Clinical trials: Neuropathy (Disorder)
Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
- Trial name
- NCT05783245
- Testing
- Polarcare Machine, Standard of care ice therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Chicago
Diabetes Mellitus, Type 1
Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue
Influence of diabetic neuropathy on cold induced brown adipose tissue in type 1 diabetic patients.
- Trial name
- DIA-BAT (NCT03695731)
- Testing
- cold induced activation of brown adipose tissue
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Doctor Giacomo Gastaldi
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Magnetic Resonance Diagnostics of Diabetic Peripheral Neuropathy
This project aims to develop high field MR techniques to detect nerve lesions in diabetic patients. The MRI findings will be compared to results from conventional evaluations and nerve conduction studies to determine the validity…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy, Hereditary Axonal Neuropathy
- Trial name
- NCT01847937
- Where
- 5 sites in Denmark, Germany
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Diabetic Peripheral Neuropathic Pain
A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The primary purpose of this study is to evaluate the safety and efficacy of medical cannabis aerosol containing 0.25, 0.50, 1.0 milligrams (mg) delta (Δ) 9-tetrahydrocannabinol (THC) inhaled three times a day (TID) compared to…
- Trial name
- NCT06490445
- Testing
- Medical Cannabis
- Where
- 38 sites in Australia, Czechia and 3 more
- Volunteers
- 122 people
- Sponsor
- Syqe Medical
Carpal Tunnel Syndrome
Comparison of Difference Hydrodissection for CTS
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT03031041
- Testing
- Ultrasound-guided short-axis hydrodissection with 5cc normal saline, Ultrasound-guided long-axis hydrodissection with 3cc normal saline
- Where
- Taiwan
- Volunteers
- 47 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Diabetes Mellitus, Diabetic Foot
Five-year Mortality Rate in People With Diabetic Foot Ulcer
As the global mortality rate decreases for diabetics patients, further explorations and datas are needed about the specific population of diabetics patients suffering a Diabetic Foot Ulcer (DFU).
- Conditions
- Diabetes Mellitus, Diabetic Foot, Diabetes Complications
- Trial name
- DIAFOOT (NCT03782129)
- Testing
- blood samples, Clinical exam and DFU medical cares
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Acute Pain, Breast Carcinoma
Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel
This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel.
- Conditions
- Acute Pain, Breast Carcinoma, Peripheral Neuropathy
- Trial name
- NCT02297412
- Testing
- Minocycline Hydrochloride, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 12 sites in United States
- Volunteers
- 47 people
- Sponsor
- Academic and Community Cancer Research United
Familial Dysautonomia
The Safety and Tolerability of Kinetin, in Patients With Familial Dysautonomia
This is a study of kinetin, a nutritional supplement that corrects the mRNA splicing defect in patients with familial dysautonomia (FD, also known as Riley Day syndrome or hereditary sensory and autonomic neuropathy type III).
- Trial name
- NCT02274051
- Testing
- Kinetin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Amyloid Cardiomyopathy, Transthyretin Cardiac Amyloidosis
Exercise Training in Transthyretin Cardiac Amyloidosis
Transthyretin cardiac amyloidosis causes debilitating heart failure in older adults. The proposed research will develop a personalized exercise training program to improve functional capacity in patients on optimal treatment for…
- Trial name
- NCT05797857
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer
The aim of this study is to assess the effects of n-3 fatty acids on taxane-induced neuropathy and neurotoxic inflammatory agents in patients suffering from invasive breast cancer.
- Trial name
- NCT01049295
- Testing
- oil fish, corn oil pearls
- Where
- Iran
- Volunteers
- 52 people
- Sponsor
- Tehran University of Medical Sciences
Diabetic Neuropathy With Neurologic Complication
Balance Training in Diabetic Neuropathy
This study evaluates the efficacy of balance training in Diabetic Neuropathy. Control group will receive general exercises while Eperimental/ Interventional group will receive Balance exercises along with general exercises.
- Trial name
- NCT04232995
- Testing
- Balance Training, General Exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Diabetic Neuropathy
The Evaluation of Safety and Efficacy of JWHGWT on Diabetic Neuropathy
In order to provide a alternative treatment for relieving the pain and numbness of Diabetes Mellitus patients,Traditional Chinese Medicine powder was tested by subjective questionnaire and objective nerve conduction velocity…
- Trial name
- NCT00886665
- Testing
- JWHGWT
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taichung Veterans General Hospital
Carpal Tunnel, Dexmedetomidine
Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief
The aim of the present study is to compare the analgesic efficacy of Dexmedetomidine, Ozone and Dexamethasone regional injection in carpal tunnel syndrome.
- Conditions
- Carpal Tunnel, Dexmedetomidine, Ozone, Dexamethasone
- Trial name
- NCT06133712
- Testing
- Dexmedetomidine, Ozone, Dexamethasone
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Chronic Pain, Carpal Tunnel Syndrome
Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modaleties are available for treatment of mild to moderate CTS.
- Trial name
- NCT04961281
- Testing
- Dexmedetomidine, Triamcinolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Peripheral Neuropathies
Synergic Control of Posture in Peripheral Neuropathies' Patients
This is a multicenter observational study aimed to characterize multi-muscle synergy organization in relation to postural stability in individuals with Peripheral Neuropathies (PN) compared to healthy age-matched subjects and to…
- Trial name
- NEUPER (NCT05088681)
- Testing
- Rehabilitation program
- Where
- 2 sites in Italy
- Volunteers
- 26 people
- Sponsor
- University of Milano Bicocca
Diabetic Foot, Diabetic Dermopathy
The Role of Skin Microecology in Diabetic Skin Lesions
This study is an observational study. Collect cotton swabs of the surface skin are obtained from the non-diabetic and diabetic patients hospitalized in the Nanfang Hospital of Southern Medical University.
- Trial name
- NCT04916457
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Neuralgia, Neuropathic Pain
Safety and Effectiveness of Magnetic Peripheral Nerve Stimulation for the Treatment of Chemotherapy Induced Neuropathy
Assess the safety and effectiveness of Axon Therapy in the treatment of chemotherapy-induced neuropathy
- Conditions
- Neuralgia, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- mPNS-CH (NCT05935956)
- Testing
- Magnetic Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- NeuraLace Medical, Inc.
Carpal Tunnel Syndrome
Sonographic Evaluation of Patients With Carpal Tunnel Syndrome Following Steroid Injection
The objective of this study was to assess sonographic changes of the median nerve after steroid injection for carpal tunnel syndrome.
- Trial name
- NCT03132051
- Testing
- steroid injection
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Familial Amyloid Neuropathy, Transthyretin Amyloidosis
Assessment of the Prevalence of TTR Amyloid Neuropathy in a Population of Patients With Neuropathy of Unknown Aetiology
Familial amyloid neuropathy due to transthyretin gene mutations (TTR-FAP) is a rare autosomal dominant inherited disease resulting in the abnormal multi-system deposition of amyloid proteins.
- Trial name
- PRE-TRANS (NCT03190577)
- Testing
- blood sample
- Where
- 12 sites in France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Breast Cancer, Neuropathy;Peripheral
Efficacy and Safety of HILOTERM® Device for the Prevention of Peripheral Neuropathy
Taxol is a very effective drug in breast cancer, but it can cause peripheral neuropathy (PN). This toxicity is often dose-limiting.
- Trial name
- NCT06422949
- Testing
- Hilotherm® Cooling treatment
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
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