Clinical trials: Neuropathy (Disorder)
Diabetes Complications
Silicone Sock as Treatment of Deep Heel Fissures in People With Diabetes
This study evaluates the addition of using a sock of silicone to using a heel cream, in the treatment of heel fissures in people with diabetes, aiming at healing the fissures and preventing them from developing into ulcers.
- Trial name
- NCT02641548
- Testing
- Sock of silicone, Heel cream
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Region Örebro County
Sensory Neuropathy, Small Fiber Neuropathy
IVIG in Painful Sensory Neuropathy
The goal of this clinical trial is to assess effect of Intravenous immunoglobulins (antibodies) as compared to Placebo, on pain intensity in patients from 18-65 years with painful sensory neuropathy without a known cause.
- Trial name
- NCT06183008
- Testing
- Intravenous immunoglobulin
- Volunteers
- 20 people
- Sponsor
- Sorlandet Hospital HF
Diabetic Neuropathy
ACUpuncture in Diabetic Peripheral Neuropathy
Multicentric,randomized, two-armed confirmatory trial on the effectiveness of acupuncture in patients with symptomatic peripheral diabetic neuropathy compared to routine care.
- Trial name
- ACUDPN (NCT03755960)
- Testing
- acupuncture, routine care
- Where
- 2 sites in Germany
- Volunteers
- 62 people
- Sponsor
- Benno Brinkhaus
Cardiac Amyloidosis
Identification of Prognostic Parameters in Patients With " Senile " Amyloid Cardiomyopathy
The aging of the population is a reality in our society, with a strong increase in the number of elderly patients hospitalized for heart failure in our institutions.
- Trial name
- EVAMYLOSE (NCT04225754)
- Where
- France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Grenoble
Diabetes Mellitus, Peripheral Neuropathies
Effects of Pregabalin, Duloxetine & Amitriptyline on Pain & Sleep
The purpose of this study is to assess the effectiveness of pregabalin, duloxetine and amitriptyline compared with placebo in reducing pain in diabetic patients as assessed by Brief Pain Inventory (BPI).
- Trial name
- NCT00370656
- Testing
- Pregabalin, Duloxetine, Amitriptyline
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Surrey
Diabete Mellitus, Diabetic Foot
Effect of Self- and Family Management of Diabetic Foot Ulcers Programs on Health Outcomes
Brief description: Diabetic foot ulcer (DFU) is described as a full-thickness lesion appearing at the skin of the foot along with infection, destruction of tissues due to neuropathy and/or peripheral artery disease (PAD) in…
- Trial name
- NCT03909802
- Testing
- Self-and family management of diabetic foot ulcers programs, Usual care
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Dysthyroid Orbitopathy
Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy
The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.
- Trial name
- NCT00665795
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo
Carpal Tunnel Syndrome (CTS)
Efficacy And Tolerability Of Alpha Lipoic Acid And Vitamin B Preparation In Carpal Tunnel Syndrome
The goal of this clinical trial is to assess the effectiveness and safety of an oral combination of alpha lipoic acid (ALA) and vitamin B complex in treating mild to moderate carpal tunnel syndrome (CTS) in adults.
- Trial name
- NCT06940557
- Testing
- Bionerv
- Where
- Malaysia
- Volunteers
- 70 people
- Sponsor
- Universiti Putra Malaysia
Diabetic Neuropathy Peripheral
Nicotinamide Riboside for Diabetic Neuropathy
At the current time there is no effective disease modifying therapy for diabetic neuropathy (DN). The proposed study design employs a quantifiable early measure of DN, intraepidermal nerve fiber density (IENFD), allowing for…
- Trial name
- NiRiD (NCT03685253)
- Testing
- Niagen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Colon Neoplasms, Colorectal Neoplasms
Ultrasound Therapy and Therapeutic Exercise for Chemotherapy Induced Peripheral Neuropathy (CIPN)
The primary purpose of the trial is to determine the preliminary efficacy of therapeutic ultrasound in the treatment of pain and sensory disturbance related to chemotherapy induced peripheral neuropathy.
- Trial name
- ULTRA (NCT02499939)
- Testing
- Standard Care, Ultrasound Therapy
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Margie McNeely
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ischemic Stroke
Effect of EA Combined With NGF on Limb Function in Convalescent Patients With Ischemic Stroke
Most ischemic stroke patients are in recovery phase, often accompanied by motor impairment, but they lack effective treatment. The appearance of nerve growth factor (NGF) promotes the development of neuroprotective therapy, but…
- Trial name
- NCT05652751
- Testing
- nerve growth factor, physiological saline, EA
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Neuropathic Pain, Diabetic Neuropathies
rTMS for the Treatment of Neuropathic Pain in Diabetic Patients
Tis study aims to assess whether multiple sessions of sham-controlled HF-rTMS applied to the motor cortex significantly reduces treatment-resistant neuropathic pain in diabetic patients.
- Trial name
- NCT05792072
- Testing
- rTMS
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitair Ziekenhuis Brussel
Carpal Tunnel Syndrome, Carpal Tunnel Release
Carpal Tunnel Release Through Mini Transverse Approach
Carpal tunnel release through dorsal wrist crease Mini Transverse incision, about 1.5 cm length.
- Conditions
- Carpal Tunnel Syndrome, Carpal Tunnel Release, Carpal Tunnel Surgery, Carpal Tunnel Transverse Approach
- Trial name
- CTRMTA (NCT02766114)
- Testing
- Carpal tunnel release through Mini Transverse Approach
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Diabetic Foot Ulcers
Utilization of Platelet Gel for Treatment of Diabetic Foot Ulcers
Diabetes is a multiorgan disease and considered a major health problem in different societies. One of the complications the pain particularly in the extremities resulting from a process known as diabetic foot ulcer.
- Trial name
- NCT02134132
- Testing
- Platelet Gel
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Royan Institute
Carpal Tunnel Syndrome
Evaluation of Ecography as a Diagnostic Tool in the Carpal Tunnel Syndrome Compared to the Studies of Electroconduction
The main objective is to investigate the value of ultrasound in the diagnosis of Carpal Tunnel Syndrome (CTS), and among the secondary objectives, to establish the ultrasound parameters that are predictors of CTS in comparison…
- Trial name
- NCT05556278
- Testing
- Ultrasound study, Neurophysiological test
- Where
- Spain
- Volunteers
- 438 people
- Sponsor
- Hospital Universitario Virgen Macarena
Peripheral Arterial Disease
Stimulation TcPO2 Test in the PAD Diagnosis in Diabetic Foot
All diagnostic procedures of peripheral arterial disease (PAD) in the diabetic foot (DF) are limited due to diabetes mellitus and its late complications.
- Trial name
- stimTcPO2 (NCT04404699)
- Testing
- Stimulation TcPO2 test
- Where
- Czechia
- Volunteers
- 79 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Real Life Study, TLC-NOSF Dressings
Clinical Evaluation in Real Life of TLC-NOSF Dressings in the Local Treatment of Chronic Wounds (DFU and VLU)
The objective of this study is to document the performance and the safety of UrgoStart Plus® Border, UrgoStart Plus® Pad and UrgoStart Interface® in the local treatment of diabetic foot ulcers (neuropathic or neuroischemic …
- Conditions
- Real Life Study, TLC-NOSF Dressings, Venous Leg Ulcer, Diabetic Foot Ulcer
- Trial name
- STARTLIFE (NCT06135987)
- Testing
- TLC-NOSF dressings (D'URGOSTART PLUS® BORDER, URGOSTART PLUS® PAD and URGOSTART INTERFACE®)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Laboratoires URGO
Painful Diabetic Neuropathy
Feasibility of Self-treatment of Painful Diabetic Neuropathy Using Electrical Vasomotor Nerve Stimulation
Electrical stimulation with EVNS (Electrical Vasomotor Neuro Stimulation), a methodology used by a specific group of neurostimulators known under various names, has proven its benefit in Painful Diabetic Neuropathy (PDN).
- Trial name
- HOME-EVNS (NCT06524284)
- Testing
- Releaf
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Neurecon BV
Diabetic Foot Ulcer
Prognostic Determinants in Patients With Diabetic Foot Ulcer.
The worse prognosis observed in patients with Diabetic Foot Ulcer (DFU) has not been fully understood. Poor prognosis may be related to other conditions (inflammation, infectious disease, cancers) further to cardiovascular…
- Trial name
- PDF (NCT04533152)
- Where
- 26 sites in France, Martinique
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Bordeaux
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