Clinical trials: Neurological Prognosis
Brain Injury, Coma, Cardiac Arrest (CA)
Prediction for Coma Recovery With Comaweb
The general objective of the comaScore project is to provide an external validation of the accuracy of the comaScore, a score derived from magnetic resonance imaging (MRI), to predict 1 year outcome of patients unresponsive to…
- Conditions
- Brain Injury, Coma, Cardiac Arrest (CA), Traumatic Brain Injury (TBI), Aneurysmal Subarachnoid Hemorrhages (aSAH)
- Trial name
- COMASCORE (NCT03874208)
- Testing
- MRI sequence, MRI
- Where
- France
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Status Epilepticus
Prognosis Factors Associated With Convulsive Status Epilepticus in Adults
The aim of the study is to evaluate, prospectively, prognosis factors associated with convulsive status epilepticus (CSE) in adults hospitalized in intensive care units.
- Trial name
- NCT00318578
- Where
- 34 sites in France
- Volunteers
- 100 people
- Sponsor
- Versailles Hospital
Vegetative State, Minimally Conscious State
Transcranial Brain Stimulation in Vegetative State Patients
The aim of this study is to determine whether transcranial brain stimulations, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are effective in terms of EEG…
- Trial name
- NCT01820923
- Testing
- Transcranial direct current stimulation (tDCS), Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Low Back Pain
Low Back Pain Among Care-seeking Families in General Practice
Background Low back pain (LBP) is the largest cause of years lived with disability worldwide and often associated with low quality of life, inability to work and low physical activity levels.
- Trial name
- NCT04148144
- Testing
- No intervention included
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University
Chest Pain
Prognosis of Very Low Dose SPECT
Nuclear stress testing evaluates whether the heart receives enough blood, by injection of a nuclear isotope during a stress on the heart that permits taking pictures of the heart muscle.
- Trial name
- NCT01387152
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Columbia University
Disorders of Consciousness Due to Severe Brain Injury
Peripheral Nerve Stimulation for Prognostic and Diagnostic Biomarker Identification in Disorders of Consciousness
This observational study aims to integrate anamnestic, clinical, and innovative neurophysiological data to assess their impact on the diagnosis and prognosis of patients with Disorders of Consciousness.
- Trial name
- MICRO-DOC (NCT06845800)
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD)
Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study
The study aims to provide initial proof-of-concept validation data of an artificial intelligence-based model to estimate individual Parkinson's disease risk using demographic, clinical, genetic information and digital biomarker…
- Conditions
- Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD), Neurogenic Orthostatic Hypotension, Hyposmia
- Trial name
- AI-PRA (NCT07706829)
- Testing
- Smartwatch and phone app
- Where
- 3 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Queen Mary University of London
Anoxic-Ischemic Encephalopathy
Study for the Improvement of Long-Term Outcome Prediction in Patients in Coma After Cardiac Arrest
The primary objective of HOPE is to improve the accuracy of outcome prediction in anoxic-ischemic encephalopathy following cardiac arrest by bringing under close scrutiny some of the existing methods used for this purpose (e.g.
- Trial name
- HOPE (NCT02231060)
- Where
- 16 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Lesional Coma
Imaging of the Neural Correlates of Arousal and Awareness
In last decades, several advances in the neuro-intensive management have lead to decrease mortality in Intensive Care Units. A significant morbidity remains as patients survive after a traumatic coma with uncertain quality of…
- Trial name
- IMAGINA (NCT04575454)
- Testing
- Multimodal evaluation of brain function : PET-MRI, electrophysiology, eye-tracking
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
TO FIND THE CORRELATION BETWEEN TINS SCORE OUTCOME
Trauma Infant Neurological Score (TINS) as a Prognostic Factor and Guideline for CT Scan in Infants 24 Months Old or Less
Traumatic brain injury (TBI) is the major cause of disability and death among the younger population. In the Pediatric population Head trauma may be responsible for primary and secondary brain damage.
- Trial name
- NCT02731781
- Testing
- NONE . OBSERVATIONAL
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Laniado Hospital
Head and Neck Cancer, Skeletal Muscle
Skeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients
This project adopts a prospective study design. It is scheduled to enroll 60 participants diagnosed with Head and Neck cancer in this hospital, of which 30 are in the experimental group and 30 are in the control group.
- Trial name
- NCT06666881
- Testing
- HIIT only, HIIT & Record of physical activities at home.
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- Chang Gung Memorial Hospital
Intracerebral Hemorrhage, Neurologic Deficits
Multicenter Registry for Assessment of Markers of Early Neurological Deterioration in Primary Intracerebral Hemorrhage
This multicenter observational study will explore the risk factors of early neurological deterioration(END) in patients with primary and to investigate the association between END and outcome.
- Conditions
- Intracerebral Hemorrhage, Neurologic Deficits, Hemorrhagic Stroke, Hemorrhage
- Trial name
- CATCH (NCT05502874)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chest Pain, Acute Aortic Dissection
Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital.
- Conditions
- Chest Pain, Acute Aortic Dissection, Pulmonary Embolism, Acute Myocardial Infarction Type 1
- Trial name
- PEACP (NCT04122573)
- Testing
- Coronary angiography, CT angiography of aorta, CT angiography of pulmonary arteries.
- Where
- 9 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Stroke, Acute, Stroke, Ischemic
Prognosis and Diagnosis of Spasticity in Acute-post Stroke Patients
Spasticity, or greater muscle resistance, is a major disabling condition following stroke. Recovery of lost motor function in patients with stroke may be affected by spasticity, which most commonly develops in elbow and ankle…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
- Trial name
- NCT05179473
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Spinal Cord Injury
Detection of Peripheral Blood Biomarkers in Intermediate Phase Spinal Cord Injury: Correlation With Neurological and Functional Outcomes, and Comparison to Other Central and Peripheral Neurological Conditions.
This research looks for markers in the blood of people with spinal cord injury that may be a sign of injury severity, or serve as a clue to the degree of recovery.
- Trial name
- NCT01516385
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Coronary Artery Disease, Angina Pectoris
Appropriateness of Angioplasty in Patients With Chronic Coronary Syndromes
Percutaneous coronary intervention (PCI) has dramatically changed the treatment of obstructive coronary artery disease patients.
- Trial name
- RIGHT-PCI (NCT06545448)
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- Brazil
- Volunteers
- 1,875 people
- Sponsor
- University of Sao Paulo General Hospital
Vestibular Vertigo, Sudden Hearing Loss
Vestibular Prognosis Assessment of ISSNHL With Vestibular Dysfunction Treated With Oral or Intratympanic Glucocorticoids
Idiopathic sudden sensorineural hearing loss (ISSNHL) is a complicated hearing impairment with unclear etiology and unsatisfying treatment effects.
- Trial name
- NCT03974867
- Testing
- Prednisone 5Mg Tab, Methylprednisolone 40 mg
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Out-Of-Hospital Cardiac Arrest
P25/30 SSEPs and Neurological Prognosis After Cardiac Arrest
Study Title: Early recorded P25/30 somatosensory evoked potentials are associated with neurologic prognosis of comatose survivors after out of hospital cardiac arrest.
- Trial name
- NCT03881865
- Where
- United Kingdom
- Volunteers
- 93 people
- Sponsor
- University Hospital Plymouth NHS Trust
Heart Valve Diseases, Image
Research on Neurological Prognosis of Patients Undergoing Heart Valve Surgery
The purpose of this study is to clarify the changes of neurocognitive function of patients undergoing cardiac valve disease before and after surgical treatment under cardiopulmonary bypass operation, and to predict the…
- Trial name
- NCT05539261
- Testing
- magnetic resonance image, Neuropsychological scale
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Bullous Pemphigoid
Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of 178 Patients
Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease
- Trial name
- NCT03320798
- Testing
- Data record
- Where
- France
- Volunteers
- 178 people
- Sponsor
- CHU de Reims