Clinical trials: Neuromuscular Disease Patients
Osteoarthritis, Pain Intensity Assessment
A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
The purpose of this study is to evaluate the safety of CG5503 base Immediate Release(IR) 50 mg or 100 mg taken every 4 to 6 hours as needed over the long-term exposure of 90 days in patients who have chronic pain.
- Conditions
- Osteoarthritis, Pain Intensity Assessment, Arthralgia, Sciatica
- Trial name
- NCT00364546
- Testing
- CG 5503;tapentadol
- Volunteers
- 877 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
Muscle and Bone in Patients with Diabetes Mellitus and Neuropathy
The goal of this observational study is to evaluate muscle fiber type composition in people with type 2 diabetes mellitus (T2DM) with a common complication of T2DM: diabetic peripheral neuropathy (DNP), specifically diabetic…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy, Sarcopenia
- Trial name
- SVT-DNP (NCT06519942)
- Testing
- Blood sampling, Electromyoneurography (EMNG), Muscle biopsy
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Carpal Tunnel Syndrome (CTS)
Effect of Neural Mobilization on Carpal Tunnel Syndrome
The study group (G1) consisted of 15 patients treated by neural mobilization techniques targeting the median nerve, in addition to a selected physical therapy program including transcutaneous electrical nerve stimulation (TENS)…
- Trial name
- CTS (NCT07779096)
- Testing
- Neuromobilization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Vitamin D Deficiency, Sarcopenia
Vitamin D Deficiency and Body Composition in the Patients With Hemophilia
Hemophilia is associated with osteoporosis and increased prevalence of low bone mineral density (BMD). Many clinical risk factors have been reported, such as hemophilic arthropathy, reduced physical activity, decreased sun…
- Conditions
- Vitamin D Deficiency, Sarcopenia, Osteoporosis, Body Composition
- Trial name
- NCT05517070
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tsung-Ying Li
Carpal Tunnel Syndrome (CTS), Peloidotherapy
Efficacy of Paraffin Bath and Peloidotherapy in Carpal Tunnel Syndrome
Patients diagnosed with mild and moderate idiopathic CTS will be randomly divided into three groups. Patients who received 15 sessions of peloid therapy along with a home exercise program will constitute the first group.
- Conditions
- Carpal Tunnel Syndrome (CTS), Peloidotherapy, Paraffin Bath, Exercise
- Trial name
- NCT06986668
- Testing
- Peloidotherapy, paraffin bath, home exersize
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Idiopathic Pulmonary Fibrosis, Neuromuscular Electrical Stimulation
Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis
Pulmonary rehabilitation should be initiated and lifelong at the time of diagnosis for patients with IPF. However, the symptoms of the disease and its progression limit clinical options in terms of participation and…
- Trial name
- NCT03890250
- Testing
- Aerobic exercise, Neuromuscular electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Biruni University
Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy < 18y in Norway: Genotype/Phenotype, Growth, Puberty, Bone Health and Quality of Life.
The study will give a consent based epidemiological overview of Norwegian patients with Duchenne muscular dystrophy younger than 18 years of age. Genotype of the population will be described.
- Trial name
- NCT01963897
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Oslo University Hospital
Myasthenia Gravis, Generalized
A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE)
The purpose of this Phase 3 study is to demonstrate the efficacy, safety, and tolerability of claseprubart in participants with generalized myasthenia gravis (gMG).
- Trial name
- NCT07647510
- Testing
- Claseprubart
- Where
- 12 sites in United States, Georgia and 1 more
- Volunteers
- 195 people
- Sponsor
- Dianthus Therapeutics
Muscular Atrophy, Spinal, Ultrasound
Ultrasound-assisted vs Landmark Based Intrathecal Administration of Nusinersen
Intrathecal administration of Nusinersen, an antisense oligonucleotide capable of increasing Survival Motor Neuron protein production, has been tested in Spinal Muscular Atrophy (SMA) to improve motor function and survival.
- Trial name
- NCT04674618
- Testing
- US-assisted nusinersen administration
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Carpal Tunnel Syndrome
Evaluation of the Acute Effect of Kinesio Taping by Ultrasonography
The design of our study is a randomized, controlled, double-blind study. It is planned to be completed in twenty-four weeks with 34 participants.
- Trial name
- NCT05475197
- Testing
- Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Mersin University
Morton's Neuroma
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine)
To characterize the phenotype in patients with Morton's neuroma and to explore the effect of local administration of Xylocaine (lidocaine)
- Trial name
- NCT01298310
- Testing
- Xylocaine
- Where
- Sweden
- Volunteers
- 27 people
- Sponsor
- AstraZeneca
Fibromyalgia, Ankylosing Spondylitis
Frequency of Axial Spondyloarthropathy Among Patients Suffering From Fibromyalgia
Fibromyalgia Syndrome (FMS) is a non - inflammatory condition characterized by the presence of chronic, widespread musculoskeletal pain and tenderness; FMS is considered to be the result of increased processing of pain by the…
- Trial name
- NCT01167413
- Testing
- Evaluation by manual Dolorimeter, SIJ imaging
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Trismus, Radiation-induced Fibrosis
Physiotherapy for Radiation-induced Trismus
The purpose of this study is to assess the effect of two protocols of physiotherapeutic exercises in the maintenance and/or increase of the mandibular range of movement in patients suffering from head and neck cancer (HNC) who…
- Trial name
- NCT02094690
- Testing
- Therabite, Hyperboloid
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Cancer
Study to Determine if the Flu Vaccine Increases the Risk of Muscle Damage in Participants Taking Drugs That Block Certain Proteins Made by Some Types of Immune System Cells
A retrospective, observational study conducted on cancer patients receiving a drug that blocks certain proteins made by some types of immune system cells
- Trial name
- NCT03644498
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 1,056 people
- Sponsor
- Bristol-Myers Squibb
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Duchenne Muscular Dystrophy
Transplantation of Myoblasts to Duchenne Muscular Dystrophy (DMD) Patients
This Phase I/II of the clinical trial is to investigate whether the transplantation of normal myoblasts throughout one muscle (the extensor carpi radialis) of the patients is safe and will improve the strength of that muscle.
- Trial name
- NCT02196467
- Testing
- Myoblast transplantation, Saline injection
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- CHU de Quebec-Universite Laval
Fibromyalgia, Irritable Bowel Syndrome
Exercise, Irritable Bowel Syndrome and Fibromyalgia
The project focuses on "somatic functional syndrome", a category of disorders characterized by subjective symptoms, suffering and disability without evident organic or functional alterations.
- Trial name
- AF-IBS-FM (NCT06166563)
- Testing
- Exercise Program
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Cervical Radiculopathy
Effects of DRT on Neck Pain, ROM, and Chest Expansion in Patients With CR
This randomized controlled trial aims to determine the effects of the diaphragmatic release technique on neck pain, cervical range of motion, and chest expansion in patients with cervical radiculopathy.
- Trial name
- NCT07628348
- Testing
- Diaphragmatic Release Technique, Traditional Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Critical Illness, Muscle Wasting
Acute Skeletal Muscle Wasting and Relation to Physical Function in Patients Requiring ECMO
The purpose of this study is to describe the changes in quadriceps muscle size and quality over the first 10 days on extracorporeal membrane oxygenation (ECMO) using ultrasound imaging.
- Conditions
- Critical Illness, Muscle Wasting, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03026985
- Testing
- Observational cohort
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- The Alfred
Becker Muscular Dystrophy
Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients With Becker Muscular Dystrophy
Objectives: Primary objective: to establish the histological effects of Givinostat versus placebo administered over 12 months. Secondary Objectives: To establish the macroscopic muscle effects of Givinostat versus placebo…
- Trial name
- NCT03238235
- Testing
- Givinostat
- Where
- 2 sites in Italy, Netherlands
- Volunteers
- 51 people
- Sponsor
- Italfarmaco
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.