Clinical trials: Neuropathic Pain, open to volunteers
Neuropathic Pain, Chronic Pain
Ultrasound for Peripheral Nerve Modulation
This study evaluates an ultrasound device designed to reduce pain by targeting peripheral nerves without surgery or medication. The device is placed on the skin over the area of pain and delivers controlled ultrasound…
- Trial name
- NCT07572591
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Central Post-stroke Pain, Neuropathic Pain
Thalamic-Burst-DBS for Neuropathic Pain
Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke.
- Trial name
- NCT05204472
- Testing
- Burst DBS, Tonic DBS
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain Measurement, Chronic Pain
Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing CIED Implantation Using an AID Support System
Chronic postsurgical pain (CPSP) remains a significant clinical and public health challenge despite major advances in surgical and anesthetic techniques.
- Conditions
- Pain Measurement, Chronic Pain, Cardiac Implantable Electrical Devices, Neuropathic Pain
- Trial name
- PAIN-AID (NCT07322900)
- Volunteers
- 180 people
- Sponsor
- Istanbul University - Cerrahpasa
Neuropathic Pain, Corneal Disease
Evaluation of the Clinical Efficacy and Mechanisms of Cord Plasma Eye Drops in the Treatment of Neuropathic Corneal Pain
The goal of this clinical trial is to investigate the efficacy and work of action of cord plasma eye drops in the treatment of neuropathic corneal pain (NCP).
- Trial name
- NCT07566806
- Testing
- Cord plasma eye drops
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore Eye Research Institute
Diabetic Peripheral Neuropathic Pain (DPN), Diabetic Neuropathies
Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot Study
The "Cannabidiol for the Treatment of Diabetic Peripheral Neuropathy: Pilot study (CBD-DPN1)" is a double-blinded, placebo-controlled, crossover pilot study evaluating the efficacy of Cannabidiol (CBD) and full-spectrum CBD…
- Trial name
- CBD-DPN1 (NCT07298408)
- Testing
- Cannabidiol (CBD) oral solution, Full-Spectrum CBD hemp extract oral solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida A&M University
FBSS, PSPSII
MSCS in BURSTDR Patients
The patients included in this study have already undergone the process of probe implantation and adjustment to their individually suitable stimulation pattern. Patients will be selected if the probe was implanted 0 - 5 years ago.
- Conditions
- FBSS, PSPSII, Neuropathic Pain
- Trial name
- MUSCLESCS (NCT07540663)
- Testing
- muscle simulation
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Jessa Hospital
Neuroma, Neuropathic Pain
Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap
In 2016, one in five individuals in the United States (US) experienced chronic pain, and approximately 40% of them suffered from neuropathic pain.
- Trial name
- NCT06915662
- Testing
- Tulavi allay Nerve Cap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Diabetic Peripheral Neuropathic Pain
A Study of HRS-2129 in Patients With Diabetic Peripheral Neuropathic Pain
This study aims to investigate the efficacy and safety of HRS-2129 in Chinese diabetic peripheral neuropathic pain (DPNP) in comparison to placebo.
- Trial name
- NCT07377721
- Testing
- HRS-2129 Tablets, Pregabalin Capsules
- Where
- 2 sites in China
- Volunteers
- 168 people
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Neuropathic Pain, Central Sensitization
Neuropathic Characteristics of Subacromial Pain Syndrome
This single-center observational study aims to investigate neuropathic pain descriptors and their relationship with central sensitization in patients diagnosed with subacromial pain syndrome (SAPS) who have had shoulder pain for…
- Conditions
- Neuropathic Pain, Central Sensitization, Subacromial Pain Syndrome
- Trial name
- NCT07057128
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Izmir City Hospital
Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic
Prospective Exploratory Study of a Multiomic Blood Biomarker Panel to Predict Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The goal of this prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months is to identify biomarkers to predict the overall occurrence of chronic…
- Conditions
- Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic, Taxane-induced Peripheral Neuropathy, Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Trial name
- PRECISE1 (NCT07511569)
- Testing
- longitudinal blood sampling and standardized neurological evaluation over 6 months
- Volunteers
- 192 people
- Sponsor
- Centre Hospitalier de Bligny
Human Immunodeficiency Virus, Chronic Neuropathic Pain
Low Dose Naltrexone for Pain in Patients With HIV
The increased life expectancy of Patients Living With HIV/AIDS (PLWHA) has increased the need for therapies for chronic conditions, such as chronic pain.
- Trial name
- NCT05537935
- Testing
- Low Dose Naltrexone
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement
Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS > 3) persisting beyond the expected healing period.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Hip Arthroplasty Replacement, Knee Arthroplasty, Total, Survey and Questionnaire
- Trial name
- PAIN-COMPO (NCT07110324)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Neuropathic Pain, Fibromyalgia
Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia
This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months.
- Trial name
- H-FINEP (NCT06250491)
- Testing
- Deep active rTMS with Hesed coil
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Nadine ATTAL
Chronic Post-thoracotomy Pain, Neuropathic Pain
SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery
This study aims to evaluate the efficacy of ultrasound-guided Serratus Posterior Superior (SPS) block compared to surgeon-administered intercostal blockade in preventing chronic pain at 3, 6, and 12 months following…
- Conditions
- Chronic Post-thoracotomy Pain, Neuropathic Pain, Postoperative Pain, Acute
- Trial name
- NCT07436806
- Testing
- SPS block, Surgical Intercostal Blockade.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Spinal Cord Injuries, Neuropathic Pain
Transcranial Magnetic Stimulation Therapy in Neuropathic Painful Spinal Cord Injury Patients
The aim of our study is to investigate the effect of high-frequency Repetitive Transcranial Magnetic Stimulation(rTMS) therapy applied to the dorsolateral PFC (DLPFC) area on neuropathic pain in patients with spinal cord injury.
- Conditions
- Spinal Cord Injuries, Neuropathic Pain, Neurological Diseases or Conditions
- Trial name
- NCT05645003
- Testing
- High-frequency real-time rTMS protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetic Peripheral Neuropathic Pain (DPNP)
Efficacy and Safety of Mirogabalin in Diabetic Peripheral Neuropathic Pain
The goal of this clinical trial is to learn if drug Mirogabalin works to treat diabetic peripheral neuropathic pain in adults. It will also learn about the safety of the drug Mirogabalin.
- Trial name
- NCT07451431
- Testing
- Mirogabalin, Pregabalin
- Where
- Bangladesh
- Volunteers
- 78 people
- Sponsor
- Bangladesh Medical University
Neuropathic Pain, Peripheral Neuropathic Pain
Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain
Chronic neuropathic pain (CNP) is disabling. Research on frontline treatments for CNP, shows inconsistent outcomes and dissatisfaction among Veterans.
- Trial name
- CAN (NCT05351801)
- Testing
- THC (Syndros), CBD (Epidolex), THC + CBD (Nabiximols)
- Where
- 6 sites in United States
- Volunteers
- 320 people
- Sponsor
- VA Office of Research and Development
Burn Scar Pain, Neuropathic Pain
Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study
Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue.
- Conditions
- Burn Scar Pain, Neuropathic Pain, Combat-Related Burn Injury, Scar-Related Pain
- Trial name
- US-SCAR-PAIN (NCT07438769)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Postherpetic Neuralgia, Neuropathic Pain
Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic Neuralgia
This observational study aims to compare the effectiveness of ultrasound-guided erector spinae plane (ESP) block and transcutaneous radiofrequency (RF) treatment in patients with postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Neuropathic Pain, Herpes Zoster
- Trial name
- NCT07400640
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital