Clinical trials: Neuromuscular Disease Patients
Diabetic Peripheral Neuropathy, Neuralgia
A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy
This is a multicenter, randomized, placebo-controlled, parallel group study of EpiCept™ NP-1 Topical Cream (amitriptyline 4%/ketamine 2%) in approximately 200 patients with pain in the lower extremities due to diabetic nerve pain.
- Trial name
- NCT00476151
- Testing
- EpiCept NP-1 (4% Amitriptyline/ 2% Ketamine) Topical Cream
- Where
- India
- Volunteers
- 226 people
- Sponsor
- EpiCept Corporation
Neuralgia
To Evaluate the Efficacy and Tolerability of the Use of Vitatonus Dexa Compared to Dexamethasone in Patients With Neuralgia of Various Origins
To evaluate the efficacy and tolerability of Vitatonus Dexa compared with dexamethasone in the signs and symptoms of neuralgia of various origins.
- Trial name
- NCT00944502
- Testing
- Dexamethasone
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Bunker Industria Farmaceutica Ltda.
Diabetic Neuropathies, Mobility
Effects of Modified Otago Versus Action Observation on Strength, Mobility and Fall Risk in Diabetic Neuropathy
To compare the Effects of Modified Otago Exercise and Action Observation Training on strength, functional mobility and fall risk in patients with diabetic neuropathy.
- Conditions
- Diabetic Neuropathies, Mobility, Fall
- Trial name
- NCT06459375
- Testing
- modified otago exercises, Action Observation Training
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Peripheral Neuropathy in Breast Cancer Patient
Nutraceuticals Versus Usual Care in the Prevention or Reduction of CIPN in Patients Treated With Docetaxel as Neoadjuvant/Adjuvant Breast Cancer Therapy
The trial will utilize Nutraceuticals (Vitamin D 2000IU oral once daily, Vitamin B6 100 mg oral once daily, Vitamin B12 100 mcg oral once daily, Omega-3 Fatty Acids 900 mg oral three times a day) in patients treated with…
- Trial name
- CIPN (NCT02795572)
- Testing
- Vitamin D, Vitamin B6, Vitamin B12
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- AHS Cancer Control Alberta
Stroke, Motor Disorders
Functional Proprioceptive Stimulation of the Upper Limbs in Stroke Patients
Parallel-group, single-blinded controlled clinical trial. The study involved stroke patients (no more than 3 points on a scale Rankin) dived of the control group and experimental group.
- Conditions
- Stroke, Motor Disorders, Upper Extremity Paresis, Muscle Weakness
- Trial name
- NCT06143475
- Testing
- FPS group, Conventional therapy group
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Arteriopathy
Effect of a Neuromuscular Electrical Stimulation Program on Walking Capacity in Peripheral Artery Disease Patients
Lower extremity peripheral arterial disease (LEPAD) is a highly prevalent chronic disease. Cardiovascular mortality of LEPAD patients at five years ranges between 18 to 30%.
- Trial name
- ELECTROPAD (NCT03795103)
- Testing
- neuromuscular electrical stimulator, Walking sessions, Advices
- Where
- 5 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Hemiplegia
The Relationship Of Ultrasonographic Measurements With Sarcopenia in Stroke
introduction:The aim of this study was to show the relationship of distal femoral cartilage and quadriceps thicknesses with functional status and presence of sarcopenia in ambulatory stroke patients with voluntary movement.
- Trial name
- NCT06254573
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kayseri City Hospital
Sporadic Inclusion Body Myositis
Blood-flow Restricted Exercise in Inclusion Body Myositis
This study evaluates the effects of a low-intensity blood-flow restricted exerciser protocol on patient reported physical function, in patients with sporadic inclusion body myositis.
- Trial name
- NCT02317094
- Testing
- Blood-flow restricted training, Care as usual
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Southern Denmark
Sarcopenia, Liver Cirrhosis
Microbiome and Sarcopenia in Patients With Liver Cirrhosis
Protein-energy malnutrition (PEM) occurs in 65-90% of patients with liver cirrhosis. Severity of malnutrition correlates with progression of liver disease and leads to sarcopenia in 30-70% of cirrhotic patients.
- Trial name
- NCT03080129
- Testing
- Fresubin energy
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Fibromyalgia
Effects of Connective Tissue Massage in Patients With Fibromyalgia
Connective tissue massage (CTM), one of the various manual therapy techniques for FMS, produces local mechanical effects on mast cells in the connective tissue with short and long tractions, thereby reducing sympathetic activity…
- Trial name
- NCT06469996
- Testing
- Connective tissue massage, Self myofascial relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Piriformis Syndrome
Effects of Reciprocal Inhibition Versus Post Facilitation Muscle Energy Technique Along With Conventional Physical Therapy in Patients With Piriformis Syndrome: a Randomized Controlled Trial
This study is a randomized controlled trial and the purpose of this study is to compare the effects of reciprocal inhibition versus post facilitation muscle energy technique along with conventional physical therapy in patients…
- Trial name
- NCT06534788
- Testing
- Reciprocal Inhibition MET, Post-facilitation MET, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Sarcopenia
Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients
This study aims to investigate the potential improvement in muscle function, compared to the placebo group, through the concurrent administration of denosumab and alfacalcidol over a one-year period in postmenopausal women with…
- Trial name
- NCT06272227
- Testing
- alfacalcidol, Denosumab
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Yonsei University
Osteoarthritis
STOP OA: A PILOT STUDY (GLA:D Canada) - Education and Targeted, Personalized Exercise for Hip and Knee Osteoarthritis
Osteoarthritis (OA) most often affects the hip and knee joints. The first signs and symptoms of pain, stiffness or swelling are not uncommon in those in their thirties and forties and 10 per cent report symptomatic knee OA by age…
- Trial name
- NCT02693873
- Testing
- GLA:D Canada (education and neuromuscular exercise program)
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Aileen Davis
Amyloid Cardiomyopathy
Unmasking the Prevalence of AC in an Unselected Echocardiographic Population
This study will investigate the prevalence of echocardiographic red-flags of amyloid cardiomyopathy (AC) in patients undergoing clinically-indicated echocardiography (observational phase) and the prevalence of AC among…
- Trial name
- AC-TIVE (NCT04738266)
- Testing
- Amyloid Cardiomyopathy
- Where
- 16 sites in Italy
- Volunteers
- 381 people
- Sponsor
- University of Trieste
Fibromyalgia
A Study to Evaluate the Effects of Milnacipran on Pain Processing and Functional MRI in Patients With Fibromyalgia
Fibromyalgia is a condition that includes pain, tenderness, stiff muscle, and fatigue. Researchers want to find out if "a drug" called milnacipran can help people with fibromyalgia.
- Trial name
- NCT01173055
- Testing
- milnacipran
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Cardiomyopathy, Dilated, 3B
CRT-P or CRT-D in Dilated Cardiomyopathy
The ICD-Reality study is a non-commercial, investigator-led, multicenter, prospective, randomized, controlled trial. We aim to determine the effect of CRT-D or CRT-P implantation in non-ischemic cardiomyopathy and heart failure…
- Trial name
- CRT-REALITY (NCT04139460)
- Testing
- CRT-D, CRT-P
- Where
- Czechia
- Volunteers
- 924 people
- Sponsor
- University Hospital Olomouc
Stroke
Cervical Proprioceptive Neuromuscular Facilitation and Stabilization Exercises in Stroke Patients
Randomization order tracking will be done with sequentially numbered containers. Patients participating in the study will be blinded as to which treatment group they will be included in.
- Trial name
- NCT06237140
- Testing
- PNF+ biofeedback exercise group
- Where
- Turkey (Türkiye)
- Sponsor
- Suleyman Demirel University
HEART DISEASE, Liver Failure
Somatic Disease Among Alcohol Abusers in an Out-day Patients' Clinic
Alcohol abuse is associated with a variety of clinical diseases, but studies on prevalence of different somatic diseases among alcohol abusers are lacking. Studies on populations in an out-day patients' clinic are also lacking.
- Conditions
- HEART DISEASE, Liver Failure, DEPRESSIVE DISORDER, Alcoholic Neuropathy
- Trial name
- NCT01081197
- Testing
- Psychiatric and somatic examinations and ,if clinical indicated, treatment
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Helse Nord-Trøndelag HF
Pneumothorax
Chronic Pain After Video-assisted Thoracoscopic Surgery (VATS) Surgery for Pneumothorax
The study will investigate characteristics of chronic pain after VATS surgery with two different sizes of videoscopic equipment.
- Trial name
- NCT00969423
- Testing
- 5mm videoscope, 10mm videoscope
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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