Clinical trials: Neuromuscular Disease Patients
Amyotrophic Lateral Sclerosis
Home Care Needs and Current Nursing Status of Patients With Amyotrophic Lateral Sclerosis
The purpose of this study is to comprehensively investigate and analyze the home care needs and status quo of ALS patients in China, and to clarify their home care needs and status quo, so as to provide reference for the…
- Trial name
- NCT04953481
- Testing
- survey
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Peking University Third Hospital
Familial Dysautonomia
The Safety and Tolerability of Kinetin, in Patients With Familial Dysautonomia
This is a study of kinetin, a nutritional supplement that corrects the mRNA splicing defect in patients with familial dysautonomia (FD, also known as Riley Day syndrome or hereditary sensory and autonomic neuropathy type III).
- Trial name
- NCT02274051
- Testing
- Kinetin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Osteoporotic Fracture of Femur, Osteoarthritis, Hip
Study of Parameters of Osteosarcopenia in Patients With Hip Fracture
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck.
- Trial name
- NCT04730622
- Testing
- SARC-F questionnaire, Bone tissue histology, Muscle tissue histology
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Muscle Wasting
Effects of Omega-3 Fatty Acids on Muscle Wasting
The risk of muscle wasting, and sarcopenia is high in the intensive care unit patients and associated with adverse clinical outcomes.
- Trial name
- NCT04582630
- Testing
- omega 3 fatty acid
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Karadeniz Technical University
Myasthenia Gravis
Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of Immune Globulin (Human), 10% Caprylate/Chromatography Purified (IGIV-C) as a corticosteroid (CS)-sparing agent in…
- Trial name
- NCT02473965
- Testing
- IGIV-C
- Where
- 39 sites in United States, Belgium and 8 more
- Volunteers
- 60 people
- Sponsor
- Grifols Therapeutics LLC
Chronic Pain, Carpal Tunnel Syndrome
Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modaleties are available for treatment of mild to moderate CTS.
- Trial name
- NCT04961281
- Testing
- Dexmedetomidine, Triamcinolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Peripheral Neuropathies
Synergic Control of Posture in Peripheral Neuropathies' Patients
This is a multicenter observational study aimed to characterize multi-muscle synergy organization in relation to postural stability in individuals with Peripheral Neuropathies (PN) compared to healthy age-matched subjects and to…
- Trial name
- NEUPER (NCT05088681)
- Testing
- Rehabilitation program
- Where
- 2 sites in Italy
- Volunteers
- 26 people
- Sponsor
- University of Milano Bicocca
Acute Coronary Syndromes (ACS), Cardiac Rehabilitation
Patient-centered Personalized Cardiac Rehabilitation in Post Acute Coronary Syndrome (BREAK-trial)
The primary objective of this study is to compare an integrated, multidisciplinar patient-centered CRP (Cardiac Rehabilitation Program) (intervention group) especially focused on covering the needs for the female and fragile…
- Conditions
- Acute Coronary Syndromes (ACS), Cardiac Rehabilitation, Frailty, Women
- Trial name
- BREAK (NCT07038265)
- Testing
- Personalised treatment, Usual Care
- Where
- Spain
- Volunteers
- 202 people
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
ALS, Motor Neuron Disease
Deep Phenotyping in Patients With ALS
This study aims to establish a biorepository and phenotyping database to investigate longitudinal changes in ALS subjects. Blood, including DNA and RNA, cerebrospinal fluid (CSF) and electrophysiologic measures will be collected…
- Trial name
- NCT02819765
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- Barrow Neurological Institute
Fibromyalgia
Body Awareness Therapy and Biomarkers in Fibromyalgia
A randomized trial of Basic Body Awareness Therapy (BBAT) is applied in fibromyalgia patients as compared with a control intervention consisting of stretching.
- Trial name
- BATBF (NCT05555394)
- Testing
- Basic Body Awareness Therapy, Stretching Exercise
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Universitat de Lleida
Cancer, Pain
Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
The aim of the study is to assess tolerability and activity of oxycodone and pregabalin in combination for the treatment of oncological neuropathic pain with two different strategies.
- Trial name
- NCT00637975
- Testing
- oxycodone, pregabalin
- Where
- 8 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Associazione Progetto Oncologia UMAN.A
Fibromyalgia
Randomized, Double-Blind, Placebo-Controlled Trial Of Pregabalin In Patients With Fibromyalgia.
This study, will compare pregabalin with placebo for the duration of 14 weeks to evaluate the efficacy and safety of pregabalin in patients with fibromyalgia.
- Trial name
- NCT00333866
- Testing
- pregabalin
- Where
- 74 sites in Australia, Canada and 14 more
- Volunteers
- 747 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Carpal Tunnel Syndrome
Sonographic Evaluation of Patients With Carpal Tunnel Syndrome Following Steroid Injection
The objective of this study was to assess sonographic changes of the median nerve after steroid injection for carpal tunnel syndrome.
- Trial name
- NCT03132051
- Testing
- steroid injection
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Fibromyalgia, Manual Therapy
Effects of Manual Therapy on Autonomic Nervous System's Balance, Pain and Well-being in Patients With Fibromyalgia.
Scientific literature dealing with patients with fibromyalgia conveys they suffer from an abnormal response of the autonomic nervous sýstem, where a marked sympathetic hyperactivity and a decrease in heart rate variability are…
- Trial name
- NCT03740451
- Testing
- Active mobilization of soft tissues, Passive mobilization
- Volunteers
- 50 people
- Sponsor
- Universidad Francisco de Vitoria
Familial Amyloid Neuropathy, Transthyretin Amyloidosis
Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology
Familial amyloid neuropathy due to transthyretin gene mutations (TTR-FAP) is a rare autosomal dominant inherited disease resulting in the abnormal multi-system deposition of amyloid proteins.
- Trial name
- PRE-TRANS (NCT03190577)
- Testing
- blood sample
- Where
- 12 sites in France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Breast Cancer, Neuropathy;Peripheral
Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy
Taxol is a very effective drug in breast cancer, but it can cause peripheral neuropathy (PN). This toxicity is often dose-limiting.
- Trial name
- NCT06422949
- Testing
- Hilotherm® Cooling treatment
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
Muscle Spasticity
Observational Study of Botox® Treatment for Patients With Upper Limb Adult Spasticity
This is a prospective, non-interventional, observational study to collect data on the use of botulinum toxin Type A in a routine setting in patients with upper limb adult spasticity.
- Trial name
- NCT01387074
- Testing
- botulinum toxin Type A
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Allergan
Sarcopenia, Cirrhosis
Muscle Mass Via UltraSound in Cirrhosis (MMUSCLE)
The goal of this observational cohort study is to learn about loss of muscle mass and muscle strength (sarcopenia) in patients with cirrhosis.
- Conditions
- Sarcopenia, Cirrhosis, Malnutrition
- Trial name
- MMUSCLE (NCT06345547)
- Testing
- ultrasound
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Antwerp
Carpal Tunnel Syndrome (CTS), Fascial Mobilization
Effects of Fascial Mobilization Therapy in Patients With Carpal Tunnel Syndrome
The aim of this study, designed as a randomized controlled trial, is to investigate the effects of fascial mobilization treatment on pain, grip strength, and manual dexterity in patients with postpartum carpal tunnel syndrome.
- Conditions
- Carpal Tunnel Syndrome (CTS), Fascial Mobilization, Post Partum
- Trial name
- NCT07233343
- Testing
- Conventional physiotherapy, Fascial mobilization therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Non-small Cell Lung Cancer (NSCLC), Small Cell Lung Cancer (SCLC)
Sarcopenia and Cachexia in Patients With Lung Cancer
The PHILICA study investigates whether muscle mass, muscle strength, and muscle function are associated with treatment tolerance, quality of life and survival in patients with lung cancer.
- Trial name
- PHILUCA (NCT06730685)
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Zealand University Hospital
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