Clinical trials: Neurological Outcome
Arthroplasty, Replacement, Knee
Silkeborg Knee Replacement Cohort Study
In this cohort study, we will investigate short and long term outcomes after knee replacement surgery and identify preoperative and early postoperative factors associated with long term outcome.
- Trial name
- NCT03411083
- Testing
- Total or unicompartmental knee replacement
- Where
- Denmark
- Volunteers
- 1,225 people
- Sponsor
- Central Jutland Regional Hospital
Anesthesia, Analgesia
Patient Reported Outcome After Bariatric Surgery
Prospective association study to analyse patients' outcome after bariatric surgery. Outcome comprises postoperative pain, analgesia, postoperative side-effects, long-lasting pain, patients' impairment in daily living.
- Conditions
- Anesthesia, Analgesia, Bariatric Surgery
- Trial name
- NCT03490630
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Brain Injury, Pupillary Reflex Impaired
Outcome pRognostication of Acute Brain Injury With the NeuroloGical Pupil indEx
The use of quantitative, automated, infrared technology for pupillary examination has long been used in ophthalmology and anesthesiology research.
- Trial name
- ORANGE (NCT04490005)
- Testing
- pupillometry
- Where
- 14 sites in United States, Belgium and 6 more
- Volunteers
- 118 people
- Sponsor
- University of Milano Bicocca
Pregnancy
Impact of Prenatal Yoga Practice on Birth Outcome
Yoga is a body-mind practice that encompasses a system of postures (asana), stretching exercises combined with breathing (pranayama) and meditation (dharana).
- Trial name
- NCT03941041
- Testing
- Prenatal Yoga Course
- Where
- Slovenia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Sarcopenia, COPD Exacerbation
The Impact of Sarcopenia on COPD Exacerbation Admission Outcome and Further Exacerbation Risk
Chronic obstructive pulmonary disease (COPD) is more prevalent and has more impact on health status because of progressive air pollution, tobacco smoking and aging society.
- Trial name
- NCT04885933
- Testing
- sarcopenia measurement
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Far Eastern Memorial Hospital
Mitral Valve Reconstruction
Neurologic Outcome After Mitral Valve Surgery
Reconstructive mitral valve surgery is increasingly done by minimal- invasive anterolateral thoracotomy technique in contrast to surgical approach by sternotomy.
- Trial name
- NCT03798015
- Testing
- mitral valve surgery
- Where
- Switzerland
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Ischemic, Sleep Disorder
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)
The study is aimed at the investigation of the association of biomarkers of circadian rhythms with sleep characteristics and stroke outcome in acute stroke patients.
- Trial name
- NCT05242393
- Testing
- No intervention is planned
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Pain, Postoperative, Pain
Virtual Reality and Pain
Determine the impact of VR-Biofeedback, VR-distraction, and 360 video on pain and medication utilization in patients undergoing surgery; determine the role of anxiety and pain catastrophizing on changes in pain following VR-BF in…
- Conditions
- Pain, Postoperative, Pain, Anxiety Postoperative
- Trial name
- FOREVR Peds (NCT04351776)
- Testing
- VR-Biofeedback, VR-Distraction, 360 Video
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Syncope, Arrhythmia
Mobile Cardiac Outpatient Telemetry for Unexplained Syncope
This study seeks to provide evidence that use of Philips mobile cardiac outpatient telemetry (MCOT) devices may improve patient care for patients who present to emergency departments (EDs) with syncope, which is a temporary loss…
- Conditions
- Syncope, Arrhythmia, Near Syncope, Arrhythmias, Cardiac
- Trial name
- NCT05957315
- Testing
- Mobile Cardiac Outpatient Telemetry Device (MCOT)
- Volunteers
- 160 people
- Sponsor
- Carilion Clinic
Communication Aids for Disabled, Communication Disorders
Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways
The study aims to improve the quality of prosthetic intervention and verify the adequacy of assistive devices, and measurement outcomes.
- Conditions
- Communication Aids for Disabled, Communication Disorders, Motor Disorders, Cognitive Disorder
- Trial name
- ATTAIN (NCT06546813)
- Testing
- scales and questionnaire administration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Failed Back Surgery Syndrome
Predicting Outcome of Transcutaneous Electrical Nerve Stimulator (TENS) in Failed Back Surgery Syndrome
The study investigates the feasibility and efficacy of Transcutaneous Electrical Nerve Stimulator (TENS) in a subgroup of patients with neuropathic pain.
- Trial name
- NCT01185665
- Testing
- TENS
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Reperfusion Syndrome
CRRT for Glutamate Elimination After Cardiac Arrest
Glutamate is known to be a mediator for apoptosis after brain hypoxia e.g. due to cardiac arrest. This pilot trial evaluates the possibility of elimination of Glutamate by CRRT after cardiac arrest.
- Trial name
- GCRRT (NCT02963298)
- Testing
- Continuous renal replacement therapy
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- C. Storm
Injuries, Musculoskeletal Pain
Translation and Psychometric Validation of an Italian Version of the Dance Functional Outcome Survey DFOS-IT
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Dance Functional Outcome Survey…
- Conditions
- Injuries, Musculoskeletal Pain, Low Back Pain, Lower Limb Injury
- Trial name
- DFOS-IT (NCT03918876)
- Where
- Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Angela Contri
Anoxic-Ischemic Encephalopathy
Study for the Improvement of Long-Term Outcome Prediction in Patients in Coma After Cardiac Arrest
The primary objective of HOPE is to improve the accuracy of outcome prediction in anoxic-ischemic encephalopathy following cardiac arrest by bringing under close scrutiny some of the existing methods used for this purpose (e.g.
- Trial name
- HOPE (NCT02231060)
- Where
- 16 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Hearing Loss
Coupler-Based Hearing-Aid Fitting Approach for Experienced Users
The overall aim of the study is to compare the verification accuracy and hearing-aid outcomes between the traditional, fitting approach where the patient is present during the visit and a coupler-based fitting approach where the…
- Trial name
- NCT02772757
- Testing
- standard hearing aid fitting, coupler-based fitting
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neonatal Seizures
Prophylactic Phenobarbital After Neonatal Seizures
The treatment of infants with medications after their seizures have stopped is very variable. No one knows if continuing treatment with phenobarbital for up to several months is helpful or harmful.
- Trial name
- PROPHENO (NCT01089504)
- Testing
- phenobarbital
- Where
- 18 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Rochester
Maternal Depression
Reducing Risk After an Adverse Pregnancy Outcome
This application to the Boston University Medical Center Institutional Review Board outlines a research plan devoted to identifying and managing maternal depression in Early Intervention (EI).
- Trial name
- NCT01182363
- Testing
- Project Solve Education
- Where
- 4 sites in United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Burns
A Randomized Comparison Study of Aquacel Ag and Glucan II as Donor Site Dressings
The research will be looking at patient outcomes for healing of donor sites after a split-thickness skin graft procedure for a burn or skin tissue loss.
- Trial name
- NCT00581217
- Testing
- Aquacel Ag, Glucan II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Spasticity, Muscle, Extracorporeal Shockwave Therapy
Early Radial Shock Waves Treatment on Spasticity in Patients With Stroke in Sub-acute Phase
Hands and wrist spasticity are a common post stroke complication and often lead to restrictions in daily living activities. Spasticity causes changes in muscle composition such as accumulation of collagenous connective tissue and…
- Conditions
- Spasticity, Muscle, Extracorporeal Shockwave Therapy, Rehabilitation
- Trial name
- NCT04365478
- Testing
- Radial Extracorporeal Shock Wave Therapy, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Stefano Brunelli
Acute Disease, Acute Hospitalization
Efficiency of the "Medidux" Smartphone App for Demission Management in Patients Medicated in Acute Admission Unit (AAU)
The goal of this clinical trial is to evaluate whether the use of the medidux™ smartphone app can optimize post-discharge management for patients admitted to Acute Admission Units (AAU) with non-urgent health complaints.
- Conditions
- Acute Disease, Acute Hospitalization, Coughing, Back Pain
- Trial name
- EffiDux (NCT06655337)
- Testing
- Smartphone Application for Post-Discharge Symptom Monitoring
- Where
- Switzerland
- Volunteers
- 417 people
- Sponsor
- Mobile Health AG