Clinical trials: Neuropathic, open to volunteers
Neuropathic Pain, Spinal Cord Injury
Reliability and Validity of the Turkish Version of the SCIPI
Pain after spinal cord injury (SCI) is common, with the majority of individuals experiencing chronic pain and a significant portion reporting severe pain that interferes with their daily lives.
- Trial name
- NCT06990243
- Testing
- Evaluation Group
- Volunteers
- 40 people
- Sponsor
- Istinye University
Spinal Cord Injury, Neuropathic Pain
Effect of TMS on Neuropathic Pain for Patients With Spinal Cord Injury
Patients will be randomly assigned to three groups using a randomization scheme: active primary motor cortex (M1) rTMS, active anterior cingulate cortex (ACC) rTMS, or sham M1 rTMS.
- Trial name
- NCT07293780
- Testing
- active rTMS of M1, active rTMS of anterior cingulate cortex
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Post-thoracotomy Pain, Neuropathic Pain
SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery
This study aims to evaluate the efficacy of ultrasound-guided Serratus Posterior Superior (SPS) block compared to surgeon-administered intercostal blockade in preventing chronic pain at 3, 6, and 12 months following…
- Conditions
- Chronic Post-thoracotomy Pain, Neuropathic Pain, Postoperative Pain, Acute
- Trial name
- NCT07436806
- Testing
- SPS block, Surgical Intercostal Blockade.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Diabetic Peripheral Neuropathy (DPN)
Far-Infrared Socks for Neuropathic Pain and Nerve Function in Diabetic Patients
This study aims to evaluate the effectiveness of far-infrared radiation (FIR) emitting socks in improving neuropathic pain, nerve conduction, and quality of life in patients with diabetic peripheral neuropathy (DPN).
- Trial name
- FIR-DPN (NCT06880484)
- Testing
- Far-Infrared Radiation (FIR) Socks
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Neuropathic Chronic Pain
Assessing the Efficacy of a High-Dose Lidocaine-Tetracaine Cream for the Treatment of Peripheral Neuropathic Pain
The goal of this clinical trial is to learn if the topical anesthetic cream works to treat neuropathic chronic pain in older adults who have not found sufficient relief undergoing other pain treatments and/or medications.
- Trial name
- NCT07396129
- Testing
- Lidocaine (23%) + Tetracaine (7%)
- Volunteers
- 30 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Herpes Zoster (HZ), Traditional Chinese Medicine (TCM)
Neuropathic Pain and Traditional Medicine Syndromes in Herpes Zoster: a Cross-Sectional Study
This study investigates the relationship between neuropathic pain characteristics and Traditional Chinese Medicine (TCM) syndromes in patients with Herpes Zoster (HZ).
- Trial name
- NCT06870877
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Do Thanh Sang
Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Neuropathies
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
The "Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot study (CBD-DPN1)" is a double-blinded, placebo-controlled, crossover pilot study evaluating the efficacy of Cannabidiol (CBD) and full-spectrum CBD…
- Trial name
- CBD-DPN1 (NCT07298408)
- Testing
- Cannabidiol (CBD) oral solution, Full-Spectrum CBD hemp extract oral solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida A&M University
Neuropathic Pain, Multidisciplinary Approach
An Integrated Intervention of Spinal Cord Stimulation and Multidisciplinary Rehabilitation for Chronic Neuropathic Leg Pain: A Single-case Experimental Design Protocol
People with nerve damage can develop nerve pain. The pain can sometimes be severe and unpredictable, causing odd or alarming sensations - for example, lightning-like or electric shock feelings in the area served by the damaged…
- Conditions
- Neuropathic Pain, Multidisciplinary Approach, Rehabilitation Exercise, Acceptance & Commitment Therapy
- Trial name
- SCS-R (NCT07403331)
- Testing
- Treatment bundle
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Neuroma, Neuropathic Pain
Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap
In 2016, one in five individuals in the United States (US) experienced chronic pain, and approximately 40% of them suffered from neuropathic pain.
- Trial name
- NCT06915662
- Testing
- Tulavi allay Nerve Cap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Neuropathic Corneal Pain
Phase 3, Multi-Center, Randomized, Double-Masked, Placebo-Controlled Study Assessing the Safety and Efficacy of Urcosimod Ophthalmic Solution in Participants With Neuropathic Corneal Pain (NCP).
This study is testing a new investigational study drug called Urcosimod Ophthalmic Solution for the treatment of Neuropathic Corneal Pain (NCP).
- Trial name
- NEPTUNE (NCT07838506)
- Testing
- Urcosimod ophthalmic solution is a preservative-free topical ophthalmic product; supplied in unit dose ampoules; administered QID for 12-weeks., Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Okyo Pharma Ltd
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Diabetic Peripheral Neuropathic Pain
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
The purpose of this study is to test the safety and efficacy of study drug LY4065967 for the treatment of diabetic peripheral neuropathic pain (DPNP).
- Trial name
- NP07 (NCT07285018)
- Testing
- LY4065967
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Neuropathic Pain, Fibromyalgia
Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months.
- Trial name
- H-FINEP (NCT06250491)
- Testing
- Deep active rTMS with Hesed coil
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Nadine ATTAL
Pediatric, Neuropathic Pain
Amputations in Childhood and Neuropathic Pain
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood.
- Conditions
- Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NAPE (NCT07401966)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopitaux de Saint-Maurice
Pain
A Multi-center Clinical Longitudinal Study of Neuropathic Pain by Collecting Data
A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function
- Trial name
- NCT06290024
- Testing
- A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Type 2 Diabetes Mellitus, Painful Diabetic Peripheral Neuropathy (PDPN)
The Therapeutic Effects of Ceylon Cinnamon Supplementation and a Self-Efficacy Educational Program on Glycemic Control, Lipid Profiles, and Pain in Type 2 Diabetes Mellitus With Painful Diabetic Peripheral Neuropathy
This randomized controlled trial aims to evaluate the therapeutic effects of pure Ceylon cinnamon (Cinnamomum verum) supplementation combined with a structured self-efficacy-based educational program on glycemic control, lipid…
- Trial name
- Ceylon-EDU-RCT (NCT07757399)
- Testing
- Ceylon Cinnamon (Cinnamomum verum) Supplement, Self-Efficacy-Based Educational Program
- Volunteers
- 900 people
- Sponsor
- Jerash Private University
Diabetus Mellitus, Diabetic Foot Ulcer
The Instant Effect of Whole Body Vibration in Diabetics
Overview of Diabetes and Its Complications: Diabetes is a chronic health issue that can lead to various complications, affecting human health negatively.
- Conditions
- Diabetus Mellitus, Diabetic Foot Ulcer, Diabetic Neuropathic Ulcer
- Trial name
- NCT06878651
- Testing
- The Whole Body Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Neuropathic Pain, Chronic Postsurgical Pain
Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation
The prevalence of post-surgical lumbar neuropathic radiculopathy is approximately 30%. Poor response to the treatments recommended for neuropathic pain, namely antidepressants and/or gabapentinoids, requires the development of…
- Trial name
- NeuroPRF (NCT05196503)
- Testing
- Treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Neuropathic Pain, Radiculopathy
Hypersound Treatment for Chronic Neuropathic and Radicular Pain
This study will evaluate whether the investigational Hypersound system reduces pain in adults with chronic neuropathic or radicular pain.
- Conditions
- Chronic Neuropathic Pain, Radiculopathy, Sciatica, Peripheral Neuropathic Pain
- Trial name
- NCT07831447
- Testing
- Hypersound RF-PNS system
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Hypersound Medical Inc
Coccyx Disorder
Analgesic Efficacy of Capsaicin 8% Patch (QUTENZA®) in Coccygodygnia
A retrospective study over a period of 6 years to explore analgesic efficacy of 8% Capsaicin patch (QUTENZA®) in coccygodynic patients, as well as neuropathic predictive factors of therapeutic response.
- Trial name
- CAPSACOXp (NCT05983263)
- Testing
- Capsaicin
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Nantes University Hospital