Clinical trials: Neuromuscular Blockade
Bariatric Surgery
Determinants on Rocuronium Dose for Deep Block in Bariatric Surgery
Find out the deciding factor(total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) of neuromuscular blocker dose for deep neuromuscular blockade in bariatric…
- Trial name
- NCT04709406
- Testing
- deep neuromuscular blockade in bariatric surgery
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Neuromuscular Blockade
Neuromuscular Monitoring:TOFCuff Versus EMG
Mechanomyography (MMG) is considered the gold-standard for neuromuscular blockade (NMB) monitoring. However, it is quite bulky and difficult to use on a routine basis.
- Trial name
- NCT04282213
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Servei Central d'Anestesiologia
General Anesthesia, Elective Surgery
Effect of Pre-injection of Rocuronium on Neuromuscular Blockade Onset Time and Hemodynamics During General Anesthesia Induction
This is a single-center, prospective, randomized, controlled trial comparing pre-injection versus standard bolus administration of rocuronium bromide for general anesthesia induction.
- Trial name
- NCT07716891
- Testing
- Rocuronium Bromide (Pretreatment Injection), Rocuronium Bromide (Conventional Injection)
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Neuromuscular Blockade
Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)
A multi-center, randomized, parallel group, comparative, active controlled, safety assessor blinded trial in adult subjects comparing rocuronium plus sugammadex versus succinylcholine alone in subjects undergoing short surgical…
- Trial name
- NCT00751179
- Testing
- rocuronium, sugammadex, succinylcholine
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Neuromuscular Blockade, Neuromuscular Monitoring
A Comparison Between TOF Watch® SX and Tetragraph®
This observational study was designed to assess the agreement between the recently marketed electromyographic neuromuscular blockade monitor Tetragraph® (Senzime, Uppsala, Sweden) and the TOF Watch® SX (Organon Teknika B.V.…
- Trial name
- NCT04947306
- Testing
- Tetragraph® (Senzime, Uppsala, Sweden), TOF Watch® SX (Organon Teknika B.V., Boxtel, Holland)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Caregiver Burden, Dementia
Progressive Muscle Relaxation Exercise on Care Burden, Depression, Anxiety, and Stress Levels in Dementia Caregivers
Dementia, which leads to deterioration in cognitive and behavioral functions, is a chronic progressive disease. Since the diagnosis is made, the care needs of the patients increase.
- Trial name
- NCT06143826
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Cardiovascular Complication
Effect of DASH Diet and Progressive Muscle Relaxation on Cardiovascular Risks in Postmenopausal Women
This study will be conducted to investigate the effect of DASH diet and Progressive muscle relaxation on cardiovascular risks in postmenopausal women.
- Trial name
- NCT06600347
- Testing
- DASH diet, Progressive muscle relaxation, Anti hypertensive drugs
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia
Relationship Between Muscle Mass and Muscle Relaxation Time
Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of…
- Trial name
- NCT02617433
- Testing
- Inbody
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Go Eun Bae
Respiratory Muscles, Electromyography
Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade
It was recently shown that neostigmine reversal was associated with increased atelectasis and that high-dose neostigmine was associated with longer postoperative length of stay and with an increased incidence of pulmonary edema…
- Trial name
- REDNESII (NCT02403063)
- Testing
- Sugammadex, Neostigmine, Neostigmine-sugammadex
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouw Hospital
Colorectal Cancer
The Benefits of Deep Neuromuscular Block and Sugammadex in Laparoscopic Colorectal Surgery
Pneumoperitoneum, the use of carbon dioxide, presents some disadvantages, including a risk of hypercarbia and respiratory acidosis during surgery in the respiratory system, and of an increased mean arterial pressure and systemic…
- Trial name
- NCT02266056
- Testing
- Deep neuromuscular block using rocuronium and reversal with suggamadex, Moderate neuromuscular block using rocuronium and reversal with suggamadex
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Low Back Pain
A Prospective Pilot Study Investigating the Impact of ThermaCare on Flexibility, Muscle Relaxation & Low Back Pain
The objective of this Investigator Initiated study is to evaluate the effectiveness of ThermaCare HeatWraps in improving flexibility and low back muscle relaxation, and in participants experiencing pain, reducing pain during…
- Trial name
- NCT03151265
- Testing
- ThermaCare Low Back Heat Wrap
- Where
- 3 sites in Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- dorsaVi Ltd
Neuromuscular Blockade
Low Dose of Sugammadex vs Neostigmine and Glycopyrrolate for the Reversal of Rocuronium
The aim of this study is to compare the use of a low dose sugammadex and neostigmine combined to glycopyrrolate to reverse a rocuronium induced moderate neuromuscular blockade.
- Trial name
- SUGANEO (NCT05718934)
- Testing
- Neostigmine and glycopyrrolate, Sugammadex
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Women With Low Sexual Satisfaction, Partners of Women With Low Sexual Satisfaction
Progressive Muscle Relaxation Exercises Women With Low Sexual Satisfaction Sexual Satisfaction and Functioning of Women and Their Partners
This study was conducted to investigate the effect of progressive muscle relaxation exercises on sexual satisfaction and functioning of women and their partners in women with low sexual satisfaction.
- Trial name
- NCT06354283
- Testing
- Progressive Muscle Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Halic University
Drop Foot
The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care
This pilot study aims to investigate the effects of nerve blocks in patients with diabetic peripheral neuropathy through a double-blinded, randomized trial involving 4 patients.
- Trial name
- NCT06919289
- Testing
- Infiltration of papaverine, Lidocaine infiltration
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Neuropathy Centers
Head and Neck Cancer
Magnesium Sulphate and Rocuronium in Patients Over 60
The purpose of this study is to evaluate the effects of MgSO4 administration on the pharmacodynamics of rocuronium in patients with 60 or more years of age.
- Trial name
- NCT01804205
- Testing
- Magnesium Sulfate
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pedro Rotava
Pregnancy
Comparison of Onset and Duration of Rocuronium Between 2nd Trimester Pregnant and Non-pregnant Women
Pregnancy is associated with major changes of the body's physiological status and composition. These changes may modify the pharmacologic and/or pharmacokinetic profile of some drugs.
- Trial name
- NCT02797860
- Testing
- Rocuronium
- Where
- South Korea
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Anxiety, Stress
The Effect of Web Based Progressive Muscle Relaxation Exercise on Clinical Stress and Anxiety of Nursing Students
Purpose: The study was conducted to examine the effect of web-based progressive muscle relaxation exercise on the perceived stress and anxiety level of nursing students who were in clinical practice for the first time.
- Conditions
- Anxiety, Stress, Nursing Students, Relaxation Program
- Trial name
- NCT05312749
- Testing
- progressive relaxation exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Restless Legs Syndrome
The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndrome
Restless Leg Syndrome (RLS) is a sensory-motor problem characterized by an uncomfortable and unpleasant feeling that causes a strong and overwhelming desire to move the legs, usually during periods of inactivity during sleep.It…
- Trial name
- NCT04853771
- Testing
- progressive muscle relaxation exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Nerve Pain
A Comparison Between Posterior, Lateral and Medial Approaches for Ultrasound-guided Popliteal Block
Background: Popliteal block is a widely used technique to provide anesthesia or analgesia for below-knee surgical procedures. In this study, the investigators compare ultrasound-guided popliteal blocks via posterior, lateral, and…
- Trial name
- NCT06489210
- Testing
- popliteal block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Helwan University
Pain
Double-blind Trial of Mannitol Cream to Block the Effect of Capsaicin Cream
Capsaicin is a TRPV1 (transient receptor potential vanilloid 1) agonist, causing pain upon application. The investigators wish to determine whether mannitol blocks the effect of capsaicin application.
- Trial name
- LipTRP (NCT01963910)
- Testing
- 30% Mannitol in vehicle cream, vehicle cream
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia