Clinical trials: Neurological Outcome
Preterm, Extreme Prematurity
Effectiveness of Home Based Early Intervention of Extremely Premature Infant by Parent
This study is to prove the effectiveness of home based early intervention of extremely premature infant by Parent.
- Conditions
- Preterm, Extreme Prematurity, Early Intervention, Developmental Delay
- Trial name
- NCT05334550
- Testing
- Home Based Early Intervention by Parent
- Volunteers
- 110 people
- Sponsor
- Samsung Medical Center
Muscle Spasticity as a Result of Spinal Cord Injury
Effect of Cannabinoids on Spasticity and Neuropathic Pain in Spinal Cord Injured Persons
This study is being conducted to study the effect of nabilone (a synthetic cannabinoid)on spasticity in spinal cord injured persons.The study will be a phase 2, randomized, placebo-controlled crossover study.
- Trial name
- NCT01222468
- Testing
- nabilone 0.5 mg
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
C10.228.140.140.254
The Socioeconomic Status and Child Characteristics on the Physical Therapy Outcome in Children With Spastic Cerebral Palsy
The main outcome of physical therapy interventions is the progress of gross motor functions which result from the interactions between many factors not limited to physical, medical or surgical interventions but also including…
- Trial name
- NCT04160403
- Testing
- physical therapy intervention
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zeinab Hussein
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Sleep Deficiency and Stroke Outcome
Deficient sleep duration and sleep disturbances - such as insomnia, sleep disordered breathing (SDB) and restless legs syndrome (RLS)- are associated with hypertension and cardio-cerebrovascular morbidity and mortality.
- Conditions
- Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders, Insomnia, Restless Legs Syndrome
- Trial name
- NCT02559739
- Where
- 2 sites in Switzerland
- Volunteers
- 447 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
1. VLBW Infants, 2. Hypotension
Neurological Outcome of VLBW Infants With Early Hypotension
Comparison of short and long term neurological outcome of VLBW infants with and without early onset hypotension required intervention.
- Trial name
- NCT00266422
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
Low Back Pain
dorsaVi Back Pain and Movement Registry
This study will compare patients with low back pain (LBP) to age and gender matched controls to determine if there are differences between the two groups related to: range of movement, secondary outcomes (level of disability…
- Trial name
- BPAM (NCT03001037)
- Where
- 3 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- dorsaVi Ltd
Arthroplasty, Replacement, Knee, Blood Loss, Surgical
Early Outcome of Simultaneous Bilateral Total Knee Replacement With and Without Tourniquet
This randomized controlled trial compared early outcomes after replacement of both knees during the same operation, with and without tourniquet use.
- Conditions
- Arthroplasty, Replacement, Knee, Blood Loss, Surgical, Pain, Postoperative
- Trial name
- NCT07905495
- Testing
- Simultaneous Bilateral Total Knee Replacement with Tourniquet, Simultaneous Bilateral Total Knee Replacement without Tourniquet
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shifa International Hospital
Labor Pain
Failure of Vaginal Delivery After Induction
The study will compare the number of women who deliver vaginally after artificial initiation of labor pains(i.e. induction of labor) by two methods.
- Trial name
- NCT02758340
- Testing
- Misoprostol, foley's balloon catheter
- Where
- Pakistan
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Karachi Medical and Dental College
Consciousness Disorders, Communication
Analysis of Vital, Facial and Muscular Responses Front to Music or Message in Coma, Vegetative State or Sedated Patients
Objectives: (1) To check music or voice message influence on vital signs, facial expressions or muscular tonus of coma, vegetative or sedated patients; (2) To connect the existence of patient's responsiveness with the Glasgow…
- Conditions
- Consciousness Disorders, Communication, Intensive Care
- Trial name
- NCT01141790
- Testing
- Music and voice message
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Shoulder Pain, Head and Neck Cancer
Reliability and Validity of Patient Reported Outcome Measures in Head and Neck Cancer
This study will utilize Rasch analysis to study the construct validity and reliability of five shoulder-related patient-reported outcome measures in patients reporting shoulder impairment following surgery for head and neck…
- Trial name
- NCT02554968
- Testing
- Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 182 people
- Sponsor
- Mayo Clinic
Parkinson Disease
neuroQWERTY: a Transparent Patient-centered Outcome Method to Quantify Parkinsonian Motor Signs for Drug Trials
The motor impairment produced by Parkinson's disease (PD) is a significant and debilitating part of the condition. Current methods to evaluate this impairment rely on subjective examinations.
- Trial name
- neuroQWERTY (NCT02522065)
- Where
- 6 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundación de investigación HM
High Risk Non-cardiac Surgery, Death
Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery
Cerebral desaturations occur frequently in patients undergoing non-cardiac surgery. The definition of what constitutes a cerebral desaturation, the incidence of the phenomenon, the association between desaturations and…
- Conditions
- High Risk Non-cardiac Surgery, Death, Delirium, Kidney Injury
- Trial name
- NCT01838733
- Testing
- Observational study
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Manitoba
Liver Cirrhosis
Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome
The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power…
- Trial name
- SLIM (NCT03584204)
- Testing
- imaging
- Where
- 3 sites in Germany, Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital, Bonn
Cardiac Arrest, Neurological Outcome
Early Neuroprognostication After OHCA
This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier…
- Conditions
- Cardiac Arrest, Neurological Outcome, EEG, CT
- Trial name
- NCT05706194
- Testing
- Early neurological prognostication with biomarkers, EEG and CT
- Where
- 4 sites in Finland, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Lund University
Neck Pain
C3 Laminectomy With Cervical Laminoplasty
1. Background In cervical stenosis, cervical laminoplasty from the third to sixth cervical vertebrae is widely used. However, the muscles attached to the C2, which play an important role in the movement of our neck, are…
- Trial name
- NCT06374680
- Testing
- laminectomy at C3 level
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Subacute and Chronic Non-specific Low Back Pain
Comparison of the Effectiveness of 2 Manual Therapies on Functional Outcome in Sub-acute and Chronic Non-specific Low Back Pain
The purpose of this study is to determine whether a standardised osteopathic manipulative treatment is more effective than a placebo of osteopathic manipulative treatment, in sub-acute and chronic non-specific low back pain on…
- Trial name
- LC OSTEO (NCT02034864)
- Testing
- Osteopathic manipulative treatment
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Fractures, Gait, Unsteady
Comparison of Sliding Hip Screw to Intra Medullary Nailing in the Treatment of Intertrochanteric Hip Fracture
Shortening of the abductor lever arm is a particular concern with the SHS, and the resultant biomechanical alterations may impair gait, including decreased cadence, gait speed and increased double support time on the injured…
- Conditions
- Hip Fractures, Gait, Unsteady, Function
- Trial name
- NCT03906032
- Testing
- TFNA IM Nail, Sliding hip screw
- Where
- Ireland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Waterford
EEG With Periodic Abnormalities, EEG With Abnormally Slow Frequencies
Continuous EEG Randomized Trial in Adults
Continuous video-EEG monitoring (cEEG) significantly improves seizure or status epilepticus detection in patients in intensive care units (ICUs), and is recommended for patients with consciousness impairment.
- Conditions
- EEG With Periodic Abnormalities, EEG With Abnormally Slow Frequencies, Coma, Outcome, Fatal
- Trial name
- CERTA (NCT03129438)
- Testing
- continuous EEG (cEEG), routine EEG (rEEG)
- Where
- 4 sites in Switzerland
- Volunteers
- 404 people
- Sponsor
- Andrea Rossetti, MD
Pain
A Trial Assessing the Outcome of Celecoxib Administration Versus Placebo Following Anterior Cruciate Ligament (ACL) Reconstruction
The aim of this study is to directly compare the clinical outcomes of both the celecoxib and placebo groups following anterior cruciate ligament (ACL) reconstruction. The study will have short and long term goals.
- Trial name
- NCT01186887
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Pain, Fever
Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen
Subcutaneous perfusion is an underused technique, the effectiveness of which has been demonstrated. A number of drugs of different therapeutic classes, including morphine, have a good level of scientific evidence for use by this…
- Conditions
- Pain, Fever, Drug Effect, Drug Reaction
- Trial name
- APAPSubQ (NCT03635684)
- Testing
- Acetaminophen
- Where
- Lebanon
- Volunteers
- 31 people
- Sponsor
- Saint-Joseph University