Clinical trials: Neuropathy;Peripheral
Complex Regional Pain Syndromes, Distal Radius Fractures
Prednisone for CRPS in Distal Radius Fracture
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system.
- Trial name
- NCT06453447
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ultrasound, Education
Tele-Ultrasound: VIrtual Hands-on Education for Novice Users
This study is intended to perform a comparative analysis of novice ultrasound users when taught in person versus virtually. This study aims to show that students will not demonstrate a statistical difference in scores learning in…
- Conditions
- Ultrasound, Education, Virtual
- Trial name
- NCT05013476
- Testing
- Butterfly handheld ultrasound machine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Small Fiber Neuropathy, Diabetic Neuropathies
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study
The aim of work is to study the clinical, electrodiagnostic and neurosonographic characteristics of diabetic patients with small fiber neuropathy in the Egyptian population, and to evaluate both the diagnostic and the prognostic…
- Conditions
- Small Fiber Neuropathy, Diabetic Neuropathies, Autonomic Neuropathy, Diabetic Peripheral Neuropathy
- Trial name
- NCT05993871
- Testing
- Clinical Evaluation/Questionnaires, Nerve Conduction Study, Small fiber electrodiagnostic tests
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Charcot-Marie-Tooth Disease, Charcot-Marie-Tooth Disease Type 1A
Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A)
Charcot-Marie-Tooth neuropathy type 1A (CMT1A) is one of the most common inherited neurological disorders. The study will evaluate the efficacy and safety of an innovative rehabilitation protocol constituted by exercises at the…
- Trial name
- TreSPE (NCT01289704)
- Testing
- TreSPE, SPE
- Where
- 4 sites in Italy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Genova
Sciatica, Low Back Pain
Physiotherapy for Sciatica; Is Earlier Better?
This study aims to evaluate the whether receiving physiotherapy early after onset of the problem is better than waiting a few weeks to see if it gets better before starting physiotherapy.
- Conditions
- Sciatica, Low Back Pain, Radiculopathy
- Trial name
- POLAR (NCT02618278)
- Testing
- Physiotherapy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michael Reddington
Carpal Tunnel, Carpal Tunnel Syndrome (CTS)
Efficacy of Dorsal Kinesio Tape Application for Carpal Tunnel Syndrome in Esports Gamers: A Randomized Clinical Trial
This clinical trial investigates the effectiveness of Kinesio Tape (KT) in alleviating carpal tunnel-like symptoms and enhancing gaming performance among young adult PC gamers.
- Trial name
- NCT06993090
- Testing
- Kinesio Tape
- Where
- 3 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Diabetic Neuropathies, Diabetes Mellitus
The Effect of Sensorial Biodex Balance Balance System Exercises in Diabetic Neuropathy
This study examined the effects of balance exercises performed with the Biodex Balance System (BBS) on nerve conduction, sensory symptoms, and muscle strength in patients with diabetes-related neuropathy.
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Exercise Training
- Trial name
- NCT05255497
- Testing
- Biodex Balance Exercise System
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Duygu AKTAR REYHANIOGLU
Carpal Tunnel Syndrome
Case-control Study on Individual Risk Factors of CTS
This study is conducted to observe the characteristics of the risk factors of CTS in Chinese population.
- Trial name
- NCT03166033
- Testing
- the disease
- Where
- China
- Volunteers
- 6,048 people, healthy volunteers welcome
- Sponsor
- Fudan University
Chronic Inflammatory Demyelinating Polyneuropathy
Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating chronic progressive or relapsing neuropathy believed to be secondary to an autoimmune response against peripheral nerve antigens.5 We have…
- Trial name
- NCT01379833
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Gynecologic Cancer, Chemotherapy-induced Peripheral Neuropathy
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer
The aim of this study is to evaluate the effect of cryocompression therapy on the incidence and degree of taxane-induced peripheral neuropathy in gynecologic cancer patients receiving chemotherapy.
- Trial name
- NCT04563130
- Testing
- Cryocompression
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Duke University
Ulnar Nerve Compression, Cubital Tunnel
Sonographic Examination Cubital Tunnel Release
The investigators want to compare changes in cross-sectional area (CSA) of the ulnar nerve at the elbow after open release or endoscopic release.
- Trial name
- SPECTRE (NCT02739945)
- Testing
- Cubital tunnel release
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs), Healthy Participants
A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants
This study will evaluate bioavailability and food effect of selumetinib (AZD6244) in healthy male participants. A total of 24 healthy male participants will be included to ensure at least 20 evaluable participants.
- Trial name
- NCT03649165
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Stroke, Post-stroke Hemiparesis
Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke
The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning.
- Conditions
- Stroke, Post-stroke Hemiparesis, Foot Drop
- Trial name
- NCT05801744
- Testing
- Operant conditioning
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Sciatica
PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients
The purpose of this study is to see if the spine shows areas of inflammation using a specific type of imaging (pictures).
- Trial name
- NCT02130271
- Testing
- Radioactive dye, PET/MRI, Blood draw
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Neuropathy;Peripheral
Short Duration Electrical Stimulation to Improve Outcomes After Cubital Tunnel Release (SELECT) Trial
A novel temporary peripheral nerve stimulation system that delivers electrical stimulation therapy in a cubital tunnel release model will be evaluated for feasibility.
- Trial name
- SELECT (NCT05980767)
- Testing
- Temporary Peripheral Nerve Stimulation System
- Where
- 2 sites in Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Epineuron Technologies Inc.
Chronic Inflammatory Demyelinating Polyneuropathy, Charcot-Marie-Tooth Disease, Type IA
Quantification of Nerve Stiffness in Neuropathies
This project aims to understand how nerve mechanical properties are altered in patients with rare peripheral neuropathies . Stiffness of various peripheral nerves will be measured using ultrasound shear wave elastography.
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy, Charcot-Marie-Tooth Disease, Type IA, Anti-MAG Neuropathy
- Trial name
- Nerf_SSI (NCT03397303)
- Testing
- elastography measurements
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Charcot-Marie-Tooth Disease
A Registered Cohort Study on Charcot-Marie-Tooth Disease
The aim of the study is to analyze the natural history data data from Charcot-Marie-Tooth disease and related disorders in China, to assess the clinical, genetic, epigenetic features of patients with Charcot-Marie-Tooth disease…
- Trial name
- NCT04010188
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ning Wang, MD., PhD.
Postherpetic Neuralgia
Single-dose to Evaluate the Pharmacokinetics of GTX-101 and Subcutaneous Injectable Bupivacaine in Healthy Subjects
This is a single-center, randomized, single-dose, active-controlled study in healthy male and female subjects. The study will enroll subjects to evaluate the PK of 3 dose strengths (50 mg, 100 mg and 200 mg) of GTX-101 compared…
- Trial name
- NCT05517486
- Testing
- GTX-101, Bupivacaine HCl subcutaneous injection
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grace Therapeutics Inc.
Cervical Radiculopathy
Does the Combination of Cervical and Sacroiliac Mobilization Enhance Clinical Outcomes in Cervical Radiculopathy?
This study evaluated whether adding mobilization and myofascial techniques targeting the lumbar and sacroiliac regions to cervical-focused manual therapy provides additional clinical benefits in individuals with cervical…
- Trial name
- NCT07831070
- Testing
- Cervical manual-focused manual therapy, Extended Regional Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University