Clinical trials: Neuropathy (Disorder)
Breast Cancer, Peripheral Neuropathy, Secondary to Drugs or Chemicals
Chemotherapy Induced Peripheral Neuropathy. Could Physical Therapy Help Treat Symptoms?
The cause of Chemotherapy-Induced Peripheral Neuropathy (CIPN) is still unknown. An estimated 55-60% of patients will experience lasting symptoms affecting function for years post-treatment.
- Trial name
- NCT02239601
- Testing
- Physical Therapy
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- CancerCare Manitoba
Carpal Tunnel Syndrome (CTS)
Ultrasound-Guided Dextrose Hydrodissection of the Median Nerve
The goal of this clinical trial is to evaluate the clinical and ultrasonographic outcomes of ultrasound-guided median nerve hydrodissection with 5% dextrose in patients with mild and moderate carpal tunnel syndrome.
- Trial name
- NCT07371221
- Testing
- Ultrasound-Guided Median Nerve Hydrodissection with 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Dr. Nafiz Korez Sincan State Hospital
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female
Acupuncture Treatment of Chemotherapy-Induced Peripheral Neuropathy in Women
This pilot study aims to evaluate the feasibility to conduct a study of acupuncture treatment (AT) for Chemotherapy-Induced Peripheral Neuropathy (CIPN) at Huntsman Cancer Institute and to investigate changes in physiological…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female, Gynecologic Cancer
- Trial name
- NCT04067544
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Hereditary Spastic Paraplegia, Spastic Paraplegia Type 11
Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11)
Hereditary spastic paraparesis type 11 (SPG11) is caused by mutations in the SPG11 gene that produces spatacsin, a protein involved in lysosomal function.
- Trial name
- 3AL-SPG11 (NCT04912609)
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS Fondazione Stella Maris
Diabetic Neuropathy
The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy
In order to provide a alternative treatment for relieving the pain and numbness of Diabetes Mellitus patients,Traditional Chinese Medicine powder was tested by subjective questionnaire and objective nerve conduction velocity…
- Trial name
- NCT00886665
- Testing
- JWHGWT
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taichung Veterans General Hospital
Diabetic Neuropathy
Skin Stretch Sensory Stimuli and TENS in Diabetic Neuropathy
The aim of the research was to find and compare the effects of skin stretch sensory stimuli and transcutaneous electrical nerve stimulation (TENS) on balance in diabetic neuropathy.
- Trial name
- NCT05250999
- Testing
- Skin stretch sensory stimuli, Transcutaneous Electrical nerve stimulation, Control Group
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Diabetic Foot Ulcer
Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers
This is a phase II single-blinded study to evaluate the efficacy and safety of ALLO-ASC-DFU in patients with Diabetic Foot Ulcer, compared to standard therapy.
- Trial name
- NCT02619877
- Testing
- ALLO-ASC-DFU, Standard therapy
- Where
- 4 sites in South Korea
- Volunteers
- 59 people
- Sponsor
- Anterogen Co., Ltd.
Sciatica, Lumbosacral Radiculopathy
Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
Aim 1: The primary aim of this study is to test the feasibility of Mechanical Diagnosis and Treatment (MDT) +/- transforaminal epidural steroid injections (TESI) on pain and disability in patients awaiting physiatry consult for…
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Lumbar Disc Rupture
- Trial name
- NCT02951377
- Testing
- Exercise (MDT approach), Transforaminal epidural steroid injection (20mg dexamethasone 0.5cc lidocaine 2%)
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome, Median Neuropathy, Carpal Tunnel
Thermal and Pulsed Ultrasound for Carpal Tunnel Syndrome
This study will be a Randomized controlled trial with a sample size of at least 100 individuals with carpal tunnel syndrome. Participants will be randomized to receive either thermal ultrasound, pulsed ultrasound, a combination…
- Trial name
- NCT05838807
- Testing
- Thermal Ultrasound, Pulsed Ultrasound, Combined Ultrasound
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Ahram Canadian University
Colorectal Cancer
Peripheral Neuropathy in Colorectal Cancer Patients Under Adjuvant Chemotherapy With FOLFOX, FLOX or XELOX Regime
Oxaliplatin is a cytotoxic platinum compound and is one of the chemotherapeutic agent used in advanced colorectal cancer. It is used combined with Fluorouracil (5 FU) and Leucovorin.
- Trial name
- PENCOLA (NCT03542136)
- Testing
- VibrosSense Meter®
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University Hospital
Liver Cirrhoses, Peripheral Neuropathy
Electrophysiological Evaluation of Motor Dysfunction in Liver Cirrhotic Patients
cross sectional observational study, aimed to assess the electrophysiological function of the motor units in liver cirrhotic patients.
- Trial name
- NCT04340999
- Testing
- Nerve conduction studies and Quantitative EMG ( MUNE and IPA)
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Diabetic Foot Ulcer
The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (A6301086)
The primary objective of this 6 month open-label extension trial is to evaluate long-term safety and tolerability of dalteparin in treatment of chronic neuroischaemic foot ulcers in diabetic patients with peripheral arterial…
- Trial name
- NCT00765063
- Testing
- Fragmin
- Where
- 27 sites in Austria, Belgium and 12 more
- Volunteers
- 62 people
- Sponsor
- Pfizer
Linezolid, Tuberculosis Multi Drug Resistant Active
Linezolid Tolerance During the BPaL Regimen With Dosage Personalization Based on Therapeutic Drug Monitoring (TDM) During Multidrug-Resistant Tuberculosis Treatment
Multidrug-resistant tuberculosis (MDR-TB) poses a significant challenge to global public health. Globally, the World Health Organization (WHO) estimates the number at 400,000 patients with MDR-TB for 2023.
- Conditions
- Linezolid, Tuberculosis Multi Drug Resistant Active, Therapeutic Drug Monitoring (TDM)
- Trial name
- PLOT-TB (NCT07477119)
- Testing
- Linezolid dose personalization based on TDM
- Where
- Guinea
- Volunteers
- 150 people
- Sponsor
- Marco Schiuma
Diabetic Polyneuropathy
Pneumatic Medicine: A Transformative Treatment for Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy of the NormaTec PCD, a non-invasive pneumatic compression device with the patented peristaltic pulse pneumatic waveform, in the treatment of Diabetic Peripheral Neuropathy…
- Trial name
- NCT01175928
- Testing
- NormaTec PCD (Peristaltic Pulse PCD)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NormaTec Industries LP
Carpal Tunnel Syndrome
Acupuncture in Patients With Carpal Tunnel Syndrome ~ A Randomized Controlled Trial
To investigate the efficacy of acupuncture compared with steroid treatment in patients with mild-to-moderate carpal tunnel syndrome (CTS) as measured by objective changes in nerve conduction studies (NCS) and subjective symptoms…
- Trial name
- NCT01014221
- Testing
- Acupuncture, Prednisolone
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Kuang Tien General Hospital
Endometriosis
A Clinical Study To Investigate The Effectiveness And Safety Of Tanezumab In Treating Pain Associated With Endometriosis
The purpose of this study is to determine whether tanezumab is effective and safe in the treatment of pain associated with endometriosis.
- Trial name
- NCT00784693
- Testing
- Tanezumab
- Where
- 30 sites in United States
- Volunteers
- 48 people
- Sponsor
- Pfizer
Carpal Tunnel Syndrome
Effects of Body Structures and Function on Actıvıty and Partıcıpatıon in Patıents wıth Carpal Tunnel Syndrome
The aim of our study is to determine pain, sensation and electrodiagnostic findings in CTS; to examine its effects on activity and participation.
- Trial name
- NCT05983614
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Diabetic Foot Ulcers
Passive Training as a Treatment for Diabetic Foot Ulcers
Overall project design: This PhD project involves a randomized study on diabetic individuals with healing resistant wounds, comparing the effect of passive movement of the lower limb with standard treatment of diabetic wounds.
- Trial name
- NCT02785198
- Testing
- Passive knee extensor machine
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Leber's Hereditary Optic Neuropathy (LHON)
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection
Leber's hereditary optic neuropathy (LHON) is a rare mitochondrial genetic disorder characterized by optic nerve atrophy due to the degeneration of retinal ganglion cells, which leads to acute visual loss.
- Trial name
- NCT05555784
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Argo Sante
Diabetic Foot Ulcers
Utilization of Platelet Gel for Treatment of Diabetic Foot Ulcers
Diabetes is a multiorgan disease and considered a major health problem in different societies. One of the complications the pain particularly in the extremities resulting from a process known as diabetic foot ulcer.
- Trial name
- NCT02134132
- Testing
- Platelet Gel
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Royan Institute
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