Clinical trials: Neuromuscular Fatigue
Fibromyalgia (FM)
Consuming of Opuntia Among Women With Fibromyalgia
To examine whether the addition of tzabar fruit twice a day to a routine daily nutrition regime will: A- Reduce symptoms of fatigue, pain and depression in FM patients B. Have positive influence on quality of life
- Trial name
- NCT05230602
- Testing
- opuntia (tzabar fruit)
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Soroka University Medical Center
Multiple Sclerosis, Diet Therapy
Investigation of the Effect of the MIND Diet on Disease Symptoms in Patients With MS
The planned parallel group, randomized controlled study design will be used to determine the effects of the MIND diet applied to MS patients on fatigue, quality of life, technological function and brain fog and to contribute to…
- Conditions
- Multiple Sclerosis, Diet Therapy, Body Composition, Randomised Controlled Trial
- Trial name
- MS (NCT07057999)
- Testing
- MIND Diet (Mediterranean-DASH Intervention for Neurodegenerative Delay), Traditional healthy nutrition program specific to Turkey
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Betul Uner
Chronic Fatigue Syndrome
Compound Ciwujia Granules Treat Chronic Fatigue Syndrome
To observe the improvement of Chalder scale score in patients with chronic fatigue syndrome treated by Compound Ciwujia Granules. Improvement =[(baseline score - post-treatment score)/baseline score]*100%
- Trial name
- NCT06245642
- Testing
- Compound Ciwujia Granules, Guipi Granules
- Where
- China
- Volunteers
- 235 people
- Sponsor
- Heilongjiang Quanle Pharmaceutical Co., Ltd.
Chronic Fatigue Syndrome
Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The purpose of this study is to determine whether therapy that has been shown to be beneficial for mitochondrial diseases is also beneficial for Chronic Fatigue Syndrome (CFS) patients.
- Trial name
- NCT01872351
- Testing
- Nutraceuticals
- Where
- United States
- Sponsor
- Columbia University
Protein Deficiency, Training Group, Sensitivity
Effects of a Multi-Ingredient Pre-Workout Supplement on Body Composition, Performance, Muscular Properties, and Wellbeing in Adults.
The investigation will be conducted as a double blinded, randomized, parallel between treatment conditions comparison design with two different groups ingesting a different supplement each one.
- Conditions
- Protein Deficiency, Training Group, Sensitivity, Fatigue, Muscular Atrophy
- Trial name
- NCT05769088
- Testing
- Ingestion of a Pre-Workout Supplement, Ingestion of a Maltodextrin Supplement
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Joel Puente
Fibromyalgia
Cannabidiol for Fibromyalgia (The CANNFIB Trial)
Fibromyalgia is serious chronic pain condition which is often accompanied by sleep disturbances, fatigue and disability and reduced quality of life.
- Trial name
- CANNFIB (NCT04729179)
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Marius Henriksen
Amyotrophic Lateral Sclerosis
Study of the Effects Strengthening Exercises in Individuals With ALS
Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease MND) among adults. Motor neurons in the spinal cord, brain stem, and cerebral motor cortex degenerate and create a variety of upper (UMN) and lower motor…
- Trial name
- NCT00204464
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Fibromyalgia, Neurocognition
Milnacipran and Neurocognition, Pain and Fatigue in Fibromyalgia : A 13-week Randomized, Placebo Controlled Cross Over Trial
This study was designed to investigate whether milnacipran is safe and effective in improving cognitive function in fibromyalgia.
- Trial name
- NCT01829243
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Sclerosis, Fatigue
Effects of Individualized Training to Reduce Fatigue in Patients With Newly and Advanced Diagnosed Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system. It is characterized by complex and heterogeneous symptoms. Chronic fatigue is the most reported symptom in MS patients (80%).
- Trial name
- MovelySEP (NCT06201026)
- Testing
- Traditional exercise, Individualized exercise
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neuralgia, Myalgia
Safety and Efficacy of Cunermuspir on Energy, Strength, and Fatigue in Patients With Nerve or Muscle Pain
Male and female participants were selected based on chronic neuromuscular pain. Patients were instructed to take two doses of the placebo or cuprous nicotinic acid chelate Cunermusmir twice a day for 28 days.
- Trial name
- NCT04737278
- Testing
- Cunermuspir
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Mitosynergy LLC
Fibromyalgia
Effects of Mobilization and Perceptive Rehabilitation on Patients With Fibromyalgia Syndrome
The aim of our study is to determine and compare the effects of perceptive rehabilitation against other mobilization techniques on the treatment of fibromyalgia symptoms and disability.
- Trial name
- NCT03705910
- Testing
- Perceptive Rehabilitation, Mobilisation Techniques
- Where
- Cyprus
- Volunteers
- 90 people
- Sponsor
- European University of Lefke
Stroke, Spasticity, Muscle
Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
- Conditions
- Stroke, Spasticity, Muscle, Muscle Fatigue, Gait, Hemiplegic
- Trial name
- COCON (NCT03342820)
- Testing
- Muscle fatigue
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Chronic Fatigue Syndrome
Based on pilot patient observations, and experience from the prior study KTS-1-2008, the investigators anticipate that chronic fatigue syndrome patients may benefit from B-cell depletion therapy using Rituximab induction with…
- Trial name
- NCT01156909
- Testing
- Rituximab
- Where
- Norway
- Volunteers
- 29 people
- Sponsor
- Haukeland University Hospital
Cancer Survivors
Effectiveness of NESA in the Treatment of Cancer Survivors
Cancer is a disease, or a set of diseases, that increased in our society. However, improvements in their detection and treatment increase the number of patients who survive.
- Trial name
- NCT06230679
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Aníbal Báez Suárez
Myalgic Encephalomyelitis, Post-acute COVID-19 Syndrome
Inspiratory Muscle Training in ME/CFS and COVID-19 Survivors
Coronavirus-2019 (COVID-19) is a viral disease leading to respiratory dysfunction, but it may also affect the brain and result in the development of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- Inspire ME (NCT05196529)
- Testing
- Inspiratory muscle training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- York University
Fatigue Syndrome, Chronic
Double Blind Trial of Duloxetine in Chronic Fatigue Syndrome
The purpose of this study is to determine the safety and efficacy of duloxetine compared with placebo for reducing fatigue in patients diagnosed with Chronic Fatigue Syndrome (CFS).
- Trial name
- CFS (NCT00375973)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Chronic Fatigue Syndrome (CFS)
MicroRNAs as Biomarkers of Pain Intensity in Patients With Chronic Fatigue Syndrome (CFS)
MicroRNAs were shown to play an important role in regulating pain-processing in a wide range of experimental models and clinical pain disorders.
- Trial name
- CFs (NCT03892954)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- King Saud University
Spinal Muscular Atrophy
Equine-Assisted Physiotherapy for Spinal Muscular Atrophy
This prospective interventional study evaluates the immediate and sustained effects of intensive equine-assisted physiotherapy in children with spinal muscular atrophy (SMA).
- Trial name
- HIPOSMA (NCT05341453)
- Testing
- Individual physiotherapy (SMA-SOC-N), Equine-Assisted Physiotherapy Based on Neuroproprioceptive Facilitation and Inhibition, Therapeutic grooming
- Where
- Czechia
- Volunteers
- 21 people
- Sponsor
- Charles University, Czech Republic
Long Covid19, Fatigue Syndrome, Chronic
Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC)
The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo to evaluate the effect of daily consumption of a cacao supplement on inflammation, endothelial damage, handgrip strength…
- Trial name
- FLALOC (NCT06064838)
- Testing
- Flavonoids
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Guillermo Ceballos Reyes
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London