Clinical trials: Neurological Outcome
Inguinal Hernia, Chronic Pain
Trigger-point Blockade in Persistent Pain After Open Groin Hernia Repair
Groin hernia repair is a common procedure performed in approximately 2,000 patients per one million inhabitants. Severe chronic pain following groin hernia repair is seen in 2-5% of the patients indicating that a large number of…
- Trial name
- Trigger-open (NCT02065219)
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cavernous Malformation, Cerebral, Cavernous Angioma
Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy
Cerebral cavernous malformation (CCM)-related epilepsy (CRE) impairs the quality of life in patients with CCM. Patients could not always achieve seizure freedom after surgical resection of the lesion, suggesting an inadequate…
- Conditions
- Cavernous Malformation, Cerebral, Cavernous Angioma, Cavernous Hemangioma, Cavernous Hemangioma of Brain
- Trial name
- CRESS (NCT04076449)
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- yuanli Zhao
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Video-Assisted Thoracic Surgery
Quality of Postoperative Recovery (QoR-15T) in Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive technique that provides faster recovery after thoracic surgery.
- Trial name
- NCT06558331
- Testing
- Bupivacaine 0,25%, Bupivacaine 0,375%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Rehabilitation, Treatment Outcome
Effects of Exercise Therapy and Soft Brace on Knee Osteoarthritis
The primary aim of the study is to investigate the effects of supervised exercise therapy and education on the immediate response to using a soft knee brace in patients with knee osteoarthritis (OA).
- Conditions
- Rehabilitation, Treatment Outcome, Pain, Knee Brace
- Trial name
- NCT03949400
- Testing
- Exercise therapy and education.
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College of Northern Denmark
Labor Pain
Failure of Vaginal Delivery After Induction
The study will compare the number of women who deliver vaginally after artificial initiation of labor pains(i.e. induction of labor) by two methods.
- Trial name
- NCT02758340
- Testing
- Misoprostol, foley's balloon catheter
- Where
- Pakistan
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Karachi Medical and Dental College
Birth Outcome, Adverse, Self Efficacy
The Door to the Womb at Birth: Haptonomy
Purpose: This study aimed to examine the effect of haptonomy application on the expectant mother's birth expectations, experiences, birth self-efficacy, birth memory and reminder during labor.
- Conditions
- Birth Outcome, Adverse, Self Efficacy, Memory Impairment, Pregnancy Related
- Trial name
- NCT06508554
- Testing
- Haptonomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Trakya University
Intellectual Disability, Perceptual Disorders
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
The purpose of this study is to determine the relationships between sedative exposure during pediatric critical illness and long-term neurocognitive outcomes.
- Conditions
- Intellectual Disability, Perceptual Disorders, Memory Disorders
- Trial name
- RESTORE-cog (NCT02225041)
- Where
- 31 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Intraoperative Pain
Management of Indwelling Labor Epidural Catheters for Cesarean Delivery
This is a prospective observational study that will survey patients who had an indwelling labor epidural catheter and subsequently underwent cesarean delivery.
- Trial name
- NCT07366307
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Anesthesia, Analgesia
Genetic Variants and Non-genetic Variables and Postoperative Nausea and Vomiting
Prospective observational study to analyse the association of non-genetic variables as well as genetic variants of candidate genes with the incidence of postoperative nausea and vomiting (PONV).
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT03490175
- Where
- Switzerland
- Volunteers
- 2,778 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Osteoarthritis, Knee
Antibiotic Loaded Bone Cement in Prevention of Periprosthetic Joint Infections in Primary Total Knee Arthroplasty
Introduction: The current evidence on the efficacy of Antibiotic Loaded Bone Cement (ALBC) in reducing the risk of periprosthetic joint infections (PJI) after primary joint reconstruction is insufficient.
- Trial name
- ALBA (NCT04135170)
- Testing
- ALBC vs plain bone cement
- Where
- Norway
- Volunteers
- 9,172 people, healthy volunteers welcome
- Sponsor
- The Norwegian Arthroplasty Register
Epidural Analgesia, Mechanical Ventilation
Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery
Elderly patients have a higher incidence of morbidity and mortality due to the interaction of various factors such as decreased physiological reserves, concomitant comorbidities, multiple drug use, cognitive dysfunction, and…
- Conditions
- Epidural Analgesia, Mechanical Ventilation, Postoperative Complications, Analgesia
- Trial name
- NCT04708080
- Testing
- thoracic epidural analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Muscle Atrophy, Myotonia
Electromyostimulation (EMS) of Astronauts in Spaceflight (Easymotion-2)
This is a prospective spaceflight study involving an investigational non-risk device called the EasyMotionSkin for whole body electric muscle (myo) stimulation (WB-EMS) onboard the International Space Station (ISS).
- Conditions
- Muscle Atrophy, Myotonia, Stiffness; Spine, Exercise Overtraining
- Trial name
- Easymotion-2 (NCT06492057)
- Testing
- Electromyostimulation (EMS), Myoton, Electromyography (EMG)
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Low Back Pain
Back Pain - Linking Phenotype to Pain Mechanism and Outcome.
To investigate whether different clinical, psychophysical and neurophysiological phenotypes can be identified among low back pain patients
- Trial name
- NCT04433299
- Testing
- no intervention, observational
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Low Back Pain
The Effect of Manipulations of the Lumbar Spine on Six Different Outcome Measures
1. Evaluation of the effect of a chiropractic adjustment (Manually Assisted Mechanical Force)on 2. surface Static EMG 3. Paraspinal cutaneous temperature 4. Range of Motion 5. Dynamic EMG 6.
- Trial name
- NCT00739570
- Testing
- AAI signature IV AMCT
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Pain, Stenosis
Clinical Outcome Study of the Triad Allograft for Posterior Lumbar Fusion
The purpose of the study is to prospectively measure pain, function, and patient satisfaction in 70 consecutive patients treated by lumbar fusion using the Triad allograft.
- Conditions
- Pain, Stenosis, Spondylolisthesis
- Trial name
- NCT00205101
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Varicocele, Pain
"Outcome of Varicocelectomy on Normal Semen in Patients Complaining of Orchialgia
varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not.
- Conditions
- Varicocele, Pain, Fertility Issues
- Trial name
- NCT04509869
- Testing
- varicocelectomy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Surgery, Surgery--Complications
Patterns and Outcomes of Neurosurgery in England Over a Five-year Period
Neurosurgical practice has seen many important changes over several decades with advances in treatments and the types of patients treated.
- Conditions
- Surgery, Surgery--Complications, Neurological Morbidity, Neurological Diseases or Conditions
- Trial name
- NCT05097066
- Testing
- Neurosurgical procedure
- Volunteers
- 371,418 people, healthy volunteers welcome
- Sponsor
- University of Leeds