Clinical trials: Neurological Outcome
Phantom Limb Pain
Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.
Phantom limb pain (PLP), defined as pain felt in the missing portion of the amputated limb following amputation, occurs in a significant percentage of patients who undergo limb amputation and it is among the most difficult…
- Trial name
- NCT05005481
- Testing
- NIL intervention
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Tinnitus, Subjective, Sudden Deafness
The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
This clinical study is prospective, single-center, randomized, controlled, double-blind clinical trail, which entitled transcranial electrical stimulation for the treatment of acute tinnitus approved by Sun Yat-sen University…
- Conditions
- Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method
- Trial name
- NCT05964725
- Testing
- Receive traditional medical therapy and transcranial direct current stimulation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Parkinson Disease, Atypical Parkinsonism
Efficacy of Botulinum Toxin for the Treatment of Dystonia Associated With Parkinson's Disease and Atypical Parkinsonism
Dystonia is a disabling symptom affecting both patients with idiopathic Parkinson's disease (PD) and atypical parkinsonism (AP).
- Conditions
- Parkinson Disease, Atypical Parkinsonism, Dystonia
- Trial name
- NCT04948684
- Where
- France
- Volunteers
- 63 people
- Sponsor
- Hospital Avicenne
Muscle Atrophy, Myotonia
Electromyostimulation (EMS) of Astronauts in Spaceflight (Easymotion-2)
This is a prospective spaceflight study involving an investigational non-risk device called the EasyMotionSkin for whole body electric muscle (myo) stimulation (WB-EMS) onboard the International Space Station (ISS).
- Conditions
- Muscle Atrophy, Myotonia, Stiffness; Spine, Exercise Overtraining
- Trial name
- Easymotion-2 (NCT06492057)
- Testing
- Electromyostimulation (EMS), Myoton, Electromyography (EMG)
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Spinal Fusion
Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery
This is a prospective randomized, double-blinded, placebo-controlled, phase 2, 12-month pilot to study the efficacy of abaloparatide in postmenopausal women needing lumbar spinal fusion surgery.
- Trial name
- FAST-Healing (NCT03841058)
- Testing
- Abaloparatide
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Hospital for Special Surgery, New York
Hemorrhage; Intracerebral, Nontraumatic, Ischemic Strokes
Effect of Ischemic Strokes on Recovery From Intracerebral Hemorrhages
Intracerebral hemorrhage (ICH) occurs when small arteries in the brain rupture due to weakening by age, high blood pressure, and/or elevated cholesterol.
- Conditions
- Hemorrhage; Intracerebral, Nontraumatic, Ischemic Strokes, Diffusion Weighted Imaging Lesions
- Trial name
- NCT01417117
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Rush University Medical Center
Appendicitis, Postoperative Pain
Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block
This study is being conducted to compare two types of pain management techniques in patients undergoing open appendectomy (surgical removal of the appendix through a traditional incision).
- Trial name
- NCT06943456
- Testing
- Transversus Abdominis Plane (TAP) Block for Postoperative Pain Management, Standard Open Appendectomy with Postoperative Pain Management
- Volunteers
- 136 people
- Sponsor
- University of Health Sciences Lahore
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain, Disability
Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse
Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk…
- Conditions
- Pain, Disability, Paresis
- Trial name
- NCT00533286
- Testing
- benzodiacepine
- Sponsor
- University Hospital Tuebingen
Cardiac Arrest, Neurological Outcome
Early Neuroprognostication After OHCA
This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier…
- Conditions
- Cardiac Arrest, Neurological Outcome, EEG, CT
- Trial name
- NCT05706194
- Testing
- Early neurological prognostication with biomarkers, EEG and CT
- Where
- 4 sites in Finland, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Lund University
Cytomegalovirus Infections, Neurologic Dysfunction
Development of Potential Biomarkers for Foetal Brain Development After Congenital CMV Infection
Cytomegalovirus (CMV) is the most common cause of congenital infection, with approximately 0.5% of pregnant women being infected during pregnancy.
- Trial name
- NCT03188679
- Testing
- amniocentesis
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Disability Physical, Disability, Learning
AssessMent and Counseling to Get the Best Efficiency and Effectiveness of the Assistive TeCHnology
The best match between any person with disability and the assistive technology (AT) only can be gotten through a complete assessment and a monitoring of the needs, abilities, priorities, difficult and limitations that he/she…
- Conditions
- Disability Physical, Disability, Learning, Disabling Disease
- Trial name
- MATCH (NCT04723784)
- Testing
- Initial Assessment, Implementation of assistive technology in the daily life of participants, Application of outcome measures
- Where
- 4 sites in Spain
- Volunteers
- 24 people
- Sponsor
- Universidade da Coruña
Delirium
Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program
Delirium occurs in up to 20% of older adults presenting to the Emergency Department (ED) and is associated with poor outcomes. Failure to identify patients with ED delirium not only prevents initiation of mitigation strategies…
- Trial name
- ED-DDP (NCT05606328)
- Testing
- Emergency Department Delirium Screening and Detection Program (ED-DDP)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stroke, CVA (Cerebrovascular Accident)
Translation And Psychometric Testing Of The Turkish Version Of Fugl-Meyer Assessment
The aim of this methodological study is to adapt the Fugl-Meyer assessment to Turkish culture and to test its validity and reliability in acute phase stroke patients.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), Hemiplegia and/or Hemiparesis Following Stroke
- Trial name
- FMA-TR (NCT05823298)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Osteoarthritis, Chronic Pain
Preoperative Catastrophizing Predicts Pain Outcome After Shoulder, Knee and Hip Arthroplasty
Psychologic status is associated with poor outcome after joint arthroplasty and perhaps chronic pain. To enhance the therapeutic effect of a psychologic intervention, the specific disorders or pain-related beliefs that…
- Conditions
- Osteoarthritis, Chronic Pain, Catastrophization
- Trial name
- NCT02361359
- Testing
- Psychological questionnaires
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospital Ambroise Paré Paris
Conductive Hearing Loss, Tinnitus
Brain Mechanism and Outcome of Surgical Intervention of Conductive Hearing Loss.
This study explores the brain region activation and remodeling of poor connections of brain regions in the postoperative outcomes of conductive hearing loss patients with tinnitus by comparing pre - and post-operative…
- Conditions
- Conductive Hearing Loss, Tinnitus, Surgery
- Trial name
- NCT06535282
- Testing
- surgery
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stroke, Shoulder Injury
STRIPS: Shoulder Taping Reduces Injury and Pain in Stroke
Background and Rationale: The most commonly seen disabilities in stroke patients are shoulder injuries such as shoulder pain, glenohumeral subluxation, spasticity of shoulder muscles, soft-tissue trauma, rotator cuff tears, and…
- Trial name
- STRIPS (NCT01062308)
- Where
- 2 sites in India
- Volunteers
- 162 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Non ST Segment Elevation MI and Unstable Angina
Impact of Different Treatment in Multivessel Non ST Elevation Myocardial Infarction (NSTEMI) Patients: One Stage Versus Multistaged Percutaneous Coronary Intervention (PCI)
Patients with NSTEMI and multivessel disease will be scheduled to undergo early invasive strategy (PCI within 72 hours) of de novo native coronary artery lesions were considered for recruitment into the study.
- Trial name
- SMILE (NCT01478984)
- Testing
- One-Stage group, Multi-Staged group
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Gennaro Sardella
Presbycusis, Bilateral
Impact of Hearing Aid Technology on Self-reported Outcomes
The study aims to investigate if the level of hearing aid (HA) technology has an impact on self-reported outcomes in patients with presbycusis in terms of overall IOI-HA scores, Factor 1, Factor 2 scores, SSQ scores, and the SSQ…
- Trial name
- NCT04539847
- Testing
- High-end hearing aid, Basic hearing aid
- Volunteers
- 208 people
- Sponsor
- University of Southern Denmark