MTP), which are defined as hypersensitive points in a tense band of skeletal muscle, which can cause referred pain or autonomous phenomena.
- Trial name
- NCT04060004
- Testing
- Dry needling, Electrotherapy + therapeutic exercise
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valladolid
Memory Disorders, Mild Cognitive Impairment
Physical Exercise for Prevention of Dementia
The principal aim of this study is to verify whether a program of supervised, multimodal physical exercise improves cognitive function and/or reduces the rate of cognitive decline in older adults
- Conditions
- Memory Disorders, Mild Cognitive Impairment, Aging
- Trial name
- EPD (NCT02236416)
- Testing
- Intervention group, Control group
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Molise
Otalgia, Otitis Media
Validating and AI Software for Assessment of Children With Ear Concerns
The goal of this observational study is to determine if the Glimpse machine learning algorithm can accurately assess ear diseases in children.
- Conditions
- Otalgia, Otitis Media, Otitis Media Effusion
- Trial name
- NCT07243093
- Volunteers
- 658 people
- Sponsor
- Glimpse Diagnostics, Inc.
Brain Concussion, Vestibular Disorder
Portable Mixed Reality-based Platform for Assessment of Progress in Multisensory Rehabilitation Strategies Post-TBI
The goal of this comparative pilot study is to provide evidence that Praxis, a portable testbed with low-cost wearable sensors and a mixed reality environment, can deliver effective multisensory rehabilitation exercises with…
- Conditions
- Brain Concussion, Vestibular Disorder, Cognition Disorder, Mild Traumatic Brain Injury
- Trial name
- Praxis (NCT06314464)
- Testing
- Praxis, Supervised cardiovascular exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- BlueHalo
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