Clinical trials: Neurological Outcome
Postoperative Cognitive Dysfunction
Cerebral Oximetry and Neurological Outcomes in Aortic Arch Surgery Patients
The investigators hypothesize that early intervention to optimize regional cerebral oxygenation detected by cerebral oximetry monitoring during deep hypothermic circulatory arrest (DHCA) for patients undergoing aortic surgery…
- Trial name
- NCT01149148
- Testing
- INVOS Somanetics Cerebral Oximeter
- Volunteers
- 25 people
- Sponsor
- University of Michigan
Stroke, Stroke, Acute
The Enriched Environment as an Integrated Tool in the Ward Setting
The goal of this longitudinal interventional study is to integrate the enriched environment (EE) in the context of the Neurology Clinic ward of the General Hospital - University of Padua, by verifying its effectiveness and impact…
- Trial name
- ENVIRONMENT (NCT06233682)
- Testing
- Enriched environment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Padova
Chronic Pain
Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain
The purpose of this study is to obtain real-world clinical outcome data for the Algovita Spinal Cord Stimulation system when used, on-label, according to the applicable directions for use.
- Trial name
- NCT02373540
- Testing
- Algovita Spinal Cord Stimulation system
- Where
- 18 sites in United States, Germany
- Volunteers
- 91 people
- Sponsor
- Nuvectra
Labor Pain
Outcome of Combined Tramadol and Paracetamol Versus Pentazocine as Labour Analgesia Among Parturients
Labour is a very painful experience and epidural analgesia is considered the gold standard for pain relief in labour. Epidural scarcity, cost and shortage of skilled personnel to administer it is a limitation to it's usage in…
- Trial name
- OCTAPPENALA (NCT05565274)
- Volunteers
- 166 people
- Sponsor
- Federal Medical Centre, Yenagoa
Postoperative Delirium
Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery
Postoperative delirium (POD) is the most common adverse neurologic complication that can occur in patients of any age. Its incidence varies across age groups and is substantially influenced by patient-related risk factors.
- Trial name
- NCT04707794
- Testing
- Sevoflurane, Desflurane
- Where
- 2 sites in India
- Volunteers
- 270 people
- Sponsor
- Sir Ganga Ram Hospital
Brain Injury
Comparison of Two Initial Evaluation Scales of the Severity of Brain Injury Adults Patients on the Neurological Outcome at 6 Months
Prospective cohort study. Any patient with potential cerebral injured (medical or traumatic) will be included in the study, regardless of its severity, history, the presence of anticoagulant or antiagrégant.
- Trial name
- CASSANDRA (NCT03157453)
- Where
- France
- Volunteers
- 367 people
- Sponsor
- Poitiers University Hospital
Neurological Disease
Investigational Biomarkers for Neurological Immune-related Adverse Events
Neurological immune-related adverse events (n-irAEs) are an emerging group of disorders of patients with cancer treated with immune checkpoint inhibitors, presenting with heterogeneous clinical manifestations and of uncertain…
- Trial name
- NFL-ICI (NCT05969379)
- Testing
- Analysis of biomarkers and their correlation with clinical characteristics and outcome
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Disabilities Physical, Sensory Disorder
Systematic Development and Test-Retest Reliability of EISA
The purpose of this proposed study, is the development and validation of EISA, a Self-report outcome measurement tool, for assessing the satisfaction of everyday functional needs, for consumers using Electronic Assistive Devices…
- Trial name
- EISA (NCT04797754)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Pittsburgh
Carpal Tunnel Syndrome
Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery
This study is focused on comparing patients' pain scores on a visual analogue scale (VAS) and the difference in analgesics use post-operatively (with the same prescription defining only the maximum frequency) between lidocaine…
- Trial name
- NCT02315573
- Testing
- Wrist block anesthesia
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- St. Mary's Research Center, Canada
Cardiac Arrest
CT Perfusion (CTP) for Assessment of Poor Neurological Outcome in Comatose Cardiac Arrest Patients
ABSTRACT Brief Overview: Neurological assessment of comatose cardiac arrest patients (CCAP) is challenging because most of these patients are treated with sedatives and therapeutic hypothermia that prevent complete…
- Trial name
- CANCCAP (NCT04323020)
- Testing
- CT Perfusion
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Manitoba
Head Trauma
Preventive Sodium Lactate and Traumatic Brain Injury
The goal of this study is to evaluate the effect of preventive intravenous infusion of half molar sodium lactate on the onset of hypertensive intracranial episodes in severe head trauma.
- Trial name
- NCT00995683
- Testing
- half molar sodium lactate, isotonic sodium chloride
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Enhanced Recovery After Surgery, Hospital Stay
The Impact of Enhanced Recovery After Surgery in Orthognathic Surgery
Aim: Orthognathic surgeries are generally associated with blood loss, swelling, postoperative nausea vomiting (PONV), and pain. The aim of this study is to improve postoperative outcome in patients undergoing orthognatic…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Postoperative Nausea and Vomiting, Pain, Postoperative
- Trial name
- NCT04596774
- Testing
- Traditional Approach, Enhanced Recovery After Surgery (ERAS) Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Osteoarthritis, Knee
Transcutaneous Vagal Stimulation in Knee Osteoarthritis
This study will evaluate the efficacy of Transcutaneous Vagal Stimulation in people whit knee osteoarthritis.
- Trial name
- TRAVKO (NCT04381624)
- Testing
- Exercise program
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Universidad de La Frontera
Delirium
Subclinical Delirium and Clinical Outcome
Delirium has been associated with clinical outcomes in critical care setting. However, its subclinical form has not been investigated. The investigators aimed to establish the association of subclinical delirium with outcome.
- Trial name
- ZZH-2 (NCT01616914)
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Jinhua Central Hospital
Seroma
The QUILT Study: Quilting Sutures in Patients Undergoing Breast Cancer Surgery
Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires treatment and…
- Trial name
- QUILT (NCT05272904)
- Testing
- Quilting, Conventional wound closure
- Where
- Netherlands
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Canisius-Wilhelmina Hospital
Agitation, Craniotomy
Agitation in Post Operative Neurosurgical Patients
Agitation is a significant clinical issue in anesthesiology and critical care medicine. Several studies have carried out to survey the epidemics of agitation in post-anesthesia care unit and intensive care unit, and results…
- Trial name
- NCT00590499
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Frailty, Delirium Confusional State
Patients With Long-stay at ICU: Factors and Evaluation - Feasibility Study
Every year, many critically ill patients are admitted to an intensive care unit (ICU). Most stay only a few days, but a smaller group stays much longer.
- Conditions
- Frailty, Delirium Confusional State, Persistent Critical Illness, Post-Intensive Care Syndrome
- Trial name
- LIFE-ICU (NCT07851974)
- Where
- 4 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Pain, Postoperative
Safety and Efficacy Study of Fentanyl Iontophoretic Transdermal System (ITS) for Management of Moderate to Severe Acute Pain in Participants Who Have Undergone Elective Spine or Orthopedic Surgery
The purpose of this study is to evaluate in daily clinical practice the safety and efficacy of fentanyl Iontophoretic Transdermal (through the skin) System (ITS) for management of moderate (medium level of seriousness) to severe…
- Trial name
- NCT00779038
- Testing
- Fentanyl ITS
- Where
- 3 sites in Belgium
- Volunteers
- 13 people
- Sponsor
- Janssen Cilag N.V./S.A.
Nutritional Deficiencies, Phenylketonuria
Follow-up of Adult Phenylketonuria (PKU) Patients
Adult patients with phenylketonuria (PKU) at the age around 40 years belong to the first patients generation with early treatment of the disease.
- Trial name
- NCT01096758
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich