Clinical trials: Neuromodulation
Overactive Bladder
Evaluation of the The Neuromodulation System for the Treatment of Overactive Bladder Symptoms
To evaluate the efficacy and safety of non-invasive tibial nerve stimulator for the treatment of overactive bladder under the premise of ensuring the safety of the subjects and ensuring the scientific nature of the clinical…
- Trial name
- NCT04999657
- Testing
- Non-invasive low-frequency tibial nerve stimulator (TNS-01)
- Where
- 7 sites in China
- Volunteers
- 109 people
- Sponsor
- Medtecx Co Ltd.
Acute Low-back Pain, Chronic Low-back Pain
Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain
Evaluate pain and disability change in Low Back Pain with DuoTherm Compared to Active Control
- Conditions
- Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
- Trial name
- NCT04494698
- Testing
- Duotherm VibraCool Back Device, TENS 8-channel unit
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Chronic Pain, Hemiplegic Shoulder Pain
StimRouter™ for Pain Management in Post-stroke Shoulder Pain
StimRouter Neuromodulation System includes an implanted lead which provides peripheral nerve stimulation for chronic pain. Post-stroke shoulder pain patients will be the focus of this study.
- Trial name
- PSSP (NCT03093935)
- Testing
- StimRouter Neuromodulation System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Bioness Inc
Overactive Bladder
PRospective Study to Evaluate EffectivenesS With the NURO™ PErcutaneous Tibial Neuromodulation System in Patients With OAB
To evaluate the NURO system for the treatment of OAB in drug naïve patients.
- Trial name
- RESET (NCT02857816)
- Testing
- NURO System PTNM Therapy
- Where
- 11 sites in United States
- Volunteers
- 154 people
- Sponsor
- MedtronicNeuro
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
Post-Amputation Pain, Phantom Limb Pain
Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System
The purpose of this study is to determine if electrical stimulation (small levels of electricity) can safely and effectively reduce post-amputation pain. This study involves a device called the SPRINT System.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain
- Trial name
- NCT01996254
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- SPR Therapeutics, Inc.
Urinary Incontinence, Urge
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system.
- Trial name
- PROTECT (NCT02577302)
- Testing
- CAN-Stim - Protect CAN-Stim System, SNS - InterStim® System
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- Uro Medical Corporation
Migraine
Real World Data Analysis: Impact of High-Frequency REN Treatments As Migraine Preventive Therapy in Adolescence
This is a post-marketing study investigating the safety and efficacy of the REN device (Nerivio by Theranica, ISRAEL) in adolescents with migraine.
- Trial name
- NCT05769322
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Theranica
Postpartum Depression (PPD)
SAINT in Postpartum Depression (PPD)
This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively…
- Trial name
- NCT07210255
- Testing
- SAINT Neuromodulation System
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Magnus Medical
Migraine, Acute Treatment of Migraine
Nerivio Long-term Usage in Patients With Migraine
This is a post-marketing real-world evidence study investigates long-term treatment with the Remote Electrical Neuromodulation (REN) wearable Nerivio device over 3 consecutive years in patients with migraine.
- Trial name
- NCT06738056
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 244 people
- Sponsor
- Theranica
Urinary Bladder, Overactive
FemPulse Therapy for Overactive Bladder in Women
The purpose of this clinical trial is to investigate a new medical device treatment for Overactive Bladder (OAB) in women.
- Trial name
- EVANESCE-OAB (NCT03784170)
- Testing
- FemPulse System
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- FemPulse Corporation
Urinary Incontinence
An Implantable Microstimulator for the Chronic Treatment of Refractory Urinary Urge Incontinence
This clinical trial is being conducted to investigate the safety and effectiveness of a new device designed to treat urinary urge incontinence in those patients who have tried and failed two or more conservative therapies.
- Trial name
- NCT00080470
- Testing
- bion
- Where
- 11 sites in United States
- Volunteers
- 148 people
- Sponsor
- Boston Scientific Corporation
Dry Eye Syndromes
A Usability Study of External Neuromodulation With iTEAR100 Generation 2
A Usability Study of External Neuromodulation With iTEAR100 Generation 2. A study which evaluates user ability to train and access the iTEAR100 device in a telehealth environment.
- Trial name
- NCT05304650
- Testing
- iTEAR100
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Olympic Ophthalmics, Inc.
Migraine Headache, Episodic
A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache
This is a randomized, blinded study designed to assess the efficacy of a portable, non-invasive neuromodulation system for the treatment of episodic migraine headaches.
- Trial name
- NCT01899040
- Testing
- neuromodulation for episodic migraine headache
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Scion NeuroStim
Mild Alzheimer's Disease
WeArable Neuromodulation DeVice for the TrEatment of Alzheimer's Disease
This is a double- blind, randomized controlled trial with an open label extension designed to evaluate the safety and potential efficacy of a non-invasive brainstem neuromodulation device for treating symptoms associated with…
- Trial name
- WAVE-AD (NCT05032482)
- Testing
- Non-invasive brainstem stimulation
- Where
- 5 sites in United States
- Sponsor
- Scion NeuroStim
Cervical Spinal Cord Injury
ExaStim Upper Limb Home Use Clinical Validation Study
This is a multi-center, observational, single-arm, 6-week home study to evaluate the safety and efficacy of transcutaneous spinal cord stimulation via the ExaStim system for 4 consecutive weeks used in the home setting for…
- Trial name
- NCT06850363
- Testing
- ExaStim Stimulation System
- Where
- 5 sites in United States
- Volunteers
- 33 people
- Sponsor
- Niche Biomedical, Inc. dba ANEUVO
Migraine
Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study
Preventive pharmacologic therapies for migraine aim to reduce attack frequency and duration and improve quality of life; however, their use, overall benefit and adherence are often limited.
- Trial name
- NCT07487701
- Testing
- Nerivio REN device
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
Tinnitus, Subjective, Tinnitus, Bilateral
Tinnitus Patient Preferences Survey
The goal of this survey is to assess several aspects related to patient preferences regarding interventions for alleviating tinnitus through invasive electrical brain stimulation (neuromodulation).
- Conditions
- Tinnitus, Subjective, Tinnitus, Bilateral, Tinnitus, Noise Induced, Tinnitus, Hearing Loss, Cochlear Implant Users
- Trial name
- NCT06782308
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Nicolas Gninenko
Urinary Bladder, Overactive
FemPulse Therapy First-in-Human Experience
The purpose of this clinical trial is to investigate a new medical device treatment for Overactive Bladder (OAB) in women.
- Trial name
- NCT03874637
- Testing
- Treament
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- FemPulse Corporation
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC