Clinical trials: Neuropathic Pain, open to volunteers
Spinal Cord Injury, Neuropathic Pain
Effect of TMS on Neuropathic Pain for Patients With Sci
The aim of this study is to evaluate the efficacy of rTMS targeting the anterior cingulate cortex, another stimulation site that may be effective in the treatment of neuropathic pain, and to compare it with motor cortex…
- Trial name
- NCT07293780
- Testing
- active TMS
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Knee Pain, Chronic Knee Osteoarthritis
Treating Chronic Pain of Peripheral Nerve Origin With the Novel Noninvasive Hypersound Neuromodulation System
First, the subject will undergo screening and provide informed consent. Baseline measurements are then taken. The subject remains seated with back support throughout the session.
- Conditions
- Chronic Knee Pain, Chronic Knee Osteoarthritis, Post Surgical Neuropathic Pain
- Trial name
- NCT06626854
- Testing
- RF-PNS
- Volunteers
- 5 people
- Sponsor
- Hypersound Medical Inc
Musculoskeletal Pain, Neuropathic Pain
Association of High PainDETECT Scores With Pain Region and Diagnosis in Patients Attending a Musculoskeletal and Sports Medicine Clinic
This observational study aims to evaluate the relationship between PainDETECT questionnaire scores, pain regions, and clinical diagnoses in patients presenting to a musculoskeletal and sports medicine clinic.
- Trial name
- PD-MSK (NCT07356115)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Uskudar University
Pediatric, Neuropathic Pain
Amputations in Childhood and Neuropathic Pain
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood.
- Conditions
- Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NAPE (NCT07401966)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopitaux de Saint-Maurice
Symptomatic Neuroma, Phantom Limb Pain After Amputation
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
This prospective, observational cohort study evaluates the long-term outcomes of Regenerative Peripheral Nerve Interface (RPNI) surgery in patients with major lower extremity amputations suffering from symptomatic neuromas.
- Conditions
- Symptomatic Neuroma, Phantom Limb Pain After Amputation, Residual Limb Pain, Neuropathic Pain
- Trial name
- RPNI-AMPUTEE (NCT07420192)
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Neuropathic Pain
Evaluation of the Efficacy of STNS With FAST and MULTIWAVE in Patients With Refractory Chronic Neuropathic Pain
The goal of the study is to demonstrate Spinal Transforaminal NeuroStimulation effectiveness with FAST and other waveforms / combinations to relief neuropathic peripheral pain in chronic neuropathic pain patients, at low risk and…
- Trial name
- FORASTIM (NCT07154056)
- Testing
- Lead(s) and Implantable Pulse Generator implantation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Poitiers University Hospital
Neuropathic Pain Management, Diabetic Neuropathies, Painful
Beneficial Effects of Supplementation With CRONILIEF™ (Palmitoylethanolamide Phospholipids) in Diabetic Subjects With Neuropathic Pain.
This study aims to evaluate the potential benefit of an oral nutritional supplement based on CRONILIEF™ (Palmitoylethanolamide Phospholipids) in diabetic subjects with neuropathic pain, compared to a placebo.
- Conditions
- Neuropathic Pain Management, Diabetic Neuropathies, Painful, Palmitoylethanolamide
- Trial name
- NCT07377409
- Testing
- Cronilief™ (300 mg)
- Volunteers
- 70 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP)
Using Lymphovenous Bypass to Alleviate Diabetic Peripheral Neuropathy
Diabetes is a metabolic disease characterized by high blood sugar levels due to a lack of insulin. Long-term metabolic disorders can cause structural and functional changes in many organs, mainly affecting the vascular system…
- Conditions
- Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP), Diabetic Foot Ulcer
- Trial name
- LVB ease DPN (NCT07126197)
- Testing
- lymphovenous bypass at diseased foot dorsum
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Cancer Pain, Intractable Pain
MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain Patients
This observational study aims to evaluate changes in the spinal cord following CT-guided percutaneous cervical cordotomy performed for the treatment of intractable cancer-related pain.
- Conditions
- Cancer Pain, Intractable Pain, Spinal Cord Edema, Neuropathic Pain
- Trial name
- CORD-MRI (NCT07400055)
- Testing
- CT-guided Percutaneous Cervical Cordotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Mersin University
Diabetes Mellitus, Neuropathy
Diabetic Neuropathy in Spinal Cord Stimulator Patients
The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic…
- Conditions
- Diabetes Mellitus, Neuropathy, Neuropathic Pain, Vascular Diseases
- Trial name
- NCT04687215
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Chicago
Neuropathic Peripheral Pain
Considering Peripheral Nerve Injury, Is It Safe to Perform Transradial Angiography?
So far, apart from a limited number of case reports and small-scale studies, the frequency and severity of this complication have not been objectively evaluated using electromyography (EMG).
- Trial name
- NCT06925256
- Testing
- nerve conduction study
- Volunteers
- 100 people
- Sponsor
- Bursa City Hospital
Pain (Visceral, Somatic, or Neuropathic)
Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth
This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular…
- Trial name
- Buccal Trunk (NCT07330518)
- Testing
- Conventional Buccal Nerve Block, Buccal Nerve Trunk Block
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Watim Medical & Dental College
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Neuropathic Pain, Nociceptive Pain
Accelerated Intermittent Theta Burst Stimulation (AiTBS)on Neuropathic Pain
The present study was designed to be the first to evaluate the efficacy of the AiTBS protocol to relieve neuropathic pain in a therapeutic setting, i.e. with repeated stimulation sessions.
- Trial name
- AiTBS (NCT07148388)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injuries (SCI), Neuropathic Pain Due to Spinal Cord Injury
Virtual Walking to Reduce Chronic Neuropathic Pain in Subjects With SCI
About 70% of people with a spinal cord injury in Switzerland have chronic pain that lasts more than 3 to 6 months. This pain can be caused by muscle or joint problems, or by nerve damage (neuropathic pain).
- Trial name
- NCT07165353
- Testing
- Virtual Walking
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Neuropathic Pain
International Neuromodulation Registry
The design and execution of the International Neuromodulation Society (INS) registry has been developed with the objective of assessing the efficacy and safety of Spinal Cord Stimulation and other neuromodulation therapies using…
- Trial name
- NCT07354243
- Testing
- Neuromodulation therapies
- Volunteers
- 1,000 people
- Sponsor
- Poitiers University Hospital
Chemotherapy-induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Use of PEA and Scutellaria in Synergy With Therapeutic Exercise in Chemotherapy-induced Peripheral Neuropathy (CIPN): a Clinical Trial
This study aims to find out if taking specific dietary supplements (PEA and Scutellaria) along with therapeutic exercise can help reduce nerve pain and damage caused by chemotherapy.
- Trial name
- NCT07352514
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Neuropathic Pain, Chronic Pain
Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation
Spinal cord stimulation (SCS) relies on stimulation of pain-relieving pathways in the spinal cord to treat chronic neuropathic pain.
- Trial name
- MOPPStim (NCT03852381)
- Testing
- Spinal Cord Stimulation
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University Health Network, Toronto
Multiple Sclerosis, Chronic Pain
EXpain Trial - Exercise an a Non-pharmacological Pain-relieving Treatment in People With Multiple Sclerosis
The primary goal of this study is to test whether 12 weeks of progressive resistance exercise is an effective non-pharmacological treatment for reducing pain in people with multiple sclerosis and chronic pain.
- Conditions
- Multiple Sclerosis, Chronic Pain, Neuropathic Pain
- Trial name
- EXpain (NCT07342777)
- Testing
- Progressive resistance exercise, Usual Care followed by progressive resistance exercise
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
Corticobasal Degeneration, Corticobasal Syndrome
Scrambler Therapy for Corticobasal Syndrome-Associated Pain
The goal of this pilot trial is to test whether scrambler therapy (ST) is an effective treatment for neuropathic pain in patients with corticobasal syndrome (CBS).
- Conditions
- Corticobasal Degeneration, Corticobasal Syndrome, Pain, Neuropathic
- Trial name
- ST-CBS (NCT05653778)
- Testing
- Scrambler therapy, TENS treatment
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University