Clinical trials: Neuromodulation
Tinnitus, Subjective, Hyperacusis
Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy
The goal of this study is to use non-invasive transcranial direct current stimulation (tDCS) combined with active listening therapy to treat tinnitus and hyperacusis and related conditions.
- Conditions
- Tinnitus, Subjective, Hyperacusis, Hearing Disorders
- Trial name
- TDCS (NCT04934371)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arizona
Overactive Bladder
Evaluation of the The Neuromodulation System for the Treatment of Overactive Bladder Symptoms
To evaluate the efficacy and safety of non-invasive tibial nerve stimulator for the treatment of overactive bladder under the premise of ensuring the safety of the subjects and ensuring the scientific nature of the clinical…
- Trial name
- NCT04999657
- Testing
- Non-invasive low-frequency tibial nerve stimulator (TNS-01)
- Where
- 7 sites in China
- Volunteers
- 109 people
- Sponsor
- Medtecx Co Ltd.
Stroke
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03390192
- Testing
- Dual-mode stimulation
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Myofascial Pain Syndromes
Transcranial Magnetic Stimulation and/or Neurofunctional Electrical Acupuncture in Myofascial Chronic Pain Patients
To evaluate the hypothesis: the effects of repetitive transcranial magnetic (rTMS) stimulation and/or peripheral stimulation (neurofunctional electrical acupuncture) treatments are more effective in pain relief than placebo-sham…
- Trial name
- NCT02381171
- Testing
- Active rTMS, Active Neuroacupuncture
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Low-back Pain, Chronic Low-back Pain
Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain
Evaluate pain and disability change in Low Back Pain with DuoTherm Compared to Active Control
- Conditions
- Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
- Trial name
- NCT04494698
- Testing
- Duotherm VibraCool Back Device, TENS 8-channel unit
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Chronic Pain, Hemiplegic Shoulder Pain
StimRouter™ for Pain Management in Post-stroke Shoulder Pain
StimRouter Neuromodulation System includes an implanted lead which provides peripheral nerve stimulation for chronic pain. Post-stroke shoulder pain patients will be the focus of this study.
- Trial name
- PSSP (NCT03093935)
- Testing
- StimRouter Neuromodulation System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Bioness Inc
Faecal Incontinence, Faecal Incontinence With Faecal Urgency
Acs-Tens Treatment for Faecal Incontinence: a RCT With Sham-controls
This study assess the effectiveness on AcuTENS on the treatment of faecal incontinence
- Conditions
- Faecal Incontinence, Faecal Incontinence With Faecal Urgency, Neuromodulation, Transcutaneous Electric Nerve Stimulation
- Trial name
- NCT04749316
- Testing
- AcuTENS
- Where
- Hong Kong
- Volunteers
- 53 people
- Sponsor
- Chinese University of Hong Kong
Perinatal Spinal Cord Injury
Understanding Perinatal Spinal Cord Injury
The purpose of this study is to deepen our understanding of children who have a cervical spinal cord injury obtained in utero or at birth and examine the effects of tailored activity-based recovery training (ABRT) in combination…
- Trial name
- NCT06808035
- Testing
- Activity-Based Recovery Training, Transcutaneous Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Multiple Sclerosis
Neuromodulation in MS Using Translingual Stimulation
The overarching aim of this study is to examine if there is additional benefit to adding trans-lingual electrical stimulation to physiotherapy aimed at improving walking and balance in people with multiple sclerosis (MS).
- Trial name
- NeuroMSTraLS (NCT05275049)
- Testing
- PT plus translingual stimulation device, PT plus translingual stimulation control device
- Where
- 2 sites in Canada
- Volunteers
- 52 people
- Sponsor
- University of Saskatchewan
Overactive Bladder
PRospective Study to Evaluate EffectivenesS With the NURO™ PErcutaneous Tibial Neuromodulation System in Patients With OAB
To evaluate the NURO system for the treatment of OAB in drug naïve patients.
- Trial name
- RESET (NCT02857816)
- Testing
- NURO System PTNM Therapy
- Where
- 11 sites in United States
- Volunteers
- 154 people
- Sponsor
- MedtronicNeuro
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Anorexia Nervosa
Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation
Transcranial Magnetic Stimulation (TMS) is approved by the Food and Drug Administration (FDA) for the treatment of refractory Major Depressive Disorder (MDD) and obsessive-compulsive disorder (OCD).
- Trial name
- NCT06138782
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Overactive Bladder
Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder
This study is a retrospective chart review including all patients who received surgical placement of a SNM device with Dr. Noblett from 2001 to the present.
- Trial name
- NCT01047046
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Irvine
Complications; Neurostimulator, Satisfaction
Investigation of the Use of Remote Presence Robots in Delivery of Neuromodulation
In recent years, robotic devices are becoming more and more common in medical practice. Such devices provide an effective way to communicate within a clinical setting, but recent studies have shown far more diverse uses for these…
- Trial name
- NCT01283633
- Testing
- Neuromodulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Nova Scotia Health Authority
Spinal Cord Injury
Neuromodulation to Improve Grasping Function After SCI
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI.
- Trial name
- NCT07433959
- Testing
- iTBS, PCMS, Exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Essential Tremor
Cerebellar Research in Ultrasound Stimulation
Experiment 1: Modulation of Physiological Tremor in Healthy Volunteers Thirty healthy volunteers will undergo TUS targeting the dentate nucleus in a randomized, double-blinded crossover design.
- Trial name
- CERBERUS (NCT07508696)
- Testing
- Transcranial focused ultrasound delivered to the dentate nucleus using the NeuroFUS Pro by Brainbox, Transcranial focused ultrasound delivered to the ventricles (control) using the NeuroFUS Pro by Brainbox
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Herpes Zoster Pain
The Efficacy of High-frequency Short-time Spinal Cord Stimulation in the Treatment of Herpes Zoster-associated Neuralgia
Zoster-associated neuralgia (ZAN) is a type of neuropathic pain caused by the reactivation of the varicella-zoster virus (VZV). The global annual incidence is approximately 3-5 per 1,000 individuals, and in China, the incidence…
- Trial name
- NCT06942806
- Testing
- HF-SCS parameter settings: Frequency 1000 Hz, pulse width 60-180 μs, amplitude 0.5-3.0 V, LH-SCS parameter settings: Frequency 30-100 Hz, pulse width 100-300 μs, amplitude 0.5-5.0 V
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Li Zhao
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
Post-Amputation Pain, Phantom Limb Pain
Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System
The purpose of this study is to determine if electrical stimulation (small levels of electricity) can safely and effectively reduce post-amputation pain. This study involves a device called the SPRINT System.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain
- Trial name
- NCT01996254
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- SPR Therapeutics, Inc.
Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy
Effects of Adding Vagal Neuromodulation to Manual Therapy in Women With Fibromyalgia
The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients…
- Conditions
- Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy, Chronic Widespread Pain, Autonomic Nervous System Dysfunction
- Trial name
- NCT07894588
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Manual Therapy Program, Diaphragmatic Breathing and Stretching Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hasan Kalyoncu University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.