Clinical trials: Neurophysiologic Monitoring, open to volunteers
Acute Brain Injury, Mechanical Ventilation
Brain Monitoring During PEEP-Based Respiratory Therapy in Critically Ill Patients
Mechanical ventilation is commonly used in critically ill patients with acute brain injury. Positive end-expiratory pressure (PEEP) and lung recruitment maneuvers are important ventilator strategies for improving oxygenation, but…
- Conditions
- Acute Brain Injury, Mechanical Ventilation, Neurocritical Care
- Trial name
- NCT07716787
- Testing
- Recruitment Maneuver, Positive End-Expiratory Pressure Adjustment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shengli Oilfield Hospital
Intraoperative Neurophysiological Monitoring, Magnesium Sulfate
Effect of Magnesium Sulfate Bolus on Intraoperative Neuromonitoring
Magnesium Sulfate(MgSo4) is increasingly being used as part of the multimodal pain regimen in the perioperative period. The intraoperative neurophysiological monitoring (IONM) is utilized in complex spine and cranial surgeries to…
- Trial name
- NCT04938765
- Testing
- Magnesium sulfate, Normal Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Brain Neoplasms, Eloquent Area Brain Tumors
CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial
This study is designed for patients with brain tumors located in eloquent brain areas involved in language, motor, or major functional brain networks.
- Trial name
- CONNECT Trail (NCT07657403)
- Testing
- Connectome-Guided Navigation-Assisted Microsurgical Resection, Conventional DTI Tractography-Guided Tumor Resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Spinal Disease, Anesthesia
Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds
The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.
- Conditions
- Spinal Disease, Anesthesia, Post Operative Pain
- Trial name
- NCT06792474
- Testing
- Lidocaine in Saline, Normal saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Intraoperative Neurophysiological Monitoring, Malignant Brain Tumors
Intraoperative Neurophysiological Monitoring in Brain Tumor Surgery: Prospective Cohort Studies
BACKGROUND Brain tumor surgery requires balancing two competing priorities: maximizing the extent of tumor resection to improve survival while preserving neurological function.
- Conditions
- Intraoperative Neurophysiological Monitoring, Malignant Brain Tumors, Motor Evoked Potential Monitoring, Cortico-cortical Evoked Potential Monitoring
- Trial name
- NCT07789938
- Testing
- Intraoperative neurophysiological monitoring, no Intraoperative neurophysiological monitoring
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- Odense University Hospital
Thyroid Disease, Thyroid Surgery
Continuous Lidocaine Infusion in Thyroid Surgery Using Intraoperative Neurophysiological Monitoring
Thyroid surgery is a common procedure for the treatment of thyroid tumors, nodules and other related lesions. During this procedure, intraoperative neurophysiological monitoring is used to protect the recurrent laryngeal nerves.
- Conditions
- Thyroid Disease, Thyroid Surgery, Lidocaine Infusion
- Trial name
- NCT06785987
- Testing
- Continuous Lidocaine Infusion, intermittent fentanyl infusion, Continuous remifentanil Infusion
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Spinal Cord Neoplasms, Spinal Neoplasms
Remimazolam vs Propofol for Motor and Somatosensory Evoked Potentials in Spinal Tumor Surgery
Intraoperative neurophysiological monitoring (IONM) using motor evoked potentials (MEP) and somatosensory evoked potentials (SEP) is routinely applied during spinal tumor resection to detect impending neurological injury.
- Trial name
- NCT07901504
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Vestibular Schwannoma, Facial Nerve Paralysis
Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients
The purpose of this study is to evaluate the efficacy and safety of steroids treatment compared with placebo in preserving facial nerve function after craniotomy in patients with vestibular schwannoma who have not received…
- Trial name
- SAF-NRVS (NCT07116811)
- Testing
- Steroids therapy
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Beijing Tiantan Hospital
Spine Surgery, Intraoperative Neurophysiological Monitoring
Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Neurophysiological Monitoring
This randomized controlled trial will compare two strategies for rocuronium use during general anesthesia for spine surgery with intraoperative neurophysiological monitoring.
- Conditions
- Spine Surgery, Intraoperative Neurophysiological Monitoring, Neuromuscular Blockade
- Trial name
- ROC-IONM (NCT07627750)
- Testing
- Low-Dose Rocuronium Maintenance, Rocuronium
- Where
- Vietnam
- Volunteers
- 62 people
- Sponsor
- Bach Mai Hospital
Intraoperative Neurophysiological Monitoring, Spine Surgery
Ciprofol and Remimazolam for Intraoperative Neurophysiological Monitoring During Spine Surgery
Intraoperative neurophysiological monitoring, including motor evoked potentials and somatosensory evoked potentials, is commonly used during spine surgery to help detect impending neurological injury.
- Conditions
- Intraoperative Neurophysiological Monitoring, Spine Surgery, Anesthesia
- Trial name
- CIRIONM (NCT07718152)
- Testing
- Ciprofol, Remimazolam
- Volunteers
- 60 people
- Sponsor
- Affiliated 2 Hospital of Nantong University
Intraoperative Neurophysiological Monitoring
MINDZ-- Minimally Invasive Approach Pilot Study
This clinical investigation is a pilot, first-in-human (FIH) study designed to demonstrate proof of concept, safety, and functional performance of the MINDZ subdural electrode grid when used in relevant neurosurgical settings.
- Trial name
- MINDZ-MAP (NCT07543406)
- Testing
- MINDZ Subdural Electrode Grid
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Neurosoft Bioelectronics SA