Clinical trials: Neuropathy, Diabetic
Painful Diabetic Neuropathy
Efficacy of Inhaled Cannabis in Diabetic Painful Peripheral Neuropathy
The purpose of this study is to determine if vaporized cannabis is effective as an analgesic for the treatment of painful diabetic neuropathy.
- Trial name
- NCT00781001
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Center for Medicinal Cannabis Research
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Peripheral Neuropathy
Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109)
This is an open-label, randomized, multi-center clinical trial to evaluate the safety and efficacy in peripheral neuropathies patients treated with Mecobalamin Injection
- Trial name
- NCT01192113
- Testing
- Mecobalamin IV Injection, Mecobalamin IM injection, Mecobalamin IV or IM injection
- Where
- 24 sites in China
- Volunteers
- 1,072 people
- Sponsor
- Eisai Co., Ltd.
Diabetic Foot
Multicentre Study on Diabetic Foot Treatment
With a rapidly growing incidence rate and a high disability rate,The Diabetic Foot has long been difficult to treatment, which has caused a huge burden to patients and society.
- Trial name
- MSDFT (NCT05783115)
- Testing
- Tibial Transportation Combined With Autologous mesenchymal stem cells Local Infusion, Tibial Transportation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Affiliated Hospital of Nantong University
Diabetic Peripheral Neuropathy
Effects of Virtual Reality-based Balance Training on Balance of Diabetic Peripheral Neuropathy Patients
The study aimed to clarify the effect of virtual reality-based balance training on balance in patients with diabetic peripheral neuropathy compared to conventional physical therapy.
- Trial name
- NCT05258240
- Testing
- Virtual Reality, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Autonomic Nervous System Diseases, Sweat Gland Diseases
The Effects of Liraglutide on Sudomotor Function and Inflammation in Type 2 Diabetes
The purpose of this study is to conduct an interventional, one year, randomized, double blind, placebo-controlled trial with Liraglutide in patients with type 2 diabetes (diabetes duration of >6 months and <10 years, HbA1c <10%)…
- Conditions
- Autonomic Nervous System Diseases, Sweat Gland Diseases, Diabetic Neuropathy With Neurologic Complication
- Trial name
- NCT03426085
- Testing
- Liraglutide 6 mg Solution for Injection
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Eastern Virginia Medical School
Type 2 Diabetes, Bone Disease
Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy
Objectives: The goal of this cross sectional clinical trial is to examine the phenotype of bone disease in type 2 diabetes.The main aims are to: 1.
- Conditions
- Type 2 Diabetes, Bone Disease, Osteoporosis, Diabetic Neuropathy Peripheral
- Trial name
- NCT05642143
- Testing
- Dual Energy X-ray Absorbtiometry scan, High-resolution peripheral quantitative computed tomography, Microindentation
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Aalborg University Hospital
Peripheral Diabetic Neuropathy
Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy
Type 2 DM subjects having numbness, tingling and paresthesia in hands and feet (neuropathy) will be recruited. Screening of neuropathy will be done by Michigan screening instrument.
- Trial name
- RCT (NCT06131918)
- Testing
- Resveratrol, Alpha lipoic acid, Super oxide dismutase, Resveratrol, Alpha lipoic acid
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Khyber Medical University Peshawar
Diabetic Neuropathy, Diabetes
Comparative Analysis Between Textured Insoles and Roods Technique Affecting Balance in DNP.
The purpose of this randomized controlled trial is to compare the effectiveness of textured insoles versus Rood's facilitatory technique in improving balance in patients with diabetic neuropathy.
- Trial name
- DNP (NCT07712289)
- Testing
- Roods Facilitatory Technique, Textured Insoles
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- University of Faisalabad
Diabetes Mellitus Foot Ulcer
Platelet Rich Plasma and Autologous Fat Graft for Diabetic Ulcer
Conventional management of diabetic ulcers is associated with slow healing, high costs and repeated trips to clinic. Stem cells contained in fat grafts can differentiate into pro-healing cells and release growth factors with…
- Trial name
- NCT03085550
- Testing
- Fat grafting, Fat grafting + platelet rich plasma
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Diabetic Neuropathies
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
Background: Diabetes mellitus is commonly complicated by diabetic peripheral neuropathy. Due to common side effects and poor tolerance to medication, poor adherence to medication is common in diabetic peripheral neuropathy.
- Trial name
- NCT05296759
- Testing
- botulinum toxin A, Gabapentin, Duloxetine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01154374
- Testing
- MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Skingenix, Inc.
Diabetic Peripheral Neuropathy
Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain
The purpose of this study is to determine whether low level laser therapy is effective in the reduction of foot pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT02461225
- Testing
- Erchonia® FX-635™
- Where
- 2 sites in United States, Ireland
- Volunteers
- 30 people
- Sponsor
- Erchonia Corporation
Diabetic Peripheral Neuropathy
Alter-G Training on Gait and Balance in Diabetic Neuropathy Patients
Diabetic Peripheral Neuropathy and associated complications became globally serious arousing health problems. Aim: To evaluate the effect of Antigravity treadmill training on gait performance and functional balance in patients…
- Trial name
- NCT05565924
- Testing
- Group- A (100% weight-bearing; n=14), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks., Group- B (70% weight-bearing), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks., Group- C (50% weight-bearing), (moderate-intensity (50-70% heart rate reserve) aerobic exercise training on the antigravity treadmill, 3 times/week for 12-weeks.
- Where
- Saudi Arabia
- Volunteers
- 68 people
- Sponsor
- Umm Al-Qura University
Chronic Wounds
Swab Sample Collection for the Detection of Bacterial Proteases
The objective of this study is to collect wound exudate (fluid) swab samples from Subjects who have wounds that show clinical signs of infection, as well as from Subjects who have wounds that do not show clinical signs of…
- Trial name
- NCT01881815
- Testing
- Swabs
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Systagenix Wound Management
Diabetic Foot Ulcer
Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing
This study is designed to evaluate the ability of Spatial Frequency Domain Imaging (SFDI) to measure perfusion in lower extremities for prediction of both healing and formation of diabetic foot ulcers.
- Trial name
- NCT03341559
- Testing
- Spatial Frequency Domain Imaging (SFDI)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Diabetic Foot
The Efficacy and Safety Assessment of Huafu Shengji Ointment in Patients With Diabetic Foot of Qi Deficiency and Blood Stasis Syndrome
Diabetic foot ulcers, as a complication of diabetes with high disability and mortality rates, have become a significant global healthcare burden and medical challenge worldwide.
- Trial name
- NCT06487117
- Testing
- Huafu Shengji Ointment, ethacridine lactate solution
- Volunteers
- 60 people
- Sponsor
- Beijing Daxing District Hospital of Integrated Chinese and Western Medicine
Diabetic Neuropathy
Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot
This is a study whose primary objective is to assess the effectiveness of Neuropathy/Ulcer Cream in the promotion of healing skin fissures plantar foot ulcers and as a moisturizer to prevent dry skin turning into ulcers as…
- Trial name
- NCT01951859
- Testing
- Neuropathy/Ulcer Homeopathic topical cream
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Calvary Hospital, Bronx, NY
Diabetic Foot Ulcer
RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs
To evaluate the safety and effectiveness of MIST Therapy in conjunction with Standard of Care (SOC) compared to Standard of Care alone in the treatment of diabetic foot ulcers (DFU).
- Trial name
- NCT01608776
- Testing
- MIST Therapy, SOC - Standard of Care
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Celleration, Inc.
Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP)
Using Lymphovenous Bypass to Alleviate Diabetic Peripheral Neuropathy
Diabetes is a metabolic disease characterized by high blood sugar levels due to a lack of insulin. Long-term metabolic disorders can cause structural and functional changes in many organs, mainly affecting the vascular system…
- Conditions
- Diabetic Peripheral Neuropathy (DPN), Diabetic Peripheral Neuropathic Pain (DPNP), Diabetic Foot Ulcer
- Trial name
- LVB ease DPN (NCT07126197)
- Testing
- lymphovenous bypass at diseased foot dorsum
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
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